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IL-15 Products
IL-15 (Interleukin 15) is a cytokine that induces or enhances the differentiation, maintenance, or activation of multiple T cell subsets including NK, NKT, Th17, Treg, and CD8+ memory cells. It also induces dendritic cell differentiation and inflammatory activation, exhibits anti-tumor activity, and inhibits the deposition of lipid in adipocytes. Complexes of IL-15 with cell surface IL-15 R alpha interact with complexes of IL-2 R beta and the Common gamma Chain on adjacent cells. This transpresentation mechanism enables cells to respond to IL-15 even if they do not express IL-15 R alpha. Ligation of membrane-associated IL-15/IL-15 R alpha complexes also induces reverse signaling that promotes activation of the IL-15/IL-15 R alpha expressing cells. The activity of circulating IL-15 is limited by its association with soluble IL-15 R alpha.
49 results for "IL-15" in Products
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IL-15 Products
IL-15 (Interleukin 15) is a cytokine that induces or enhances the differentiation, maintenance, or activation of multiple T cell subsets including NK, NKT, Th17, Treg, and CD8+ memory cells. It also induces dendritic cell differentiation and inflammatory activation, exhibits anti-tumor activity, and inhibits the deposition of lipid in adipocytes. Complexes of IL-15 with cell surface IL-15 R alpha interact with complexes of IL-2 R beta and the Common gamma Chain on adjacent cells. This transpresentation mechanism enables cells to respond to IL-15 even if they do not express IL-15 R alpha. Ligation of membrane-associated IL-15/IL-15 R alpha complexes also induces reverse signaling that promotes activation of the IL-15/IL-15 R alpha expressing cells. The activity of circulating IL-15 is limited by its association with soluble IL-15 R alpha.
49 results for "IL-15" in Products
| Source : | E. coli |
| Accession # : | P40933.1 |
| Applications : | Bioactivity |
Intended for preclinical researchers who may transition to GMP IL-15 for their clinical work
| Source : | E. coli |
| Accession # : | P40933.1 |
| Applications : | Bioactivity |
Animal-Free
| Source : | E. coli |
| Accession # : | P40933.1 |
| Applications : | Bioactivity |
| Sensitivity : | 2 pg/mL |
| Assay Range : | 3.9 - 250 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
| Source : | E. coli |
| Accession # : | P48346 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #34593 |
| Applications : | ELISA Detection, Western Blot |
Simple Plex Human IL-15 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #34559 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #34593 |
| Applications : | Block/Neutralize, Western Blot |
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #34505 |
| Applications : | Block/Neutralize, ELISA Capture |
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #34559 |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #34559 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #34559 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #201136 |
| Applications : | ELISA Capture, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #1048222 |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #34559 |
| Applications : | Flow Cytometry |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
