What is the reason for the recommendation to use 35 µL sample volume, instead of the default 50 µL volume, for Luminex multiplex containing > 25 analytes, when assayed on Luminex MAGPIX® analyzer?

R&D Systems recommend 35 µL sample volume for > 25 analytes to control the number of beads in the sample load when using Luminex MAGPIX® analyzer. Luminex MAGPIX® analyzer is a non-flow-based reader which utilizes a magnet to hold the magnetic microparticles in a monolayer in a chamber where the beads are imaged and then processed by the software to generate data. Since MAGPIX® system pushes the entire Sample Load Volume into the chamber, multiplex assay containing > 25 analytes may overload the chamber capacity with 50 µL sample load default setting. The captured images can have too many beads in them to give accurate results, and some of the analytes/regions may present lower than desired bead counts.

Does the Luminex Human Magnetic Assay detect soluble form or membrane-bound analyte?

The sample types typically validated by R&D Systems for Luminex assays contain soluble form of proteins, and therefore it is expected that the soluble form of proteins are detected. It is possible there are assays that alo detect the membrane form of respective target proteins, however, R&D Systems does not generally evaluate our assays against samples known to contain membrane-bound proteins.

What speed do you recommend centrifuging cell culture supernates samples?

For cell culture supernates, remove particulates by centrifuging for 5 minutes at 500 x g.

Human Luminex® Discovery Assay

Name: Human Luminex® Discovery Assay
Brand: R&D Systems
SKU: LXSAHM
Rating: 5 (36 reviews)

R&D Systems, Inc. a Bio-Techne Brand

Catalog # LXSAHM

Citations (402)

(36)

Product Datasheet / COA / SDS

Luminex Discovery Assays

Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.

Build your own Luminex Assay with our Luminex Assay Customization Tool.

Build Now

Setting the standard in quality research reagents

Key Product Details

Assay Type:	Magnetic bead-based multiplex assay for the Luminex^® platform
Format:	1 x 96-well microplate and magnetic antibody-coated beads
Species:	Human
Analytes Detected:	Select from over 350 analytes to build your custom panel using our assay customization tool below.

View Full Technical Details for Human Luminex® Discovery Assay

Product Features for Human Luminex® Discovery Assay

Magnetic Luminex Assays are the most flexible bead-based multiplex assays that we offer. They allow up to 50 user-defined target analytes to be simultaneously profiled using cell culture supernates, serum, or plasma samples.

Simultaneously profile up to 50 analytes of your choice in one sample

Choose from a wide menu of analytes, including many unique analytes
Requires a small sample volume (<50 µL)
Run your assay in just 3-4 hours
Mass-calibrated standards for consistent results with every new lot of material
Enough reagents for one 96-well plate
Quick turn-around time: Kits are typically shipped within 5-10 days of ordering.*

Please allow additional time for international orders.

Performance Validation for Human Luminex® Discovery Assay

Luminex Assays are validated for use with cell culture supernatants, plasma and serum. All Luminex assays are tested for sensitivity, intra-assay precision, inter-assay precision and to ensure assay linearity for validated sample types. Antibody pairs are selected and tested to confirm the parallel detection of natural and recombinant standard protein and to ensure the accurate determination of target analytes within biological samples. Assays for each target analyte are screened against all target analytes to confirm low antibody cross-reactivity.

Kit Components for Human Luminex® Discovery Assay

Premixed cocktail of antibody-coated Magnetic beads
Premixed cocktail of biotinylated detection antibody
Standard Cocktail(s)
Bead Diluent
Biotin Antibody Diluent
Calibrator Diluent
Wash Buffer
Streptavidin-PE
One flat-bottom 96-well Microplate
Foil Plate Sealers (4)
Mixing Bottle
Standard Value Card**

**A standard curve must be generated each time an assay is run, utilizing values from the Certificate of Analysis provided with each Luminex Assay.

Build Your Assay

Make Your Selections Below to Configure Your Custom Luminex Assay

Assays

Below are kits that are available based on your selections. These selections may be further customized before adding to the cart or emailing the configuration to your purchasing department or local distributor to place your order. Selected analytes may be included in more than one High Performance Assay. All assay options are displayed.

If you run into bead region incompatibilities, send your Luminex code to our team and find out more.

How would you like these analytes mixed?

Premixed

User Mixed

Please select at least one mixing option to see the kits.

Would you like to split based on dilution?

Do not split

Split based on serum

Split based on plasma

Split based on cell culture supernates

Which Luminex Assay is Right For Me?

Assays for the Luminex platform are offered as High Performance Assays or Discovery Assays . The Luminex High Performance Assays are fully validated panels with a focused selection of analytes. They are available as Configurable User Mix and Premixed options or as Fixed Panels. The Luminex Discovery Assays allow for the maximum number of analytes in a multiplex and is supplied as a premixed kit. View a table comparing the features and benefits of these bead-based multiplex assays on rndsystems.com .

More Information About Magnetic Bead-based Multiplex Kits For The Luminex® Platform

Magnetic Luminex High Performance Assays are designed for use with the Luminex MAGPIX CCD Imager. Alternatively, kits can be used with the Luminex 200™ or FLEXMAP 3D, dual laser, flow-based sorting and detection platforms.

Analyte-specific antibodies are pre-coated onto color-coded microparticles. Microparticles, standards, and samples are pipetted into wells and the immobilized antibodies bind the analytes of interest. After washing away any unbound substances, a biotinylated antibody cocktail specific to the analytes of interest is added to each well. Following a wash to remove any unbound biotinylated antibody, Streptavidin-Phycoerythrin conjugate (Streptavidin-PE), which binds to the biotinylated detection antibodies, is added to each well. A final wash removes unbound Streptavidin-PE and the microparticles are resuspended in buffer and read using a Luminex analyzer. One laser is bead-specific and determines which analyte is being detected. A magnet in the analyzer captures and holds the superparaMagnetic microparticles in a monolayer. Two spectrally distinct Light Emitting Diodes (LEDs) illuminate the beads. One LED identifies the analyte that is being detected and the second LED determines the magnitude of the PE-derived signal, which is in direct proportion to the amount of analyte bound. Each well is imaged with a CCD camera. Kits can also be used with Luminex 100/200 or a FLEXMAP 3D dual laser, flow-based systems.

Preparation and Storage

Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Product Specific Notices for Human Luminex® Discovery Assay

Luminex® is a registered trademark of Luminex Corporation.

Citations for Human Luminex® Discovery Assay (402)

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Citations are publications that use Bio-Techne products. Selected citations for Human Luminex® Discovery Assay include:

Species: Human
Sample Types: Cell Culture Supernates

C Mondadori et al. (2023), Assessing the response of human primary macrophages to defined fibrous architectures fabricated by melt electrowriting Bioactive materials, 21(0):209-222.
PMID: 36101857
Species: Human
Sample Types: Plasma

P Sampath et al. (2023), Cytokine upsurge among drug-resistant tuberculosis endorse the signatures of hyper inflammation and disease severity Scientific Reports, 13(1):785.
PMID: 36646786
Species: Human
Sample Types: Serum

SS Wang et al. (2022), Host characteristics associated with serologic inflammatory biomarkers in women Cytokine, 149(0):155726.
PMID: 34666235
V Selvaraju et al. (2022), Multiplexed measurements of salivary fetuin-A, insulin, and adiponectin as potential non-invasive biomarkers in childhood obesity Cytokine, 153(0):155843.
PMID: 35255380
Species: Human
Sample Types: Serum

DW Han et al. (2022), Extracellular pyruvate kinase M2 promotes osteoclastogenesis and is associated with radiographic progression in early rheumatoid arthritis Scientific Reports, 12(1):4024.
PMID: 35256696
Species: Human
Sample Types: Plasma

M Weitoft et al. (2022), Plasma proteome changes linked to late phase response after inhaled allergen challenge in asthmatics Respiratory Research, 23(1):50.
PMID: 35248034
Species: Human
Sample Types: Cell Culture Supernates

K Tuerxun et al. (2022), Cytokine responses to LPS in reprogrammed monocytes are associated with the transcription factor PU.1 Journal of leukocyte biology, 0(0).
PMID: 35285058
Species: Human
Sample Types: BALF

SH Lee et al. (2022), NADPH oxidase 4 signaling in a ventilator-induced lung injury mouse model Respiratory Research, 23(1):73.
PMID: 35346198
Species: Human
Sample Types: Plasma

YJ Kim et al. (2022), Blood KL-6 predicts prognosis in primary Sjï¿½gren's syndrome-associated interstitial lung disease Scientific Reports, 12(1):5343.
PMID: 35351939
Species: Human
Sample Types: Conditioned Media

A Barilli et al. (2022), Immune-Mediated Inflammatory Responses of Alveolar Epithelial Cells: Implications for COVID-19 Lung Pathology Biomedicines, 10(3).
PMID: 35327420
Species: Human
Sample Types: Cell Culture Supernates

R Santarelli et al. (2022), 3,4-Dihydroxyphenylethanol (DPE or Hydroxytyrosol) Counteracts ERK1/2 and mTOR Activation, Pro-Inflammatory Cytokine Release, Autophagy and Mitophagy Reduction Mediated by Benzo[a]pyrene in Primary Human Colonic Epithelial Cells Pharmaceutics, 14(3).
PMID: 35336037
Species: Human
Sample Types: Serum

AS Bonavia et al. (2022), Resistin production does not affect outcomes in a mouse model of acute surgical sepsis PLoS ONE, 17(3):e0265241.
PMID: 35286340
Species: Human
Sample Types: Plasma

D Kruger et al. (2022), Pancreatic ductal adenocarcinoma: Prognostic indicators of advanced disease PLoS ONE, 17(1):e0262439.
PMID: 35020761
Species: Human
Sample Types: Cell Culture Supernates

Z Zhong et al. (2022), miR-132-3p Modulates DUSP9-Dependent p38/JNK Signaling Pathways to Enhance Inflammation in the Amnion Leading to Labor International Journal of Molecular Sciences, 23(3).
PMID: 35163786
Species: Human
Sample Types: Cell Culture Supernates

V Hennings et al. (2022), The presence of serum anti-SARS-CoV-2 IgA appears to protect primary health care workers from COVID-19 European Journal of Immunology, 0(0).
PMID: 35128644
Species: Human
Sample Types: Plasma

WY Wu et al. (2022), Pre-diagnostic levels of sVEGFR2, sTNFR2, sIL-2Ralpha and sIL-6R are associated with glioma risk: A nested case-control study of repeated samples Cancer Medicine, 0(0).
PMID: 35029050
Species: Human
Sample Types: Plasma

J Magalhães et al. (2022), Could Bone Biomarkers Predict Bone Turnover after Kidney Transplantation?-A Proof-of-Concept Study Journal of Clinical Medicine, 11(2).
PMID: 35054152
Species: Human
Sample Types: Cell Culture Supernates

JP Richardson et al. (2022), Candidalysins Are a New Family of Cytolytic Fungal Peptide Toxins MBio, 0(0):e0351021.
PMID: 35073742
Species: Human
Sample Types: Cell Culture Supernates

AM Dobri et al. (2022), Low-Concentrations of Fatty Acids Induce an Early Increase in IL-8 Levels in Normal Human Astrocytes Metabolites, 12(4).
PMID: 35448516
Species: Human
Sample Types: Serum

DC Zanin-Silv et al. (2022), Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients Arthritis Research Therapy, 2022;24(1):95.
PMID: 35488348
Species: Human
Sample Types: Serum

YH Choi et al. (2022), Natural antibody IgG levels are associated with HBeAg-positivity and seroconversion in chronic hepatitis B patients treated with entecavir Scientific Reports, 12(1):4382.
PMID: 35288624
Species: Human
Sample Types: Serum

FSL Sánchez et al. (2022), Endoglin and Other Angiogenesis Markers in Recurrent Varicose Veins Journal of personalized medicine, 12(4).
PMID: 35455644
Species: Human
Sample Types: Saliva

M Collin et al. (2022), Salivary biomarkers in children with juvenile idiopathic arthritis and healthy age-matched controls: a prospective observational study Scientific Reports, 12(1):3240.
PMID: 35217774
Species: Human
Sample Types: Serum

X García-Del et al. (2022), Molecular Biomarkers of Prognosis in Advanced Renal Cell Carcinoma Patients Treated With Pazopanib Plus Interferon Alpha (INF-2A) in a Phase I/II Study by the Spanish Oncology Genitourinary Group Clinical genitourinary cancer, 0(0).
PMID: 35428584
Species: Human
Sample Types: Plasma

S Hakki et al. (2022), Circulating Interleukin-6 and CD16 positive monocytes increase following angioplasty of an arteriovenous fistula Scientific Reports, 12(1):1427.
PMID: 35082332
Species: Human
Sample Types: Cell Culture Supernates

M Sakamoto et al. (2022), Dried human cultured epidermis accelerates wound healing in diabetic mouse skin defect wounds Scientific Reports, 12(1):3184.
PMID: 35210511
Species: Human
Sample Types: Plasma

GB Gonzales et al. (2022), The role of albumin and the extracellular matrix on the pathophysiology of oedema formation in severe malnutrition EBioMedicine, 79(0):103991.
PMID: 35398787
Species: Human
Sample Types: Cell Culture Supernates

T Gentinetta et al. (2022), Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Disease: Preclinical Evidence Journal of Clinical Medicine, 11(3).
PMID: 35160081
Species: Human
Sample Types: Cell Culture Supernates

S Song et al. (2022), EGFR/MET promotes hepatocellular carcinoma metastasis by stabilizing tumor cells and resisting to RTKs inhibitors in circulating tumor microemboli Cell Death Disease, 2022;13(4):351.
PMID: 35428350
Species: Human
Sample Types: Cell Culture Supernates

M Liu et al. (2022), RBMS1 promotes gastric cancer metastasis through autocrine IL-6/JAK2/STAT3 signaling Cell Death Disease, 2022;13(3):287.
PMID: 35361764
Species: Human
Sample Types: Plasma

H Ali et al. (2022), Association of significantly elevated plasma levels of NGAL and IGFBP4 in patients with diabetic nephropathy Bmc Nephrology, 23(1):64.
PMID: 35148702
Species: Human
Sample Types: Serum

TTU Nguyen et al. (2022), Serum VEGF-D level is correlated with renal dysfunction and proteinuria in patients with diabetic chronic kidney disease Medicine, 101(7):e28804.
PMID: 35363168
Species: Human
Sample Types: Plasma

A Li et al. (2022), Do urinary metals associate with the homeostasis of inflammatory mediators? Results from the perspective of inflammatory signaling in middle-aged and older adults Environment international, 163(0):107237.
PMID: 35429917
Species: Human
Sample Types: Cervicovaginal Fluid

D Chan et al. (2022), Microbial-driven preterm labour involves crosstalk between the innate and adaptive immune response Nature Communications, 13(1):975.
PMID: 35190561
Species: Human
Sample Types: Plasma

C Junqueira et al. (2022), FcgammaR-mediated SARS-CoV-2 infection of monocytes activates inflammation Nature, 0(0).
PMID: 35385861
Species: Human
Sample Types: Plasma

N Altet et al. (2022), Tobacco Smoking and Second-Hand Smoke Exposure Impact on Tuberculosis in Children Journal of Clinical Medicine, 11(7).
PMID: 35407608
Species: Human
Sample Types: CSF

A Longobardi et al. (2022), Cerebrospinal Fluid EV Concentration and Size Are Altered in Alzheimer's Disease and Dementia with Lewy Bodies Cells, 11(3).
PMID: 35159272
Species: Human
Sample Types: Plasma

Y Myojin et al. (2022), Interleukin-6 Is a Circulating Prognostic Biomarker for Hepatocellular Carcinoma Patients Treated with Combined Immunotherapy Cancers, 14(4).
PMID: 35205631
Species: Human
Sample Types: Plasma

M Huang et al. (2022), Circulating ADAMTS13 Levels Are Associated with an Increased Occurrence of Obstructive Sleep Apnea Disease Markers, 2022(0):1504137.
PMID: 35392493
Species: Human
Sample Types: Cell Culture Supernates

J Woo et al. (2022), Isatis tinctoria L. Leaf Extract Inhibits Replicative Senescence in Dermal Fibroblasts by Regulating mTOR-NF-kappaB-SASP Signaling Nutrients, 14(9).
PMID: 35565945
Species: Human
Sample Types: Serum

M Mathur et al. (2022), Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgG2 Monoclonal Antibody, in Healthy Volunteers Kidney international reports, 7(5):993-1003.
PMID: 35570983
Species: Human
Sample Types: Serum

T Takeda et al. (2022), Characteristics of the gut microbiota in women with premenstrual symptoms: A cross-sectional study PLoS ONE, 17(5):e0268466.
PMID: 35622782
Species: Human
Sample Types: Saliva

HN Kim (2022), Changes in salivary matrix metalloproteinase-3, -8, and -9 concentrations after 6ï¿½weeks of non-surgical periodontal therapy BMC Oral Health, 22(1):175.
PMID: 35562715
Species: Human
Sample Types: Cell Culture Supenates

NO Ponde et al. (2022), Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin The Journal of Biological Chemistry, 0(0):102419.
PMID: 36037968
Species: Human
Sample Types: Cell Culture Supernates

R Gonnella et al. (2022), Mechanisms of Sensitivity and Resistance of Primary Effusion Lymphoma to Dimethyl Fumarate (DMF) International Journal of Molecular Sciences, 23(12).
PMID: 35743211
Species: Human
Sample Types: Plasma

CJ Worby et al. (2022), Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women Nature Microbiology, 7(5):630-639.
PMID: 35505248
Species: Human
Sample Types: BALF

CYK Zhang et al. (2022), Utility of bile acids in large airway bronchial wash versus bronchoalveolar lavage as biomarkers of microaspiration in lung transplant recipients: a retrospective cohort study Respiratory Research, 23(1):219.
PMID: 36028826
Species: Human
Sample Types: Plasma

X Brands et al. (2022), Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patients PLoS ONE, 17(7):e0271637.
PMID: 35877767
Species: Human
Sample Types: Serum

S Sivasubram et al. (2022), Serum levels of matrix metalloproteinases as prognostic markers for severe dengue with plasma leakage Experimental and molecular pathology, 128(0):104821.
PMID: 35908616
Species: Human
Sample Types: Cell Culture Supernates

A Barilli et al. (2022), The JAK1/2 Inhibitor Baricitinib Mitigates the Spike-Induced Inflammatory Response of Immune and Endothelial Cells In Vitro Biomedicines, 10(9).
PMID: 36140425
Species: Human
Sample Types: Cell Culture Supernates

G Brawerman et al. (2022), DNA damage to beta cells in culture recapitulates features of senescent beta cells that accumulate in type 1 diabetes Molecular Metabolism, 0(0):101524.
PMID: 35660116
Species: Human
Sample Types: Cell Culture Supernates

A Anchan et al. (2022), Melanoma Mediated Disruption of Brain Endothelial Barrier Integrity Is Not Prevented by the Inhibition of Matrix Metalloproteinases and Proteases Biosensors, 12(8).
PMID: 36005056
Species: Human
Sample Types: Cell Culture Supernates

AJ Poe et al. (2022), Regulatory role of miR-146a in corneal epithelial wound healing via its inflammatory targets in human diabetic cornea The ocular surface, 25(0):92-100.
PMID: 35690236
Species: Human
Sample Types: Cell Culture Supernatants

V Mathieu et al. (2022), Amaryllidaceae Alkaloids Decrease the Proliferation, Invasion, and Secretion of Clinically Relevant Cytokines by Cultured Human Colon Cancer Cells Biomolecules, 12(9).
PMID: 36139106
Species: Human
Sample Types: Serum

JG Williams et al. (2022), Multi-omic characterization of pediatric ARDS via nasal brushings Respiratory Research, 23(1):181.
PMID: 35804409
Species: Human
Sample Types: Serum

C Lefeuvre et al. (2022), Analysis of hepatic fibrosis markers in the serum of chronic hepatitis B patients according to basal core promoter/precore mutants Oncogene, 12(1):10261.
PMID: 35715541
Species: Human
Sample Types: Plasma

T Azamor et al. (2022), Protective Immunity of COVID-19 Vaccination with ChAdOx1 nCoV-19 Following Previous SARS-CoV-2 Infection: A Humoral and Cellular Investigation Viruses, 14(9).
PMID: 36146723
Species: Human
Sample Types: Extracellular Vesicles

LE Martínez et al. (2022), Plasma extracellular vesicles bearing PD-L1, CD40, CD40L or TNF-RII are significantly reduced after treatment of AIDS-NHL Oncogene, 12(1):9185.
PMID: 35655072
Species: Human
Sample Types: Serum

R Wakiya et al. (2022), Effect of add-on hydroxychloroquine therapy on serum proinflammatory cytokine levels in patients with systemic lupus erythematosus Scientific Reports, 12(1):10175.
PMID: 35715525
Species: Human
Sample Types: Serum

D Kibirige et al. (2022), Clinical, metabolic, and immunological characterisation of adult Ugandan patients with new-onset diabetes and low vitamin D status BMC endocrine disorders, 22(1):230.
PMID: 36109715
Species: Human
Sample Types: Plasma

H Lu et al. (2022), Immediate outcome prognostic value of plasma factors in patients with acute ischemic stroke after intravenous thrombolytic treatment BMC neurology, 22(1):359.
PMID: 36127663
Species: Human
Sample Types: Plasma

M Skogstad et al. (2022), A Cease in Shift Work Reverses Arterial Stiffness but Increases Weight and Glycosylated Hemoglobin A 5-Month Follow-Up in Industry Oncogene, 9(6).
PMID: 35735819
Species: Human
Sample Types: Lung Perfusate

F Gori et al. (2022), Lung Biomolecular Profile and Function of Grafts from Donors after Cardiocirculatory Death with Prolonged Donor Warm Ischemia Time Oncogene, 11(11).
PMID: 35683455
Species: Human
Sample Types: Serum

TN Mann et al. (2022), Evaluation of host biomarkers for monitoring treatment response in spinal tuberculosis: A 12-month cohort study Cytokine, 157(0):155944.
PMID: 35717881
Species: Human
Sample Types: Cell Culture Supernates

F Wu et al. (2022), CD96 Downregulation Promotes the Immune Response of CD4 T Cells and Associates with Ankylosing Spondylitis Oncogene, 2022(0):3946754.
PMID: 35769669
Species: Human
Sample Types: Plasma

Y Kwon et al. (2022), Cytokine Profile at Diagnosis Affecting Trough Concentration of Infliximab in Pediatric Crohn's Disease Biomedicines, 10(10).
PMID: 36289634
Species: Human
Sample Types: Plasma

L Mansouri et al. (2022), "Role of kidney function and concentrations of BAFF, sPD-L1 and sCD25 on mortality in hospitalized patients with COVID-19" Bmc Nephrology, 23(1):299.
PMID: 36056305
Species: Human
Sample Types: Serum

AA Duizendstr et al. (2022), Minimal Development of Liver Fibrosis in Adult Tolerant Liver Transplant Recipients Late After Immunosuppressive Drug Weaning and Transplantation Transplantation Proceedings, 0(0).
PMID: 36100485
Species: Human
Sample Types: Cell Culture Supernates

C Andrade Al et al. (2022), The impact of gender and peripheral blood parameters on the characteristics of L-PRF membranes Journal of oral biology and craniofacial research, 12(6):753-759.
PMID: 36118143
Species: Human
Sample Types: Serum

IE Ennin et al. (2022), White Blood Cell Count and Serum Cytokine Profile in Tropical Hardwood Workers in Kumasi Oncogene, 2022(0):8245717.
PMID: 35795404
Species: Human
Sample Types: Nasal Fluid

G Arias-Brav et al. (2022), Overnutrition, Nasopharyngeal Pathogenic Bacteria and Proinflammatory Cytokines in Infants with Viral Lower Respiratory Tract Infections International Journal of Environmental Research and Public Health, 19(14).
PMID: 35886632
Species: Human
Sample Types: Amniotic Fluid

JH Jang et al. (2022), The association between amniotic fluid-derived inflammatory mediators and the risk of retinopathy of prematurity Oncogene, 101(27):e29368.
PMID: 35801764
Species: Human
Sample Types: Nasal Fluid

E De Corso et al. (2022), Sinonasal Biomarkers Defining Type 2-High and Type 2-Low Inflammation in Chronic Rhinosinusitis with Nasal Polyps Journal of personalized medicine, 12(8).
PMID: 36013200
Species: Human
Sample Types: Plasma

J Hernandez et al. (2022), Cocaine use associated gut permeability and microbial translocation in people living with HIV in the Miami Adult Study on HIV (MASH) cohort PLoS ONE, 17(10):e0275675.
PMID: 36215260
Species: Human
Sample Types: Cell Culture Supernates

JS Heo (2022), Selenium-Stimulated Exosomes Enhance Wound Healing by Modulating Inflammation and Angiogenesis International Journal of Molecular Sciences, 23(19).
PMID: 36232844
Species: Human
Sample Types: Cell Culture Supernates

C Fernández- et al. (2022), The Giardial Arginine Deiminase Participates in Giardia-Host Immunomodulation in a Structure-Dependent Fashion via Toll-like Receptors International Journal of Molecular Sciences, 23(19).
PMID: 36232855
Species: Human
Sample Types: Plasma

JN López-Cano et al. (2022), The Role of Fatty Acid-Binding Protein 4 in the Characterization of Atrial Fibrillation and the Prediction of Outcomes after Catheter Ablation International Journal of Molecular Sciences, 23(19).
PMID: 36232410
Species: Human
Sample Types: Plasma

J Bosanac et al. (2022), HFpEF and Atrial Fibrillation: The Enigmatic Interplay of Dysmetabolism, Biomarkers, and Vascular Endothelial Dysfunction Disease Markers, 2022(0):9539676.
PMID: 36330203
Species: Human
Sample Types: Plasma

CR McDonald et al. (2022), Sex as a determinant of disease severity and clinical outcome in febrile children under five presenting to a regional referral hospital in Uganda PLoS ONE, 17(10):e0276234.
PMID: 36269702
Species: Human
Sample Types: Plasma

ND Mehta et al. (2022), Inflammation, Amygdala-Ventromedial Prefrontal Functional Connectivity and Symptoms of Anxiety and PTSD in African American Women Recruited from an Inner-City Hospital: Preliminary Results Brain, Behavior, and Immunity, 105(0):122-130.
PMID: 35772683
Species: Human
Sample Types: Cell Culture Supernates

W Lenga Ma B et al. (2022), Receptor for Advanced Glycation End-Products Promotes Activation of Alveolar Macrophages through the NLRP3 Inflammasome/TXNIP Axis in Acute Lung Injury International Journal of Molecular Sciences, 23(19).
PMID: 36232959
Species: Human
Sample Types: Plasma

X Qiao et al. (2022), Biological Effects of Intravenous Vitamin C on Neutrophil Extracellular Traps and the Endothelial Glycocalyx in Patients with Sepsis-Induced ARDS Nutrients, 14(20).
PMID: 36297099
Species: Human
Sample Types: Serum

M Reina-Cout et al. (2022), Urinary Cysteinyl Leukotrienes as Biomarkers of Endothelial Activation, Inflammation and Oxidative Stress and Their Relationship with Organ Dysfunction in Human Septic Shock Biomedicines, 10(11).
PMID: 36359365
Species: Human
Sample Types: Plasma

CR McDonald et al. (2022), Immune and endothelial activation markers and risk stratification of childhood pneumonia in Uganda: A secondary analysis of a prospective cohort study Oncogene, 19(7):e1004057.
PMID: 35830474
Species: Human
Sample Types: Breast Milk

F Trofin et al. (2022), Cytokines and Chemokines in Breastmilk of SARS-CoV-2 Infected or COVID-19 Vaccinated Mothers Vaccines, 10(12).
PMID: 36560410
Species: Human
Sample Types: Plasma

R Zhang et al. (2022), Proteomics profiles of blood glucose-related proteins involved in a Chinese longevity cohort Clinical Proteomics, 19(1):45.
PMID: 36463101
Species: Human
Sample Types: Plasma

H Sun et al. (2022), Increasing circulating ESM-1 and adhesion molecules are associated with earlystage atherosclerosis in OSA patients:A cross-sectional study Sleep medicine, 98(0):114-120.
PMID: 35830780
Species: Human
Sample Types: Serum

X Ying et al. (2022), Comparison of Pulmonary Function and Inflammation in Children/Adolescents with New-Onset Asthma with Different Adiposity Statuses Nutrients, 14(14).
PMID: 35889925
Species: Human
Sample Types: Cell Culture Supernates

E Fiorino et al. (2022), Integrated Antitumor Activities of Cellular Immunotherapy with CIK Lymphocytes and Interferons against KIT/PDGFRA Wild Type GIST International Journal of Molecular Sciences, 23(18).
PMID: 36142281
Species: Human
Sample Types: BALF

K Wang et al. (2022), Lumican is elevated in the lung in human and experimental acute respiratory distress syndrome and promotes early fibrotic responses to lung injury Journal of Translational Medicine, 20(1):392.
PMID: 36059026
Species: Human
Sample Types: Serum

ML Sarangam et al. (2022), Intestinal Injury Biomarkers Predict Mortality in Pediatric Severe Malaria MBio, 0(0):e0132522.
PMID: 36069443
Species: Human
Sample Types: Plasma

V Folope et al. (2022), Evaluation of a Supervised Adapted Physical Activity Program Associated or Not with Oral Supplementation with Arginine and Leucine in Subjects with Obesity and Metabolic Syndrome: A Randomized Controlled Trial Nutrients, 14(18).
PMID: 36145083
Species: Human
Sample Types: Tissue Homogenates

F Real et al. (2022), S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo Nature Communications, 13(1):5956.
PMID: 36220814
Species: Human
Sample Types: Cell Culture Supernates

C Engelmann et al. (2022), Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1 Cell Death Disease, 2022;13(10):892.
PMID: 36270981
Species: Human
Sample Types: Vitreous Humor

K Suzuki et al. (2022), Clinical significance of serum and vitreous soluble interleukin-2 receptor in patients with intraocular lymphoma BMC ophthalmology, 22(1):428.
PMID: 36357882
Species: Human
Sample Types: Plasma

E Winheim et al. (2022), Distinct and dynamic activation profiles of circulating dendritic cells and monocytes in mild COVID-19 and after yellow fever vaccination European Journal of Immunology, 0(0).
PMID: 36404054
Species: Human
Sample Types: Plasma

I Asante et al. (2022), Alterations in Renin-Angiotensin System (RAS) Peptide Levels in Patients with HIV Metabolites, 13(1).
PMID: 36676986
Species: Human
Sample Types: Serum

M Robin et al. (2021), Ruxolitinib before allogeneic hematopoietic transplantation in patients with myelofibrosis on behalf SFGM-TC and FIM groups Bone marrow transplantation, 0(0).
PMID: 33767402
Species: Human
Sample Types: Serum

M Macías et al. (2021), Characterization of the perioperative changes of exosomal immune-related cytokines induced by prostatectomy in early-stage prostate cancer patients Cytokine, 141(0):155471.
PMID: 33607398
Species: Human
Sample Types: Saliva

MHH Withanage et al. (2021), Dataset-chemokines, cytokines, and biomarkers in the saliva of children with Sjï¿½gren's syndrome Data in Brief, 36(0):107139.
PMID: 34095386
Species: Human
Sample Types: Tissue Homogenates

DK Kim et al. (2021), Effect of obstructive sleep apnea on immunity in cases of chronic rhinosinusitis with nasal polyp Clinical and experimental otorhinolaryngology, 0(0).
PMID: 33541034
Species: Human
Sample Types: Cell Culture Supernates

BM Jackson-Th et al. (2021), Prospective Assessment of SARS-CoV-2 Seroconversion (PASS) study: an observational cohort study of SARS-CoV-2 infection and vaccination in healthcare workers BMC infectious diseases, 21(1):544.
PMID: 34107889
Species: Human
Sample Types: Cell Culture Supernates

A Caner (2021), Toxoplasma gondii could have a possible role in the cancer mechanism by modulating the host's cell response Acta tropica, 220(0):105966.
PMID: 34023305
Species: Human
Sample Types: Plasma

SH Ahn et al. (2021), Changes in plasma sclerostin level associated with use of a medium cut-off dialyzer in end-stage renal disease Kidney research and clinical practice, 40(1):120-134.
PMID: 33745263
Species: Squirrel
Sample Types: Tissue Homogenates

SM Logan et al. (2021), Markers of tissue remodeling and inflammation in the white and brown adipose tissues of a model hibernator Cellular Signalling, 82(0):109975.
PMID: 33711429
Species: Human
Sample Types: Plasma

MM Brunton-O' et al. (2021), A combined biomarker approach for characterising extracellular matrix profiles in acute myocardial infarction Scientific Reports, 11(1):12705.
PMID: 34135421
Species: Human
Sample Types: Serum

FA Alnajjar et al. (2021), The Expression and Function of Metastases Associated Lung Adenocarcinoma Transcript-1 Long Non-Coding RNA in Subchondral Bone and Osteoblasts from Patients with Osteoarthritis Cells, 10(4).
PMID: 33916321
Species: Human
Sample Types: Cell Culture Supernates

CMA Maia et al. (2021), Yeast-Host Interactions: Anadenanthera colubrina Modulates Virulence Factors of C. albicans and Inflammatory Response In Vitro Frontiers in Pharmacology, 12(0):629778.
PMID: 34168555
Species: Human
Sample Types: Serum

E Rutkowska et al. (2021), Cytokines and Leukocytes Subpopulations Profile in SARS-CoV-2 Patients Depending on the CT Score Severity Viruses, 13(5).
PMID: 34064802
Species: Human
Sample Types: Serum

A Gomez-Brou et al. (2021), Characterization of Macrophages and Osteoclasts in the Osteosarcoma Tumor Microenvironment at Diagnosis: New Perspective for Osteosarcoma Treatment? Cancers, 13(3).
PMID: 33498676
Species: Human
Sample Types: Cell Culture Supernates

R Gonnella et al. (2021), IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation Biomedicines, 9(2).
PMID: 33513694
Species: Human
Sample Types: Cell Culture Supernates

J Javadi et al. (2021), Syndecan-1 Overexpressing Mesothelioma Cells Inhibit Proliferation, Wound Healing, and Tube Formation of Endothelial Cells Cancers, 13(4).
PMID: 33562126
Species: Human
Sample Types: Plasma

MA Dragon-Dur et al. (2021), Differential association between inflammatory cytokines and multiorgan dysfunction in COVID-19 patients with obesity PLoS ONE, 16(5):e0252026.
PMID: 34038475
Species: Human
Sample Types: Whole Blood

KR Xulu et al. (2021), Antiplatelet Therapy Combined with Anastrozole Induces Features of Partial EMT in Breast Cancer Cells and Fails to Mitigate Breast-Cancer Induced Hypercoagulation International Journal of Molecular Sciences, 22(8).
PMID: 33923802
Species: Human
Sample Types: Serum

Z Lin et al. (2021), Evaluation of a Three-Marker Panel for the Detection of Uveal Melanoma Metastases: A Single-Center Retrospective Analysis Cancers, 13(10).
PMID: 34070192
Species: Human
Sample Types: Serum

H Abrahamsso et al. (2021), Sex disparities in vitamin D status and the impact on systemic inflammation and survival in rectal cancer BMC Cancer, 21(1):535.
PMID: 33975557
S Nabweyambo et al. (2021), Circulating levels of angiogenic factors and their association with preeclampsia among pregnant women at Mulago National Referral Hospital in Uganda PLoS ONE, 16(5):e0251227.
PMID: 34010327
Species: Human
Sample Types: Serum

CM Manyelo et al. (2021), Serum and cerebrospinal fluid host proteins indicate stroke in children with tuberculous meningitis PLoS ONE, 16(4):e0250944.
PMID: 33930055
Species: Human
Sample Types: Serum

KW Choi et al. (2021), Predictive inflammatory biomarkers for change in suicidal ideation in major depressive disorder and panic disorder: A 12-week follow-up study Journal of psychiatric research, 133(0):73-81.
PMID: 33310645
Species: Human
Sample Types: Serum

Y Tan et al. (2021), Integrating longitudinal clinical laboratory tests with targeted proteomic and transcriptomic analyses reveal the landscape of host responses in COVID-19 Cell Discovery, 7(1):42.
PMID: 34103487
Species: Human
Sample Types: Serum

M Signore et al. (2021), Diagnostic and prognostic potential of the proteomic profiling of serum-derived extracellular vesicles in prostate cancer Cell Death Disease, 2021;12(7):636.
PMID: 34155195
Species: Human
Sample Types: Serum

P Soret et al. (2021), A new molecular classification to drive precision treatment strategies in primary Sjï¿½gren's syndrome Nature Communications, 12(1):3523.
PMID: 34112769
Species: Human
Sample Types: Cell Culture Supernates

A Figiel-Dab et al. (2021), Neurogenic and Neuroprotective Potential of Stem/Stromal Cells Derived from Adipose Tissue Cells, 10(6).
PMID: 34208414
Species: Human
Sample Types: Plasma

Q Lv et al. (2021), Increased levels of VCAM-1 is associated with higher occurrence of coronary artery disease in adults with moderate to severe obstructive sleep apnea Sleep medicine, 85(0):131-137.
PMID: 34325382
Species: Human
Sample Types: Plasma

A Frimpong et al. (2021), Elevated Levels of the Endothelial Molecules ICAM-1, VEGF-A, and VEGFR2 in Microscopic Asymptomatic Malaria Open forum infectious diseases, 8(7):ofab302.
PMID: 34277886
Species: Human
Sample Types: Serum

SS Ahn et al. (2021), Serum adipokine profiles in patients with microscopic polyangiitis and granulomatosis with polyangiitis: An exploratory analysis PLoS ONE, 16(7):e0254226.
PMID: 34242326
Species: Human
Sample Types: Plasma

K ?uczkowska et al. (2021), The Potential Role of Proinflammatory Cytokines and Complement Components in the Development of Drug-Induced Neuropathy in Patients with Multiple Myeloma Journal of Clinical Medicine, 10(19).
PMID: 34640602
Species: Human
Sample Types: Plasma

S De Biasi et al. (2021), Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection Nature Communications, 12(1):4677.
PMID: 34326336
Species: Human
Sample Types: Aqueous Humor

JW Kwon et al. (2021), Aqueous humor analyses of diabetic macular edema patients with subretinal fluid Scientific Reports, 11(1):20985.
PMID: 34697354
Species: Human
Sample Types: Cell Culture Supernates

M Grill et al. (2021), Vocal Fold Fibroblasts in Reinke's Edema Show Alterations Involved in Extracellular Matrix Production, Cytokine Response and Cell Cycle Control Biomedicines, 9(7).
PMID: 34206882
Species: Human
Sample Types: Cell Culture Supernates

JK Park et al. (2021), Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis Arthritis Research Therapy, 2021;23(1):177.
PMID: 34225810
Species: Human
Sample Types: Aqueous Humor

J Wang et al. (2021), Potential effects of angiogenesis-related factors on the severity of APAC and surgical outcomes of trabeculectomy BMC ophthalmology, 21(1):297.
PMID: 34384366
Species: Human
Sample Types: Tissue Homogenates

LA Kotze et al. (2021), Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis mSphere, 0(0):e0055221.
PMID: 34287004
Species: Human
Sample Types: Cell Culture Supernates

A Musa et al. (2021), Plantaricin NC8 alphabeta prevents Staphylococcus aureus-mediated cytotoxicity and inflammatory responses of human keratinocytes Scientific Reports, 11(1):12514.
PMID: 34131160
Species: Human
Sample Types: Cell Culture Supernates

R Serrano et al. (2021), Monocyte-dependent co-stimulation of cytokine induction in human gammadelta T cells by TLR8 RNA ligands Scientific Reports, 11(1):15231.
PMID: 34315922
Species: Human
Sample Types: Serum

M Zajkowska et al. (2021), Eotaxins and Their Receptor as Biomarkers of Colorectal Cancer Journal of Clinical Medicine, 10(12).
PMID: 34204490
Species: Human
Sample Types: Plasma

P Simons et al. (2021), Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease Viruses, 13(8).
PMID: 34452463
Species: Human
Sample Types: Saliva

Y Xie et al. (2021), Specific Cytokine Profiles Predict the Severity of Influenza A Pneumonia: A Prospectively Multicenter Pilot Study BioMed Research International, 2021(0):9533044.
PMID: 34692846
Species: Human
Sample Types: Plasma

A Alterki et al. (2021), The Rise of IGFBP4 in People with Obstructive Sleep Apnea and Multilevel Sleep Surgery Recovers Its Basal Levels Disease Markers, 2021(0):1219593.
PMID: 34646401
Species: Human
Sample Types: Plasma

C Junqueira et al. (2021), SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release Research square, 0(0).
PMID: 34401873
Species: Human
Sample Types: Plasma

M Nguyen et al. (2021), High plasma concentration of non-esterified polyunsaturated fatty acids is a specific feature of severe COVID-19 pneumonia Scientific Reports, 11(1):10824.
PMID: 34031519
Species: Human
Sample Types: Nasal Lavage Fluid

B Monel et al. (2021), Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study EBioMedicine, 73(0):103637.
PMID: 34678613
Species: Human
Sample Types: Plasma

N Pavan Kuma et al. (2021), Effect of BCG vaccination on proinflammatory responses in elderly individuals Science Advances, 7(32).
PMID: 34348897
Species: Human
Sample Types: Plasma

N Yatim et al. (2021), Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection Science Advances, 7(34).
PMID: 34407944
Species: Human
Sample Types: Cell Culture Supernates

A Naik et al. (2021), Cancer testis antigen PRAME: An anti-cancer target with immunomodulatory potential Journal of Cellular and Molecular Medicine, 0(0).
PMID: 34612587
Species: Human
Sample Types: Serum

CM Villanueva et al. (2021), Exposure to widespread drinking water chemicals, blood inflammation markers, and colorectal cancer Environment international, 157(0):106873.
PMID: 34543938
Species: Human
Sample Types: Plasma

F Schinzari et al. (2021), Variable Changes of Circulating ANGPTL3 and ANGPTL4 in Different Obese Phenotypes: Relationship with Vasodilator Dysfunction Biomedicines, 9(8).
PMID: 34440242
Species: Human
Sample Types: Cancer on Chip

JH Kim et al. (2021), Establishment of Three-Dimensional Bioprinted Bladder Cancer-on-a-Chip with a Microfluidic System Using Bacillus Calmette-Guï¿½rin International Journal of Molecular Sciences, 22(16).
PMID: 34445591
Species: Human
Sample Types: Urine

MF Mello et al. (2021), Urinary extracellular matrix proteins as predictors of the severity of ureteropelvic junction obstruction in children Journal of pediatric urology, 0(0).
PMID: 33863647
Species: Human
Sample Types: Cell Culture Supernates

IS Grønningsæ et al. (2021), Effects of the Autophagy-Inhibiting Agent Chloroquine on Acute Myeloid Leukemia Cells; Characterization of Patient Heterogeneity Journal of personalized medicine, 11(8).
PMID: 34442423
Species: Human
Sample Types: Cell Culture Supernates

R Lepzien et al. (2021), Pulmonary and blood dendritic cells from sarcoidosis patients more potently induce IFNgamma-producing Th1 cells compared with monocytes Journal of leukocyte biology, 0(0).
PMID: 34431542
Species: Human
Sample Types: CSF

WC Ziai et al. (2021), Early Inflammatory Cytokine Expression in Cerebrospinal Fluid of Patients with Spontaneous Intraventricular Hemorrhage Biomolecules, 11(8).
PMID: 34439789
Species: Human
Sample Types: Serum

F Hoel et al. (2021), A map of metabolic phenotypes in patients with myalgic encephalomyelitis/chronic fatigue syndrome JCI Insight, 6(16).
PMID: 34423789
Species: Human
Sample Types: Plasma

E Merlini et al. (2021), Predictors of low ovarian reserve in cART-treated women living with HIV Medicine, 100(39):e27157.
PMID: 34596114
Species: Human
Sample Types: Urine

J Udzik et al. (2021), Assessment and Prognosis in CSA-AKI Using Novel Kidney Injury Biomarkers: A Prospective Observational Study Biology, 10(9).
PMID: 34571700
Species: Human

Z Tang et al. (2021), Effects of Caloric Restriction and Rope-Skipping Exercise on Cardiometabolic Health: A Pilot Randomized Controlled Trial in Young Adults Nutrients, 13(9).
PMID: 34579097
Species: Human
Sample Types: Plasma

N Smith et al. (2021), Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection Nature Immunology, 0(0).
PMID: 34471264
Species: Human
Sample Types: Cell Culture Supernates

SP Korpela et al. (2021), Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response Journal of Translational Medicine, 19(1):43.
PMID: 33485341
Species: Human
Sample Types: Organoids

J Aguado et al. (2021), Inhibition of the cGAS-STING pathway ameliorates the premature senescence hallmarks of Ataxia-Telangiectasia brain organoids Aging Cell, 0(0):e13468.
PMID: 34459078
Species: Human
Sample Types: BALF

DM Kim et al. (2021), Enhanced eosinophil-mediated inflammation associated with antibody and complement-dependent pneumonic insults in critical COVID-19 Cell Reports, 0(0):109798.
PMID: 34587481
Species: Human
Sample Types: Serum

J Youngs et al. (2021), Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients PloS Pathogens, 17(9):e1009804.
PMID: 34529726
Species: Human
Sample Types: Cell Culture Supernates

A Pirosa et al. (2021), Modeling In Vitro Osteoarthritis Phenotypes in a Vascularized Bone Model Based on a Bone-Marrow Derived Mesenchymal Cell Line and Endothelial Cells International Journal of Molecular Sciences, 22(17).
PMID: 34502489
Species: Human
Sample Types: Cell Culture Supernates

H Cederkvist et al. (2021), Identification and characterization of a novel glutaminase inhibitor FEBS Open Bio, 0(0).
PMID: 34698439
Species: Human
Sample Types: Tears

MA Koduri et al. (2021), Differential expression of tear film cytokines in Stevens-Johnson syndrome patients and comparative review of literature Scientific Reports, 11(1):18433.
PMID: 34531438
Species: Human
Sample Types: Serum

M Truyens et al. (2021), Prevalence of Fatigue and Unrecognized Depression in Patients with Inflammatory Bowel Disease in Remission under Immunosuppressants and Biologicals Journal of Clinical Medicine, 10(18).
PMID: 34575218
Species: Human
Sample Types: Serum

J Song et al. (2021), A panel of selected serum protein biomarkers for the detection of aggressive prostate cancer Theranostics, 11(13):6214-6224.
PMID: 33995654
Species: Human
Sample Types: Plasma

BHY Gibson et al. (2021), Plasmin drives burn-induced systemic inflammatory response syndrome JCI Insight, 6(23).
PMID: 34877937
Species: Human
Sample Types: Plasma

R Neto et al. (2021), Low bone turnover is associated with plain X-ray vascular calcification in predialysis patients PLoS ONE, 16(10):e0258284.
PMID: 34644326
Species: Human
Sample Types: Cell Culture Supernates

R Sharma et al. (2021), Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model Nature Communications, 12(1):7293.
PMID: 34911940
Species: Human
Sample Types: Plasma

R Gamberale et al. (2021), Study protocol: understanding the pathophysiologic mechanisms underlying delirium in older people undergoing hip fracture surgery BMC geriatrics, 21(1):633.
PMID: 34736422
Species: Human
Sample Types: Cell Culture Supernates

HE Rodel et al. (2021), Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response Frontiers in Microbiology, 12(0):757134.
PMID: 34925266
Species: Human
Sample Types: Serum

T Gajewski et al. (2021), Severe COVID-19 infection is associated with aberrant cytokine production by infected lung epithelial cells rather than by systemic immune dysfunction Research square, 0(0).
PMID: 34845442
Species: Human
Sample Types: Cell Culture Supernates

Y Gao et al. (2021), Systems biological assessment of altered cytokine responses to bacteria and fungi reveals impaired immune functionality in schizophrenia Molecular Psychiatry, 0(0).
PMID: 34728799
Species: Human
Sample Types: Plasma

V Tran et al. (2021), The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy EBioMedicine, 73(0):103683.
PMID: 34758414
Species: Human
Sample Types: Exosomes

J Javadi et al. (2021), Diagnostic and Prognostic Utility of the Extracellular Vesicles Subpopulations Present in Pleural Effusion Biomolecules, 11(11).
PMID: 34827604
Species: Human
Sample Types: Cell Culture Supernates

QT Phan et al. (2021), The Globular C1q Receptor Is Required for Epidermal Growth Factor Receptor Signaling during Candida albicans Infection MBio, 0(0):e0271621.
PMID: 34724825
Species: Human
Sample Types: Serum

DL Hill et al. (2021), Impaired HA-specific T follicular helper cell and antibody responses to influenza vaccination are linked to inflammation in humans Elife, 10(0).
PMID: 34726156
Species: Human
Sample Types: Vaginal Lavage Fluid

P Sobia et al. (2021), Higher mucosal antibody concentrations in women with genital tract inflammation Scientific Reports, 11(1):23514.
PMID: 34873252
Species: Human
Sample Types: Serum

F Hong et al. (2021), Predictive role of endothelial cell activation in cytokine release syndrome after chimeric antigen receptor T cell therapy for acute lymphoblastic leukaemia Journal of Cellular and Molecular Medicine, 0(0).
PMID: 34734474
Species: Human
Sample Types: Cell Culture Supernates

I Dietrich et al. (2021), Differential cytokine expression in direct and indirect co-culture of islets and mesenchymal stromal cells Cytokine, 150(0):155779.
PMID: 34923221
Species: Human
Sample Types: Plasma

S Ashrafzade et al. (2021), Role of immune mediators in predicting hospitalization of SARS-CoV-2 positive patients Cytokine, 150(0):155790.
PMID: 34991059
Species: Human
Sample Types: Whole Blood

A Rajamanick et al. (2021), Effect of SARS-CoV-2 seropositivity on antigen - specific cytokine and chemokine responses in latent tuberculosis Cytokine, 150(0):155785.
PMID: 34933240
Species: Human
Sample Types: Cell Culture Supernates

K Chaumonnot et al. (2021), The HSP GRP94 interacts with macrophage intracellular complement C3 and impacts M2 profile during ER stress Cell Death Disease, 2021;12(1):114.
PMID: 33483465
Species: Human
Sample Types: Amniotic Fluid

J Bae et al. (2021), Comparison between Cervical Ureaplasma spp. Colonization and the Intensity of Inflammatory Mediators in the Amniotic Fluid Retrieved during Cesarean Delivery in Preterm Birth International Journal of Environmental Research and Public Health, 19(1).
PMID: 35010366
Species: Human
Sample Types: Serum

A Curatola et al. (2021), Cytokine Response to SARS-CoV-2 Infection in Children Viruses, 13(9).
PMID: 34578450
Species: Human
Sample Types: Cell Culture Supernates

M Dymowska et al. (2021), Interaction between Macrophages and Human Mesenchymal Stromal Cells Derived from Bone Marrow and Wharton's Jelly-A Comparative Study Pharmaceutics, 13(11).
PMID: 34834238
Species: Human
Sample Types: Cell Culture Supernates

M Dudau et al. (2021), A Fatty Acid Fraction Purified From Sea Buckthorn Seed Oil Has Regenerative Properties on Normal Skin Cells Frontiers in Pharmacology, 12(0):737571.
PMID: 34712136
Species: Human
Sample Types: Serum

S Meltzer et al. (2021), The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer British Journal of Cancer, 0(0).
PMID: 33837301
Species: Human
Sample Types: Plasma

S Li et al. (2021), Alteration of immune profiles is associated with pulmonary function and symptoms in patients with chronic obstructive pulmonary disease Molecular Medicine Reports, 24(5).
PMID: 34435653
Species: Human
Sample Types: Serum

T Yoon et al. (2021), Predictive Ability of Serum IL-27 Level for Assessing Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Mediators of Inflammation, 2021(0):6668884.
PMID: 34335091
Species: Human
Sample Types: Cell Culture Supernates

JD Hywood et al. (2021), Induced endothelial cells from peripheral arterial disease patients and neonatal fibroblasts have comparable angiogenic properties PLoS ONE, 16(8):e0255075.
PMID: 34375370
Species: Human
Sample Types: Plasma

SM Koh et al. (2020), Elevated plasma and synovial fluid interleukin-8 and interleukin-18 may be associated with the pathogenesis of knee osteoarthritis Knee, 0(0).
PMID: 31917106
Species: Human
Sample Types: Plasma

XY Lv et al. (2020), Rifaximin improves survival in cirrhotic patients with refractory ascites: A real-world study World J. Gastroenterol., 26(2):199-218.
PMID: 31988585
Species: Human
Sample Types: Plasma

N Ziliotto et al. (2020), Expression profiles of the internal jugular and saphenous veins: Focus on hemostasis genes Thromb. Res., 191(0):113-124.
PMID: 32438216
Species: Human
Sample Types: Serum

N Ghosh et al. (2020), Metabolomic fingerprinting and systemic inflammatory profiling of asthma COPD overlap (ACO) Respir. Res., 21(1):126.
PMID: 32448302
Species: Human
Sample Types: Whole Cell

JW Shin et al. (2020), Resveratrol Inhibits Particulate Matter-Induced Inflammatory Responses in Human Keratinocytes Int J Mol Sci, 21(10).
PMID: 32414118
Species: Human
Sample Types: Cell Culture Supernates

I Beltrán He et al. (2020), The Potential of Nanobody-Targeted Photodynamic Therapy to Trigger Immune Responses Cancers (Basel), 12(4).
PMID: 32326519
Species: Human

M Martin-Fer et al. (2020), Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions Cell Rep, 31(6):107633.
PMID: 32402279
Species: Human
Sample Types: Cell Culture Supernates

B Shrestha et al. (2020), Human CD83-targeted chimeric antigen receptor T cells prevent and treat graft-versus-host disease J. Clin. Invest., 0(0).
PMID: 32437331
Species: Human
Sample Types: Cell Culture Supernates

M Silasi et al. (2020), Human Chorionic Gonadotropin modulates CXCL10 Expression through Histone Methylation in human decidua Sci Rep, 10(1):5785.
PMID: 32238853
Species: Human
Sample Types: Whole Cells

Z El Ali et al. (2020), Therapeutic effects of CO-releaser/Nrf2 activator hybrids (HYCOs) in the treatment of skin wound, psoriasis and multiple sclerosis Redox Biol, 34(0):101521.
PMID: 32335359
Species: Human
Sample Types: Serum

C Reiterer et al. (2020), Mannitol and renal graft injury in patients undergoing deceased donor renal transplantation - a randomized controlled clinical trial BMC Nephrol, 21(1):307.
PMID: 32723374
Species: Human
Sample Types: Tissue Culture Supernates

J Jamal et al. (2020), Modulation of the mechanical responses of synovial fibroblasts by osteoarthritis-associated inflammatory stressors Int. J. Biochem. Cell Biol., 126(0):105800.
PMID: 32673644
Species: Human
Sample Types: Cell Culture Supernates

P Borilova L et al. (2020), Interleukin Gene Variability and Periodontal Bacteria in Patients with Generalized Aggressive Form of Periodontitis Int J Mol Sci, 21(13).
PMID: 32630798
Species: Human
Sample Types: Plasma

W Camu et al. (2020), Repeated 5-day cycles of low dose aldesleukin in amyotrophic lateral sclerosis (IMODALS): A phase 2a randomised, double-blind, placebo-controlled trial EBioMedicine, 0(0):102844.
PMID: 32651161
Species: Human
Sample Types: Serum

A Wiedemann et al. (2020), Long-lasting severe immune dysfunction in Ebola virus disease survivors Nat Commun, 11(1):3730.
PMID: 32709840
Species: Human
Sample Types: Cell Culture Supernates

K Ziegler et al. (2020), Chemical modification of pro-inflammatory proteins by peroxynitrite increases activation of TLR4 and NF-&kappaB: Implications for the health effects of air pollution and oxidative stress Redox Biol, 0(0):101581.
PMID: 32739154
Species: Human
Sample Types: Plasma

AM Georgescu et al. (2020), Evaluation of TNF-&alpha genetic polymorphisms as predictors for sepsis susceptibility and progression BMC Infect. Dis., 20(1):221.
PMID: 32171247
Species: Human
Sample Types: Cell Culture Supernates

R Ramadan et al. (2020), Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage Front Pharmacol, 11(0):212.
PMID: 32210810
Species: Human
Sample Types: Cell Culture Supernates

F Scheffel et al. (2020), Effective Activation of Human Antigen-Presenting Cells and Cytotoxic CD8+ T Cells by a Calcium Phosphate-Based Nanoparticle Vaccine Delivery System Vaccines (Basel), 8(1).
PMID: 32121590
Species: Human
Sample Types: Plasma

A Rajamanick et al. (2020), Helminth infection modulates systemic pro-inflammatory cytokines and chemokines implicated in type 2 diabetes mellitus pathogenesis PLoS Negl Trop Dis, 14(3):e0008101.
PMID: 32126084
Species: Human
Sample Types: Cell Culture Supernates

A Schmidt et al. (2020), Complex human adenoid tissue-based ex vivo culture systems reveal anti-inflammatory drug effects on germinal center T and B cells EBioMedicine, 53(0):102684.
PMID: 32114393
Species: Human
Sample Types: Plasma

X Cheng et al. (2020), Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection J. Clin. Invest., 0(0).
PMID: 32163375
Species: Human
Sample Types: Cell Culture Supernates

P van der Ze et al. (2020), Cytokines and Chemokines Are Detectable in Swivel-Derived Exhaled Breath Condensate (SEBC): A Pilot Study in Mechanically Ventilated Patients Dis. Markers, 2020(0):2696317.
PMID: 31998415
Species: Human
Sample Types: Plasma

CH Seol et al. (2020), The ratio of plasma angiopoietin-2 to angiopoietin-1 as a prognostic biomarker in patients with sepsis Cytokine, 129(0):155029.
PMID: 32059166
Species: Human
Sample Types: eye vitreous fluid

J Baek et al. (2020), Elevated M2 Macrophage Markers in Epiretinal Membranes With Ectopic Inner Foveal Layers Invest. Ophthalmol. Vis. Sci., 61(2):19.
PMID: 32053728
Species: Human
Sample Types: Saliva

LH Rubin et al. (2020), Remitted depression and cognition in HIV: The role of cortisol and inflammation Psychoneuroendocrinology, 114(0):104609.
PMID: 32062371
Species: Human
Sample Types: Plasma

M Kriss et al. (2020), Increased hepatic and circulating chemokine and osteopontin expression occurs early in human NAFLD development PLoS ONE, 15(7):e0236353.
PMID: 32730345
Species: Human
Sample Types: blood

CA Eide et al. (2020), Simultaneous kinase inhibition with ibrutinib and BCL2 inhibition with venetoclax offers a therapeutic strategy for acute myeloid leukemia Leukemia, 0(0).
PMID: 32094466
Species: Human
Sample Types: Cell Culture Supernates

M Carr et al. (2020), IKK&epsilon and TBK1 in diffuse large B-cell lymphoma: A possible mechanism of action of an IKK&epsilon/TBK1 inhibitor to repress NF-&kappaB and IL-10 signalling J. Cell. Mol. Med., 0(0).
PMID: 32858764
Species: Human
Sample Types: Whole Tissue

M Couselo-Se et al. (2020), Inflammatory and lipid regulation by cholinergic activity in epicardial stromal cells from patients who underwent open-heart surgery J. Cell. Mol. Med., 0(0).
PMID: 32767737
Species: Human
Sample Types: Plasma

E Meseguer et al. (2020), Osteopontin Predicts Three-Month Outcome in Stroke Patients Treated by Reperfusion Therapies Journal of Clinical Medicine, 9(12).
PMID: 33322093
JS Kim et al. (2020), Plasma Endocan as a Predictor of Cardiovascular Event in Patients with End-Stage Renal Disease on Hemodialysis Journal of Clinical Medicine, 9(12).
PMID: 33352837
Species: Human
Sample Types: Plasma

B Baumert et al. (2020), Repeated Application of Autologous Bone Marrow-Derived Lineage-Negative Stem/Progenitor Cells-Focus on Immunological Pathways in Patients with ALS Cells, 9(8).
PMID: 32752182
Species: Human
Sample Types: Serum

KW Choi et al. (2020), Predictive inflammatory biomarkers for change in suicidal ideation in major depressive disorder and panic disorder: A 12-week follow-up study Journal of psychiatric research, 133(0):73-81.
PMID: 33310645
Species: Human
Sample Types: Plasma

F Willenbroc et al. (2020), Circulating biomarkers and outcomes from a randomised phase 2 trial of gemcitabine versus capecitabine-based chemoradiotherapy for pancreatic cancer Br J Cancer, 0(0).
PMID: 33100327
Species: Human
Sample Types: Cell Culture Supernates

K Zielniok et al. (2020), Vadadustat, a HIF Prolyl Hydroxylase Inhibitor, Improves Immunomodulatory Properties of Human Mesenchymal Stromal Cells Cells, 9(11).
PMID: 33139632
Species: Human
Sample Types: Cell Culture Supernates

MJ Alhilali et al. (2020), Prognostic role of follicular fluid tumor necrosis factor alpha in the risk of early ovarian hyperstimulation syndrome BMC Pregnancy Childbirth, 20(1):691.
PMID: 33183268
Species: Human
Sample Types: Cell Culture Supernates

D Hortobagyi et al. (2020), In vitro mechanical vibration down-regulates pro-inflammatory and pro-fibrotic signaling in human vocal fold fibroblasts PLoS ONE, 15(11):e0241901.
PMID: 33211714
Species: Human
Sample Types: Cell Culture Supernates

MA Romeo et al. (2020), The cross-talk between STAT1/STAT3 and ROS up-regulates PD-L1 and promotes the release of pro-inflammatory/immune suppressive cytokines in primary monocytes infected by HHV-6B Virus Res, 292(0):198231.
PMID: 33207265
Species: Human
Sample Types: Serum

RA Ramadan et al. (2020), Identification of serum biomarker panel to differentiate malignant from benign thyroid nodules using multiplex bead assay J Egypt Natl Canc Inst, 32(1):35.
PMID: 32885338
Species: Human
Sample Types: Vitreous Humor

Q Wei et al. (2020), Proinflammatory and angiogenesis-related cytokines in vitreous samples of highly myopic patients Cytokine, 137(0):155308.
PMID: 33128924
Species: Human
Sample Types: Serum

H Yamaguchi et al. (2020), Elevated cytokine, chemokine, and growth and differentiation factor-15 levels in hemorrhagic shock and encephalopathy syndrome: A retrospective observational study Cytokine, 137(0):155324.
PMID: 33032108
Species: Human
Sample Types: Plasma

P Vetter et al. (2020), Daily Viral Kinetics and Innate and Adaptive Immune Response Assessment in COVID-19: a Case Series mSphere, 5(6).
PMID: 33177214
Species: Human
Sample Types: Cell Culture Supernates

WM Abdelwahab et al. (2020), Co-Adsorption of Synthetic Mincle Agonists and Antigen to Silica Nanoparticles for Enhanced Vaccine Activity: A Formulation Approach to Co-Delivery Int J Pharm, 0(0):120119.
PMID: 33249249
Species: Human
Sample Types: Cell Culture Supernates

M Nakamura et al. (2020), IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype Cancers (Basel), 12(11).
PMID: 33203088
Species: Human
Sample Types: Plasma

JJ Luxton et al. (2020), Temporal Telomere and DNA Damage Responses in the Space Radiation Environment Cell Rep, 33(10):108435.
PMID: 33242411
Species: Human
Sample Types: Plasma

M Rybtke et al. (2020), The extracellular polysaccharide matrix of Pseudomonas aeruginosa biofilms is a determinant of polymorphonuclear leukocyte responses Infect Immun, 0(0).
PMID: 33077623
Species: Human
Sample Types: Plasma

JB Gorin et al. (2020), Plasma FABP4 is associated with liver disease recovery during treatment-induced clearance of chronic HCV infection Sci Rep, 10(1):2081.
PMID: 32034167
Species: Human
Sample Types: Plasma

Z Nicole et al. (2020), Functional recovery in multiple sclerosis patients undergoing rehabilitation programs is associated with plasma levels of hemostasis inhibitors Mult Scler Relat Disord, 44(0):102319.
PMID: 32593960
Species: Human
Sample Types: Serum

M Altendahl et al. (2020), An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury PLoS ONE, 15(1):e0227835.
PMID: 31978079
Species: Mouse
Sample Types: Serum

J Lim et al. (2020), Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway Sci Adv, 6(16):eaba1334.
PMID: 32490200
Species: Human
Sample Types: Gingival Crevicular Fluid

F Valenzuela et al. (2020), Gingival Crevicular Fluid Zinc- and Aspartyl-Binding Protease Profile of Individuals with Moderate/Severe Atopic Dermatitis Biomolecules, 10(12).
PMID: 33255937
Species: Human
Sample Types: Whole Blood

H Batatinha et al. (2020), Probiotic supplementation in marathonists and its impact on lymphocyte population and function after a marathon: a randomized placebo-controlled double-blind study Sci Rep, 10(1):18777.
PMID: 33139757
Species: Human
Sample Types: Serum

MH Kaaij et al. (2020), Anti-IL-17A treatment reduces serum inflammatory, angiogenic and tissue remodeling biomarkers accompanied by less synovial high endothelial venules in peripheral spondyloarthritis Scientific Reports, 10(1):21094.
PMID: 33273664
Species: Human
Sample Types: Plasma

L Gibellini et al. (2020), Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID-19 pneumonia EMBO Mol Med, 0(0):e13001.
PMID: 33078545
Species: Human
Sample Types: CSF

XY Jiang et al. (2020), Co-expression of NMDA-receptor subunits NR1, NR2A, and NR2B in dysplastic neurons of teratomas in patients with paraneoplastic NMDA-receptor-encephalitis: a retrospective clinico-pathology study of 159 patients Acta Neuropathol Commun, 8(1):130.
PMID: 32771066
Species: Human
Sample Types: Tissue Homogenates

M Couselo-Se et al. (2020), Inflammatory and lipid regulation by cholinergic activity in epicardial stromal cells from patients who underwent open-heart surgery J. Cell. Mol. Med., 0(0).
PMID: 32767737
Species: Human
Sample Types: Cell Culture Supernates

IS Grønningsæ et al. (2020), Targeting Cellular Metabolism in Acute Myeloid Leukemia and The Role of Patient Heterogeneity Cells, 9(5).
PMID: 32392896
Species: Human
Sample Types: Plasma

YC Wei et al. (2020), Cytokine changes during treatment of anti-Caspr2 encephalitis: a case report BMC Neurol, 20(1):299.
PMID: 32791989
Species: Human
Sample Types: Plasma

CB Linander et al. (2020), The effect of circadian-adjusted LED-based lighting on sleep, daytime sleepiness and biomarkers of inflammation in a randomized controlled cross-over trial by pragmatic design in elderly care home dwellers Arch Gerontol Geriatr, 91(0):104223.
PMID: 32805700
Species: Human
Sample Types: Serum

D LaRocca et al. (2019), Comparison of serum and saliva miRNAs for identification and characterization of mTBI in adult mixed martial arts fighters PLoS ONE, 14(1):e0207785.
PMID: 30601825
Species: Human
Sample Types: Cell Culture Supernates

W Kim et al. (2019), Pioglitazone-Primed Mesenchymal Stem Cells Stimulate Cell Proliferation, Collagen Synthesis and Matrix Gene Expression in Tenocytes Int J Mol Sci, 20(3).
PMID: 30678291
Species: Human
Sample Types: Serum

K G?bura et al. (2019), G-CSF administration favours SDF-1 release and activation of neutrophils and monocytes in recipients of autologous peripheral blood progenitor cells Cytokine, 116(0):38-47.
PMID: 30685602
Species: Human
Sample Types: Cell Culture Supernates

W Xu et al. (2019), Mapping of ?/? T cells reveals V?2+ T cells resistance to senescence EBioMedicine, 39(0):44-58.
PMID: 30528453
Species: Human
Sample Types: Plasma

O Olsson et al. (2019), Plasma Profiles of Inflammatory Markers Associated With Active Tuberculosis in Antiretroviral Therapy-Naive Human Immunodeficiency Virus-Positive Individuals Open Forum Infect Dis, 6(2):ofz015.
PMID: 30800697
Species: Human
Sample Types: Tissue Homogenates

S Dhall et al. (2019), Viable cryopreserved umbilical tissue (vCUT) reduces post-operative adhesions in a rabbit abdominal adhesion model Bioact Mater, 4(1):97-106.
PMID: 30723842
Species: Human
Sample Types: Tissue Homogenates

DW Kim et al. (2019), Chronic Rhinosinusitis without Nasal Polyps in Asian Patients Shows Mixed Inflammatory Patterns and Neutrophil-Related Disease Severity Mediators Inflamm., 2019(0):7138643.
PMID: 30766447
Species: Human
Sample Types: Serum

D Kardos et al. (2019), The Composition of Hyperacute Serum and Platelet-Rich Plasma Is Markedly Different despite the Similar Production Method Int J Mol Sci, 20(3).
PMID: 30743992
Species: Human
Sample Types: Cell Culture Supernates

E Chetwin et al. (2019), Antimicrobial and inflammatory properties of South African clinical Lactobacillus isolates and vaginal probiotics Sci Rep, 9(1):1917.
PMID: 30760770
Species: Rabbit
Sample Types: Aqueous Humor

KI Jung et al. (2019), Effects of aqueous suppressants and prostaglandin analogues on early wound healing after glaucoma implant surgery Sci Rep, 9(1):5251.
PMID: 30918313
Species: Human
Sample Types: Cell Culture Supernates

A Ejaz et al. (2019), Adipose-derived stem cell therapy ameliorates ionizing irradiation fibrosis (RIF) via hepatocyte growth factor mediated TGF-? down regulation and recruitment of bone marrow cells Stem Cells, 0(0).
PMID: 30861238
Species: Human
Sample Types: Blood Eluidates

A Leviton et al. (2019), Socioeconomic status and early blood concentrations of inflammation-related and neurotrophic proteins among extremely preterm newborns PLoS ONE, 14(3):e0214154.
PMID: 30913246
Species: Human
Sample Types: Plasma

K Li et al. (2019), Plasm YKL-40 Levels Are Associated with Hypertension in Patients with Obstructive Sleep Apnea Biomed Res Int, 2019(0):5193597.
PMID: 31001555
Species: Human
Sample Types: Cell Lysates

DK Sung et al. (2019), Thrombin Preconditioning of Extracellular Vesicles Derived from Mesenchymal Stem Cells Accelerates Cutaneous Wound Healing by Boosting Their Biogenesis and Enriching Cargo Content J Clin Med, 8(4).
PMID: 31003433
Species: Human
Sample Types: Plasma
Applications: CAR-T Confirmation

Z Ying et al. (2019), A safe and potent anti-CD19 CAR T cell therapy Nat. Med., 0(0).
PMID: 31011207
Species: Human
Sample Types: Serum

NS Utay et al. (2019), Serum Bovine Immunoglobulins Improve Inflammation and Gut Barrier Function in Persons with HIV and Enteropathy on Suppressive ART Pathog Immun, 4(1):124-146.
PMID: 31139758
Species: Human
Sample Types: Serum

KC Cuneo et al. (2019), Serum Levels of Hepatocyte Growth Factor and CD40 Ligand Predict Radiation-Induced Liver Injury Transl Oncol, 12(7):889-894.
PMID: 31078059
Species: Human
Sample Types: Plasma

LF Esemu et al. (2019), Impact of HIV-1 infection on the IGF-1 axis and angiogenic factors in pregnant Cameroonian women receiving antiretroviral therapy PLoS ONE, 14(5):e0215825.
PMID: 31042729
Species: Human
Sample Types: Serum

Schoenfeld J et al. (2019), Pneumonitis resulting from radiation and immune checkpoint blockade illustrates characteristic clinical, radiologic and circulating biomarker features. J Immunother Cancer, 7(1):112.
PMID: 31014385
Species: Human
Sample Types: Plasma

AK Dickey et al. (2019), Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei PLoS Negl Trop Dis, 13(5):e0007354.
PMID: 31067234
Species: Mouse
Sample Types: Plasma

Z Sun et al. (2019), Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice Aging (Albany NY), 0(0).
PMID: 31048563
Species: Human
Sample Types: Plasma

G Geri et al. (2019), Hemodynamic efficiency of hemodialysis treatment with high cut-off membrane during the early period of post-resuscitation shock: The HYPERDIA trial Resuscitation, 0(0).
PMID: 30974188
Species: Human
Sample Types: Plasma

SB Lyne et al. (2019), Biomarkers of cavernous angioma with symptomatic hemorrhage JCI Insight, 4(12).
PMID: 31217347
Species: Human
Sample Types: Urine

O Ashiru et al. (2019), BCG Therapy of Bladder Cancer Stimulates a Prolonged Release of the Chemoattractant CXCL10 (IP10) in Patient Urine Cancers (Basel), 11(7).
PMID: 31277459
Species: Human
Sample Types: Cell Culture Supernates

H Reikvam et al. (2019), High Constitutive Cytokine Release by Primary Human Acute Myeloid Leukemia Cells Is Associated with a Specific Intercellular Communication Phenotype J Clin Med, 8(7).
PMID: 31277464
Species: Human
Sample Types: Serum

L Zaharuddin et al. (2019), A randomized double-blind placebo-controlled trial of probiotics in post-surgical colorectal cancer BMC Gastroenterol, 19(1):131.
PMID: 31340751
Species: Human
Sample Types: Plasma

JL Kruse et al. (2019), Kynurenine metabolism and inflammation-induced depressed mood: A human experimental study Psychoneuroendocrinology, 109(0):104371.
PMID: 31325802
Species: Human
Sample Types: Plasma

RW Browne et al. (2019), High-density lipoprotein cholesterol is associated with multiple sclerosis fatigue: Aï¿½fatigue-metabolism nexus? J Clin Lipidol, 0(0).
PMID: 31307953
Species: Human
Sample Types: Bone Marrow Fluid

T Sun et al. (2019), Multilevel defects in the hematopoietic niche in essential thrombocythemia Haematologica, 0(0).
PMID: 31289202
Species: Human
Sample Types: Serum

BH Lee et al. (2019), Serum Levels of Tumor Necrosis Factor-Î± and Loudness Dependence of Auditory Evoked Potentials at Pretreatment and Posttreatment in Patients with Major Depressive Disorder Brain Sci, 9(10).
PMID: 31561419
Species: Human
Sample Types: Cell Culture Supernates

S Schröder et al. (2019), Effect of Ionizing Radiation on Human EA.hy926 Endothelial Cells under Inflammatory Conditions and Their Interactions with A549 Tumour Cells J Immunol Res, 2019(0):9645481.
PMID: 31565662
Species: Human
Sample Types: Cell Culture Supernates

PJ Thompson et al. (2019), BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes Int J Mol Sci, 20(19).
PMID: 31561444
Species: Human
Sample Types: Plasma

LJ Wang et al. (2019), Peripheral Brain-Derived Neurotrophic Factor and Contactin-1 Levels in Patients with Attention-Deficit/Hyperactivity Disorder J Clin Med, 8(9).
PMID: 31480710
Species: Human
Sample Types: Urine

O Ashiru et al. (2019), BCG Therapy of Bladder Cancer Stimulates a Prolonged Release of the Chemoattractant CXCL10 (IP10) in Patient Urine Cancers (Basel), 11(7).
PMID: 31277459
Species: Human
Sample Types: Cell Culture Supernates

H Reikvam et al. (2019), High Constitutive Cytokine Release by Primary Human Acute Myeloid Leukemia Cells Is Associated with a Specific Intercellular Communication Phenotype J Clin Med, 8(7).
PMID: 31277464
Species: Human
Sample Types: Cell Culture Supernates

M Vetrano et al. (2019), Hyaluronic Acid (HA), Platelet-Rich Plasm and Extracorporeal Shock Wave Therapy (ESWT) promote human chondrocyte regeneration in vitro and ESWT-mediated increase of CD44 expression enhances their susceptibility to HA treatment PLoS ONE, 14(6):e0218740.
PMID: 31251756
Species: Human
Sample Types: Plasma

CL Zimmer et al. (2019), NK cells are activated and primed for skin-homing during acute dengue virus infection in humans Nat Commun, 10(1):3897.
PMID: 31467285
Species: Human
Sample Types: Plasma

P Krashia et al. (2019), Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease Nat Commun, 10(1):3945.
PMID: 31477726
Species: Human
Sample Types: Serum

K Kim et al. (2019), Pre-treatment peripheral biomarkers associated with treatment response in panic symptoms in patients with major depressive disorder and panic disorder: A 12-week follow-up study Compr Psychiatry, 95(0):152140.
PMID: 31669792
Species: Human
Sample Types: Plasma

TEC Kieffer et al. (2019), Lower activation of CD4+ memory T cells in preeclampsia compared to healthy pregnancies persists postpartum J. Reprod. Immunol., 136(0):102613.
PMID: 31585373
Species: Human
Sample Types: Serum

C De Fino et al. (2019), The predictive value of CSF multiple assay in multiple sclerosis: A single center experience Mult Scler Relat Disord, 35(0):176-181.
PMID: 31394405
Species: Human
Sample Types: Urine

A Li et al. (2019), Urinary NGAL and RBP Are Biomarkers of Normoalbuminuric Renal Insufficiency in Type 2 Diabetes Mellitus J Immunol Res, 2019(0):5063089.
PMID: 31637265
Species: Human
Sample Types: Cell Culture Supernates

AI Marusina et al. (2019), Tunable hydrogels for mesenchymal stem cell delivery: integrin-induced transcriptome alterations and hydrogel optimization for human wound healing Stem Cells, 0(0).
PMID: 31648388
Species: Human
Sample Types: Cell Culture Supernates

RM Rodriguez et al. (2019), Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes Cell Rep, 29(4):860-872.e5.
PMID: 31644909
Species: Human
Sample Types: Plasma

RE Elphinston et al. (2019), Early malaria infection, dysregulation of angiogenesis, metabolism and inflammation across pregnancy, and risk of preterm birth in Malawi: A cohort study PLoS Med., 16(10):e1002914.
PMID: 31574087
Species: Human
Sample Types: Wound Fluid

JP Hodde et al. (2019), Characterization of the local wound environment following treatment of chronic leg ulcers with SIS wound matrix J Tissue Viability, 0(0).
PMID: 31866230
Species: Human
Sample Types: Aqueous Humor

B Lu et al. (2019), Multiple cytokine analyses of aqueous humor from the patients with retinitis pigmentosa Cytokine, 127(0):154943.
PMID: 31810025
Species: Human
Sample Types: Serum

S Brandt et al. (2019), Altered monocytic phenotypes are linked with systemic inflammation and may be linked to mortality in dialysis patients Sci Rep, 9(1):19103.
PMID: 31836803
Species: Human
Sample Types: Plasma

NP Kumar et al. (2019), Plasma chemokines are biomarkers of disease severity, higher bacterial burden and delayed sputum culture conversion in pulmonary tuberculosis Sci Rep, 9(1):18217.
PMID: 31796883
Species: Human
Sample Types: Plasma

A Shieh et al. (2019), Gut permeability, inflammation, and bone density across the menopause transition JCI Insight, 0(0).
PMID: 31830000
Species: Human
Sample Types: Saliva

W Xiao et al. (2019), Endotype-driven prediction of acute exacerbations in chronic obstructive pulmonary disease (EndAECOPD): protocol for a prospective cohort study BMJ Open, 9(11):e034592.
PMID: 31690612
Species: Human
Sample Types: Plasma

M Selvaraja et al. (2019), Elevated interleukin-25 and its association to Th2 cytokines in systemic lupus erythematosus with lupus nephritis PLoS ONE, 14(11):e0224707.
PMID: 31697750
Species: Human
Sample Types: Plasma

EA Barbu et al. (2019), Pro-inflammatory cytokines associate with NETosis during sickle cell vaso-occlusive crises Cytokine, 127(0):154933.
PMID: 31778959
Species: Human
Sample Types: Synovial Fluid

CM Arnholt et al. (2019), Postmortem Retrieval Analysis of Metallosis and Periprosthetic Tissue Metal Concentrations in Total Knee Arthroplasty J Arthroplasty, 0(0).
PMID: 31699531
Species: Human
Sample Types: Serum

J Weiner et al. (2019), Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium Sci Rep, 9(1):20362.
PMID: 31889148
Species: Human
Sample Types: Cell Lysates

M Haddad et al. (2019), Methylglyoxal and Glyoxal as Potential Peripheral Markers for MCI Diagnosis and Their Effects on the Expression of Neurotrophic, Inflammatory and Neurodegenerative Factors in Neurons and in Neuronal Derived-Extracellular Vesicles Int J Mol Sci, 20(19).
PMID: 31623327
Species: Human
Sample Types: Whole Blood

S Harm et al. (2019), Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application Int J Mol Sci, 20(21).
PMID: 31683553
Species: Human
Sample Types: Tissue Homogenates

A Schulz et al. (2019), Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization Cell Rep, 29(5):1074-1081.e5.
PMID: 31665625
Species: Human
Sample Types: Plasma

V Frodermann et al. (2019), Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells Nat. Med., 25(11):1761-1771.
PMID: 31700184
Species: Human
Sample Types: CSF

CM Manyelo et al. (2019), Application of Cerebrospinal Fluid Host Protein Biosignatures in the Diagnosis of Tuberculous Meningitis in Children from a High Burden Setting Mediators Inflamm., 2019(0):7582948.
PMID: 31148946
Species: Human
Sample Types: Serum

X Yin et al. (2019), Alteration of the IL-33-sST2 pathway in hypertensive patients and a mouse model Hypertens. Res., 0(0).
PMID: 31235844
Species: Human
Sample Types: Serum

L Wu et al. (2019), Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans Cell Death Dis, 10(6):468.
PMID: 31197160
Species: Human
Sample Types: Plasma

T Sun et al. (2019), TAZ is required for lung alveolar epithelial cell differentiation after injury JCI Insight, 5(0).
PMID: 31211697
Species: Human
Sample Types: Plasma

V Vítková et al. (2018), Endothelial Microvesicles and Soluble Markers of Endothelial Injury in Critically Ill Newborns Mediators Inflamm., 2018(0):1975056.
PMID: 30116143
Species: Human
Sample Types: Aqueous Humor

Z Zhang et al. (2018), Matricellular Protein Levels in Aqueous Humor and Surgical Outcomes of Trabeculectomy Invest. Ophthalmol. Vis. Sci., 59(10):3906-3910.
PMID: 30073351
Species: Human
Sample Types: Cell Lysates

Y Han et al. (2018), Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis Redox Biol, 16(0):32-46.
PMID: 29475133
Species: Human
Sample Types: Plasma

D Silva et al. (2018), Meal-exercise challenge and physical activity reduction impact on immunity and inflammation (MERIIT trial) Contemp Clin Trials Commun, 10(0):177-189.
PMID: 30009276
Species: Human
Sample Types: Cell Culture Supernates

PM Grin et al. (2018), Low-density lipoprotein (LDL)-dependent uptake of Gram-positive lipoteichoic acid and Gram-negative lipopolysaccharide occurs through LDL receptor Sci Rep, 8(1):10496.
PMID: 30002483
Species: Human
Sample Types: Aqueous Humor

EL Ashworth B et al. (2018), Uteroglobin and FLRG concentrations in aqueous humor are associated with age in primary open angle glaucoma patients BMC Ophthalmol, 18(1):57.
PMID: 29482497
Species: Human
Sample Types: Cell Culture Supernates

CP Miller et al. (2018), A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis Neoplasia, 20(6):610-620.
PMID: 29747161
Species: Human
Sample Types: Cell Culture Supernates

D Zhao et al. (2018), Hypoxia with Wharton's jelly mesenchymal stem cell coculture maintains stemness of umbilical cord blood-derived CD34+ cells Stem Cell Res Ther, 9(1):158.
PMID: 29895317
Species: Human
Sample Types: Serum

I Lochman et al. (2018), Serum Cytokine and Growth Factor Levels in Children with Autism Spectrum Disorder Med. Sci. Monit., 24(0):2639-2646.
PMID: 29705814
Species: Human
Sample Types: BALF

L Levy et al. (2018), Sequential broncho-alveolar lavages reflect distinct pulmonary compartments: clinical and research implications in lung transplantation Respir. Res., 19(1):102.
PMID: 29801490
Species: Human
Sample Types: Serum

AR Cho et al. (2018), Effects of 4-Week Intervention with Ulmus macrocarpa Hance Extract on Immune Function Biomarkers in Healthy Adults: A Randomized Controlled Trial Evid Based Complement Alternat Med, 2018(0):5690816.
PMID: 29681977
Species: Human
Sample Types: Plasma

M Abu-Farha et al. (2018), Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension Lipids Health Dis, 17(1):35.
PMID: 29490644
Species: Human
Sample Types: Serum

SMC Spoorenber et al. (2018), Course of SP-D, YKL-40, CCL18 and CA 15-3 in adult patients hospitalised with community-acquired pneumonia and their association with disease severity and aetiology: A post-hoc analysis PLoS ONE, 13(1):e0190575.
PMID: 29324810
Species: Human
Sample Types: Cell Culture Supernates

DG Leuning et al. (2018), The cytokine secretion profile of mesenchymal stromal cells is determined by surface structure of the microenvironment Sci Rep, 8(1):7716.
PMID: 29769543
Species: Human
Sample Types: Plasma

HQ Cai et al. (2018), Increased macrophages andï¿½changed brain endothelial cell gene expression in the frontal cortex of people with schizophrenia displaying inflammation Mol. Psychiatry, 0(0).
PMID: 30214039
Species: Human
Sample Types: Serum

E Kalanxhi et al. (2018), Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer Br. J. Cancer, 118(10):1322-1328.
PMID: 29695770
Species: Human
Sample Types: Cell Culture Supernates

AM Bates et al. (2018), Matrix Metalloproteinase Response of Dendritic Cell, Gingival Epithelial Keratinocyte, and T-Cell Transwell Co-Cultures Treated with Porphyromonas gingivalis Hemagglutinin-B Int J Mol Sci, 19(12).
PMID: 30544510
YS Byun et al. (2018), Marked infiltration of neutrophils at the upper palpebral conjunctiva in patients with chronic graft-versus-host disease Ocul Surf, 0(0).
PMID: 30578957
Species: Human
Sample Types: Cell Culture Supernates

S Perriot et al. (2018), Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines Stem Cell Reports, 11(5):1199-1210.
PMID: 30409508
Species: Human
Sample Types: Cell Culture Supernates

L Wampach et al. (2018), Birth mode is associated with earliest strain-conferred gut microbiome functions and immunostimulatory potential Nat Commun, 9(1):5091.
PMID: 30504906
Species: Human
Sample Types: Cell Lysates

W Klinngam et al. (2018), Cathepsin S Alters the Expression of Pro-Inflammatory Cytokines and MMP-9, Partially through Protease-Activated Receptor-2, in Human Corneal Epithelial Cells Int J Mol Sci, 19(11).
PMID: 30423938
Species: Human
Sample Types: Cell Culture Supernates

S Kim et al. (2018), Exosomes Secreted from Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Accelerate Skin Cell Proliferation Int J Mol Sci, 19(10).
PMID: 30314356
Species: Human
Sample Types: Cell Culture Supernates

S Muntaka et al. (2018), IFN-? and IL-17A differentially influence the response of human macrophages and neutrophils to Pseudomonas aeruginosa infection Infect. Immun., 0(0).
PMID: 30455194
Species: Human
Sample Types: Cell Culture Supernates

PJ Huang et al. (2018), Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses J. Biol. Chem., 0(0).
PMID: 30377253
Species: Human
Sample Types: Cell Culture Supernates

B Kan et al. (2018), Cellular metabolism constrains innate immune responses in early human ontogeny Nat Commun, 9(1):4822.
PMID: 30446641
Species: Human
Sample Types: Plasma

MA Wiewel et al. (2018), The host response in critically ill sepsis patients on statin therapy: a prospective observational study Ann Intensive Care, 8(1):9.
PMID: 29349709
Species: Human
Sample Types: Plasma

X Wang et al. (2018), Macrophage Migration Inhibitory Factor and microRNA-451a in Response to Mindfulness-Based Therapy or Treatment as usual in Patients with Depression, Anxiety or Stress- and Adjustment Disorders Int. J. Neuropsychopharmacol., 0(0).
PMID: 29373661
Species: Human
Sample Types: Cell Culture Supernates

Chang Y et al. (2018), A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells. Mucosal Immunol, 12(2):457-467.
PMID: 29695840
Species: Human
Sample Types: Serum

Wu X et al. (2018), Anti-CTLA-4 based therapy elicits humoral immunity to galectin-3 in patients with metastatic melanoma. Oncoimmunology, 7(7):e1440930.
PMID: 29900046
Species: Human
Sample Types: Serum

P Jain et al. (2018), A multivariate approach to investigate the combined biological effects of multiple exposures J Epidemiol Community Health, 0(0).
PMID: 29563153
Species: Human
Sample Types: Cell Culture Supernates

A Forestier et al. (2018), Altered B lymphocyte homeostasis and functions in systemic sclerosis Autoimmun Rev, 0(0).
PMID: 29343447
Species: Human
Sample Types: Serum

A Gaye et al. (2018), Whole-genome transcriptomic insights into protective molecular mechanisms in metabolically healthy obese African Americans NPJ Genom Med, 3(0):4.
PMID: 29387454
Species: Human
Sample Types: Cell Culture Supernates

U Tsutsumi-K et al. (2018), Decreased MCP-1/CCR2 axis-mediated chemotactic effect of conjunctival fibroblasts after transdifferentiation into myofibroblasts Exp. Eye Res., 170(0):76-80.
PMID: 29458061
Species: Human
Sample Types: Nasal Fluid

RS Thwaites et al. (2018), Biphasic activation of complement and fibrinolysis during the human nasal allergic response J. Allergy Clin. Immunol., 0(0).
PMID: 29427640
Species: Human
Sample Types: Serum

L Yan et al. (2018), Serum YKL-40 as a biomarker for liver fibrosis in chronic hepatitis B patients with normal and mildly elevated ALT Infection, 0(0).
PMID: 29600444
Species: Human
Sample Types: Cell Culture Supernates

DG Leuning et al. (2017), Clinical-Grade Isolated Human Kidney Perivascular Stromal Cells as an Organotypic Cell Source for Kidney Regenerative Medicine Stem Cells Transl Med, 6(2):405-418.
PMID: 28191776
Species: Human
Sample Types: Cell Culture Supernates

S Giakoumelo et al. (2017), Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release Sci Rep, 7(1):2001.
PMID: 28515460
Species: Human
Sample Types: Cell Culture Supernates

IY Mattisson et al. (2017), Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease EBioMedicine, 26(0):187-197.
PMID: 29208468
Species: Human
Sample Types: Cell Culture Supernates

T Hueso et al. (2017), Citrulline and Monocyte-Derived Macrophage Reactivity Prior to Conditioning Predict Acute Graft-Verus-Host Disease Biol. Blood Marrow Transplant, 0(0).
PMID: 28263922
Species: Human
Sample Types: Cell Culture Supernates

AL Jung et al. (2017), Legionella pneumophila infection activates bystander cells differentially by bacterial and host cell vesicles Sci Rep, 7(1):6301.
PMID: 28740179
Species: Human
Sample Types: Plasma

SH Lee et al. (2017), Clinical implications of the plasma EphA2 receptor level in critically ill patients with septic shock Sci Rep, 7(1):17612.
PMID: 29242524
Species: Human
Sample Types: Serum

D Liu et al. (2017), Immune adaptation to chronic intense exercise training: new microarray evidence BMC Genomics, 18(1):29.
PMID: 28056786
Species: Human
Sample Types: Cell Culture Supernates

I Lampronti et al. (2017), ?-Sitosterol Reduces the Expression of Chemotactic Cytokine Genes in Cystic Fibrosis Bronchial Epithelial Cells Front Pharmacol, 8(0):236.
PMID: 28553226
Species: Human
Sample Types: Cell Culture Supernates

A Futakuchi et al. (2017), Molecular Mechanisms Underlying the Filtration Bleb-Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA) Invest. Ophthalmol. Vis. Sci., 58(4):2421-2429.
PMID: 28448670
Species: Human
Sample Types: Cell Culture Supernates

C Boudousqui et al. (2017), Polyfunctional response by ImmTAC (IMCgp100) redirected CD8(+) and CD4(+) T cells Immunology, 0(0).
PMID: 28640942
Species: Human
Sample Types: Complex Sample Type

A Leviton et al. (2017), Antecedents and correlates of blood concentrations of neurotrophic growth factors in very preterm newborns Cytokine, 0(0).
PMID: 28396037
Species: Human
Sample Types: Plasma

A Gohar et al. (2017), Circulating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis Int. J. Cardiol., 0(0).
PMID: 28389123
Species: Human
Sample Types: Cell Culture Supernates

ME Vogel et al. (2017), Bilirubin Prevents Atherosclerotic Lesion Formation in Low-Density Lipoprotein Receptor-Deficient Mice by Inhibiting Endothelial VCAM-1 and ICAM-1 Signaling J Am Heart Assoc, 6(4).
PMID: 28365565
Species: Human
Sample Types: Serum

J Vlaanderen et al. (2017), Acute changes in serum immune markers due to swimming in a chlorinated pool Environ Int, 105(0):1-11.
PMID: 28478232
Species: Human
Sample Types: Plasma

S Seang et al. (2017), Circulating LOXL2 Levels Reflect Severity of Intestinal Fibrosis and GALT CD4(+) T Lymphocyte Depletion in Treated HIV Infection Pathog Immun, 2(2):239-252.
PMID: 28782046
Species: Human
Sample Types: Plasma

E Shabani et al. (2017), Elevated cerebrospinal fluid tumor necrosis factor is associated with acute and long-term neurocognitive impairment in cerebral malaria Parasite Immunol., 0(0).
PMID: 28453871
Species: Human
Sample Types: Plasma

JJ De Haan et al. (2017), Growth Differentiation Factor 15 Is Associated With Major Amputation and Mortality in Patients With Peripheral Artery Disease J Am Heart Assoc, 6(9).
PMID: 28855167
Species: Human
Sample Types: Cell Culture Supernates

O Dayoub et al. (2017), Estrogen receptor ?/HDAC/NFAT axis for delphinidin effects on proliferation and differentiation of T lymphocytes from patients with cardiovascular risks Sci Rep, 7(1):9378.
PMID: 28839227
Species: Human
Sample Types: Plasma

YK Yong et al. (2017), Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease J Transl Med, 15(1):121.
PMID: 28569153
Species: Human
Sample Types: Cell Culture Supernates

YL Hsu et al. (2017), Hypoxic Lung-Cancer-Derived Extracellular Vesicle MicroRNA-103a Increases the Oncogenic Effects of Macrophages by Targeting PTEN Mol. Ther., 0(0).
PMID: 29292163
Species: Human
Sample Types: Cell Culture Supernates

MT Sutton et al. (2017), Mesenchymal Stem Cell Soluble Mediators and Cystic Fibrosis J Stem Cell Res Ther, 7(9).
PMID: 29291140
Species: Human
Sample Types: Nasal Lavage Fluid

M Talikka et al. (2017), Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal Epithelium Clin Med Insights Circ Respir Pulm Med, 11(0):1179548417710.
PMID: 28620266
Species: Human
Sample Types: BALF

AM Manicone et al. (2017), Matrix Metalloproteinase-28 Is a Key Contributor to Emphysema Pathogenesis Am. J. Pathol., 0(0).
PMID: 28399390
Species: Human
Sample Types: Serum

Y Cui et al. (2017), Aberrant SYK kinase signaling is essential for tumorigenesis induced by TSC2 inactivation Cancer Res, 0(0).
PMID: 28202529
Species: Human
Sample Types: Cell Culture Supernates

LK Winberg et al. (2017), Microparticles from patients with systemic lupus erythematosus induce production of reactive oxygen species and degranulation of polymorphonuclear leukocytes Arthritis Res. Ther., 19(1):230.
PMID: 29041967
Species: Human
Sample Types: Serum

Y van Sleen et al. (2017), Involvement of Monocyte Subsets in the Immunopathology of Giant Cell Arteritis Sci Rep, 7(1):6553.
PMID: 28747747
Species: Human
Sample Types: Cell Culture Supernates

ME Seamone et al. (2017), VEGF-A is increased in exogenous endophthalmitis Can. J. Ophthalmol., 52(3):277-282.
PMID: 28576209
Species: Human
Sample Types: Plasma

RV Luthold et al. (2017), Gut microbiota interactions with the immunomodulatory role of vitamin D in normal individuals Metab. Clin. Exp., 69(0):76-86.
PMID: 28285654
Species: Human
Sample Types: Tissue Culture Supernates

TL Rimington et al. (2017), Defining the inflammatory signature of human lung explant tissue in the presence and absence of glucocorticoid F1000Res, 6(0):460.
PMID: 28721202
Species: Human
Sample Types: Plasma

RM Koch et al. (2017), Development of Endotoxin Tolerance Does Not Influence the Response to a Challenge with the Mucosal Live-Attenuated Influenza Vaccine in Humans In Vivo Front Immunol, 8(0):1600.
PMID: 29312282
Species: Human
Sample Types: Cell Culture Supernates

(2016), T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions PLoS ONE, 11(7):e0160291.
PMID: 27467144
Species: Human
Sample Types: CSF

KA Thibert et al. (2016), Cerebral Spinal Fluid levels of Cytokines are elevated in Patients with Metachromatic Leukodystrophy Sci Rep, 6(0):24579.
PMID: 27079147
Species: Human
Sample Types: Plasma

(2016), Assessment of the Role of Metabolic Determinants on the Relationship between Insulin Sensitivity and Secretion PLoS ONE, 11(12):e0168352.
PMID: 28002466
Species: Human
Sample Types: Plasma

James Bussel (2016), Effect of thrombopoietin-receptor agonists on circulating cytokine and chemokine levels in patients with primary immune thrombocytopenia (ITP) Platelets, 0(0):1-6.
PMID: 27819522
Species: Human
Sample Types: Cell Culture Supernates

Daniel Hsu (2016), CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention Infect Immun, 0(0).
PMID: 27271746
Species: Human
Sample Types: Serum

(2016), Data on serologic inflammatory biomarkers assessed using multiplex assays and host characteristics in the Multicenter AIDS Cohort Study (MACS) Data Brief, 9(0):262-70.
PMID: 27668272
Species: Human
Sample Types: Serum

Richard J Nowak (2016), Durability of the Rituximab Response in Acetylcholine Receptor Autoantibody-Positive Myasthenia Gravis JAMA Neurol, 0(0).
PMID: 27893014
Species: Human
Sample Types: Cell Culture Supernates

Robert J Thomas (2016), Immobilized hematopoietic growth factors onto magnetic particles offer a scalable strategy for cell therapy manufacturing in suspension cultures Biotechnol J, 0(0).
PMID: 27863041
Species: Human
Sample Types: Cell Culture Supernates

L Hasib et al. (2016), Functional and homeostatic defects of regulatory T cells in patients with coronary artery disease J. Intern. Med, 279(1):63-77.
PMID: 26260103
Species: Human
Sample Types: Serum

Kuan-Ting Liu (2016), Serum Galectin-9 and Galectin-3-Binding Protein in Acute Dengue Virus Infection Int J Mol Sci, 17(6).
PMID: 27240351
Species: Human
Sample Types: Plasma

(2016), In vivo imaging of eribulin-induced reoxygenation in advanced breast cancer patients: a comparison to bevacizumab Br J Cancer, 114(11):1212-8.
PMID: 27140309
Species: Human
Sample Types: Plasma

(2016), Impact of placental Plasmodium falciparum malaria infection on the Cameroonian maternal and neonate's plasma levels of some cytokines known to regulate T cells differentiation and function Malar. J., 15(1):561.
PMID: 27871325
Species: Human
Sample Types: Amniotic Fluid

(2016), Levels of Adipokines in Amniotic Fluid and Cord Blood Collected from Dichorionic-Diamniotic Twins Discordant for Fetal Growth PLoS ONE, 11(5):e0154537.
PMID: 27135745
Species: Human
Sample Types: Plasma

(2016), Increased levels of 3-hydroxykynurenine parallel disease severity in human acute pancreatitis Sci Rep, 6(0):33951.
PMID: 27669975
Species: Human
Sample Types: Serum

Onán Pérez-Hern (2016), Malondialdehyde as a Prognostic Factor in Alcoholic Hepatitis Alcohol Alcohol, 0(0).
PMID: 28007738
Species: Human
Sample Types: Plasma

David R Goldsmith (2016), Inflammatory markers are associated with decreased psychomotor speed in patients with major depressive disorder Brain Behav. Immun, 56(0):281-8.
PMID: 27040122
Species: Human
Sample Types: Cell Culture Supernates

Fleming B et al. (2015), The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. J Leukoc Biol, 98(3):395-407.
PMID: 26048978
Species: Human
Sample Types: Cell Culture Supernates

Karkeni E et al. (2015), Vitamin D limits chemokine expression in adipocytes and macrophage migration in vitro and in male mice. Endocrinology, 156(5):1782-93.
PMID: 25730105
Species: Human
Sample Types: Serum

Butterfield L et al. (2014), Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients. J Transl Med, 12(0):86.
PMID: 24708667
Species: Human
Sample Types: Serum

Wu X et al. (0), Angiopoietin-2 as a Biomarker and Target for Immune Checkpoint Therapy. Cancer Immunol Re5(1):17-28.
PMID: 28003187
Species: Human
Sample Types: Serum

Carlyn C et al. (0), Analysis of septic biomarker patterns: prognostic value in predicting septic state. Diagn Microbiol Infect Di83(3):312-8.
PMID: 26272282
Species: Human
Sample Types: Plasma

Nilholm C et al. (0), Dietary intervention with an Okinawan-based Nordic diet in type 2 diabetes renders decreased interleukin-18 concentrations and increased neurofilament light concentrations in plasma. Nutr Re60(0):13-25.
PMID: 30527256
Species: Human
Sample Types: Platelet Poor Plasma

Smadja D et al. (0), Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients. Angiogenesi0(0).
PMID: 32458111

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Customer Reviews for Human Luminex® Discovery Assay (36)

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36 customer ratings

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Human Luminex Discovery Assay

Name: Anonymous

Sample Tested: A549 human lung carcinoma cell line,Peripheral blood monocytes

Verified Customer | Posted 04/26/2022
Human Luminex Discovery Assay

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 11/19/2021
Human Luminex Discovery Assay

Name: Anonymous

Sample Tested: Cell Culture Media

Verified Customer | Posted 08/13/2021
Human Luminex Discovery Assay

Name: Anonymous

Sample Tested: Human CD 8 T cell media supernatant

Verified Customer | Posted 08/05/2021
Human Luminex Discovery Assay

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 07/20/2021
Human Luminex Discovery Assay

Name: Anonymous

Sample Tested: EDTA Plasma

Verified Customer | Posted 06/29/2021

Easy to use 25 plex, significantly easier over ELISAS. 24/25 analytes r^2>0.999 on standard curve, and slightly improved IGFBP3 accuracy over previous kits (with r^2 = 0.987).
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Sputum sol

Verified Customer | Posted 02/09/2021
Human Magnetic Luminex Assay

Name: David Zablotny

Sample Tested: EDTA Plasma

Verified Customer | Posted 11/17/2020
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Serum

Verified Customer | Posted 10/04/2020
Human Magnetic Luminex Assay

Name: Zhenping Wang

Sample Tested: Cell Culture Supernates

Verified Customer | Posted 10/01/2020
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Peripheral blood mononuclear cells (PBMCs)

Verified Customer | Posted 06/05/2020
Human Magnetic Luminex Assay

Name: Derek Poore

Sample Tested: A375 cell supernatants

Verified Customer | Posted 04/27/2020

First time I ever used the Magnetic Luminex Assay and I had no trouble running the assay.
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 04/21/2020

a target protein expressing cancer cells co-incubate with PBMC
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 04/21/2020

cancer cell co-incubate with healthy donor PBMC with lead candidate mAbs.
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Plasma

Verified Customer | Posted 02/25/2020
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: in vitro cell culture

Verified Customer | Posted 10/19/2019
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: in vitro cell culture

Verified Customer | Posted 08/13/2019
Name: Anonymous

Sample Tested: Serum

Verified Customer | Posted 06/19/2019
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Saliva

Verified Customer | Posted 04/02/2019
Human Magnetic Luminex Assay

Name: Ben Minden-Birkenmaier

Sample Tested: HL-60 human acute promyelocytic leukemia cell line

Verified Customer | Posted 01/30/2019

Gave us clear readouts of the level of RANTES in our samples
Human Magnetic Luminex Assay

Name: William King

Sample Tested: Electrospun Templates,Manuka Honey,Neutrophils

Verified Customer | Posted 01/17/2019
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 01/16/2019
Name: Anonymous

Sample Tested: mouse serum and recombinant TNF alpha

Verified Customer | Posted 01/07/2019

the standard was great but the test did not detect TNF alpha in our material while other ELISAs did
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: EDTA Plasma

Verified Customer | Posted 07/13/2018
Human Magnetic Luminex Assay

Name: Luiz Alexandre

Sample Tested: EDTA Plasma

Verified Customer | Posted 07/13/2018
Name: Anonymous

Sample Tested: Heparin Plasma

Verified Customer | Posted 05/28/2018
Name: Anonymous

Sample Tested: Plasma

Verified Customer | Posted 05/28/2018

We found that the volumes for beads, antibodies, and streptavidin biotin were higher than in previous kits. Even a couple of mls more made easier to prepare the suspension with enough volume to run a whole plate. Bubbles usually make the experiment more complicated but this time we did not find that the buffers were too foamy.
Human Magnetic Luminex Assay

Name: satyendra tripathi

Sample Tested: Heparin Plasma

Verified Customer | Posted 05/13/2018
Human Magnetic Luminex Assay

Name: Leslie Priddy

Sample Tested: Serum

Verified Customer | Posted 04/03/2018
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Human tissue

Verified Customer | Posted 12/15/2017
Human Magnetic Luminex Assay

Name: Luping Chen

Sample Tested: LXSAHM

Verified Customer | Posted 11/13/2017
Name: Adriana Trajtman

Sample Tested: induced sputum

Verified Customer | Posted 10/27/2017

This was the first time we ran induced sputums to test these biomarkers. The values obtained were low or negative. We used the samples without dilution as we had no literature data to refer to.
Name: Adriana Trajtman

Sample Tested: Heparin Plasma

Verified Customer | Posted 10/27/2017
Name: Adriana Trajtman

Sample Tested: Heparin Plasma,induced sputum

Verified Customer | Posted 10/27/2017
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Tissue Culture Media

Verified Customer | Posted 06/14/2016
Human Magnetic Luminex Assay

Name: Anonymous

Sample Tested: Tissue Culture Media

Verified Customer | Posted 06/13/2016

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Showing 1 - 5 of 36 reviews Showing All

FAQs for Human Luminex® Discovery Assay

What is the reason for the recommendation to use 35 µL sample volume, instead of the default 50 µL volume, for Luminex multiplex containing > 25 analytes, when assayed on Luminex MAGPIX® analyzer?

R&D Systems recommend 35 µL sample volume for > 25 analytes to control the number of beads in the sample load when using Luminex MAGPIX® analyzer. Luminex MAGPIX® analyzer is a non-flow-based reader which utilizes a magnet to hold the magnetic microparticles in a monolayer in a chamber where the beads are imaged and then processed by the software to generate data. Since MAGPIX® system pushes the entire Sample Load Volume into the chamber, multiplex assay containing > 25 analytes may overload the chamber capacity with 50 µL sample load default setting. The captured images can have too many beads in them to give accurate results, and some of the analytes/regions may present lower than desired bead counts.
Does the Luminex Human Magnetic Assay detect soluble form or membrane-bound analyte?

The sample types typically validated by R&D Systems for Luminex assays contain soluble form of proteins, and therefore it is expected that the soluble form of proteins are detected. It is possible there are assays that alo detect the membrane form of respective target proteins, however, R&D Systems does not generally evaluate our assays against samples known to contain membrane-bound proteins.
What speed do you recommend centrifuging cell culture supernates samples?

For cell culture supernates, remove particulates by centrifuging for 5 minutes at 500 x g.

Human Luminex® Discovery Assay

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Human Luminex Discovery Assay

Human Luminex Discovery Assay

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Human Magnetic Luminex Assay

Human Magnetic Luminex Assay

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Human Magnetic Luminex Assay

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Human Magnetic Luminex Assay

Human Magnetic Luminex Assay

Human Magnetic Luminex Assay

Human Magnetic Luminex Assay

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Human Magnetic Luminex Assay

Human Magnetic Luminex Assay

Human Magnetic Luminex Assay

Human Magnetic Luminex Assay

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Human Magnetic Luminex Assay

Human Magnetic Luminex Assay

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