21 results for "GTPase Inhibitors" in Products
GTPase Inhibitors Products
Selective inhibitor of Rac1-GEF interaction; antioncogenic
| Chemical Name: | N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride |
| Purity: | ≥98% (HPLC) |
Non-competitive dynamin inhibitor
| Chemical Name: | 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide |
| Purity: | ≥98% (HPLC) |
Rho inhibitor
| Chemical Name: | D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent Rac family inhibitor
| Chemical Name: | 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride |
| Purity: | ≥98% (HPLC) |
Gα-protein inhibitor; potent inhibitor of Gq/11 signaling
| Chemical Name: | (R)-1-((3S,6S,9S,12S,18R,21S,22R)-21-acetamido-18-benzyl-3-((R)-1-methoxyethyl)-4,9,10,12,16,22-hexamethyl-15-methylene-2,5,8,11,14,17,20-heptaoxo-1,19-dioxa-4,7,10,13,16-pentaazacyclodocosan-6-yl)-2-methylpropyl (2S,3R)-2-acetamido-3-hydroxy-4-methylpentanoate |
| Purity: | ≥95% (HPLC) |
Potent farnesyl diphosphate (FPP) synthase inhibitor
| Alternate Names: | Zometa |
| Chemical Name: | [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid |
| Purity: | ≥98% (HPLC) |
Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis
| Chemical Name: | 3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone |
| Purity: | ≥98% (HPLC) |
Dynamin inhibitor; analog of dynasore (Cat. No. 2897)
| Alternate Names: | Dyngo 4a |
| Chemical Name: | 3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide |
| Purity: | ≥98% (HPLC) |
Selective Cdc42 Rho family inhibitor
| Alternate Names: | CID 2950007 |
| Chemical Name: | 4-[4,5-Dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Epac inhibitor
| Chemical Name: | α-[(2-(3-Chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-3-isoxazolepropanenitrile |
| Purity: | ≥98% (HPLC) |
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
| Chemical Name: | [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone |
| Purity: | ≥98% (HPLC) |
Dynamin I inhibitor
| Chemical Name: | 2-Cyano-3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-N-octyl-2-propenamide |
| Purity: | ≥98% (HPLC) |
Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable
| Purity: | ≥95% (HPLC) |
High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ
| Chemical Name: | 2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole trihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective ARF6 inhibitor
| Chemical Name: | 3-(4-Chlorophenyl)-5-(4-nitrophenyl)-2-(phenylmethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one |
| Purity: | ≥98% (HPLC) |
DOCK2-Rac1 interaction inhibitor
| Chemical Name: | 4-[3-(2-Chlorophenyl)-2-propen-1-ylidene]-1-phenyl-3,5-pyrazolidinedione |
| Purity: | ≥98% (HPLC) |
Rac inhibitor
| Chemical Name: | N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% (HPLC) |
Geranylgeranyltransferase-I (GGTase-I) inhibitor
| Chemical Name: | (2R)-3,3,3-Trifluoro-2-methoxy-1-[(7R)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-1-propanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Epac2 inhibitor
| Chemical Name: | 1,3,5-Trimethyl-2-[(4-methylphenyl)sulfonyl]benzene |
| Purity: | ≥98% (HPLC) |
Selective Epac2 inhibitor
| Chemical Name: | 2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole |
| Purity: | ≥98% (HPLC) |
Potent covalent inhibitor of the RAS domain of the PI3K/p110α interaction
| Chemical Name: | 5-((1R,2S,5S)-2-(2-Chloro-3-fluorophenyl)-3-azabicyclo[3.1.0]hexan-3-yl)-N-((R,E)-4-(methylsulfonyl)but-3-en-2-yl)pyrazine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
