HJC 0350
Tocris Bioscience, part of Bio-Techne | Catalog # 4844
Selective Epac2 inhibitor
Product Description
HJC 0350 is a selective Epac2 inhibitor (IC50 = 0.3 μM). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.Product Specifications
Molecular Weight
277.38
Formula
C15H19NO2S
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole
CAS Number
885434-70-8
PubChem ID
22200891
InChI Key
AFZWZVLPIMHLSE-UHFFFAOYSA-N
SMILES
CC1=CC(C)=C(S(N2C(C)=CC(C)=C2)(=O)=O)C(C)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 13.87 | 50 | |
| Ethanol | 5.55 | 20 |
Preparing Stock Solutions
for HJC 0350
The following data is based on the product molecular weight 277.38
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 7.21 mL | 36.05 mL | 72.10 mL |
| 2.5 mM | 1.44 mL | 7.21 mL | 14.42 mL |
| 5 mM | 0.72 mL | 3.61 mL | 7.21 mL |
| 25 mM | 0.14 mL | 0.72 mL | 1.44 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Chen Identification and characterization of small molecules as potent and specific EPAC2 antagonists. J.Med.Chem. 2013 PMID: 23286832
Product Specific Notices for HJC 0350
For research use only
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