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107 results for "S1P1/EDG-1" in Products

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S1P1/EDG-1 Products

EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P family regulates essential cellular processes such as proliferation, migration, cytoskeletal organization, and differentiation.

Human S1P1/EDG-1 Antibody (218713)
Catalog #: MAB2016
(1)
Citations (14)
Product Documents
Images (2)

Clone 218713 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #218713
Applications:
Flow, CyTOF-ready
Detection of S1P1/EDG-1 antibody in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
(2)
Catalog #
Availability
Size / Price
Qty
MAB2016-100
MAB2016-500
MAB2016-SP
Bulk Order

Mouse S1P1/EDG-1 Antibody (713412)
Catalog #: MAB7089
Citations (46)
Product Documents
Images (4)
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
IHC, Flow, CyTOF-ready
Detection of S1P1/EDG-1 antibody in HEK293 Human Cell Line Transfected With S1P1/EDG-1 antibody by Flow Cytometry.
(4)
Catalog #
Availability
Size / Price
Qty
MAB7089
MAB7089-SP
Bulk Order

S1P1/EDG-1 Antibody
Catalog #: NB120-11424
Citations (6)
Product Documents
Images (8)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF, IP
Western Blot: S1P1/EDG-1 Antibody [NB120-11424]
(8)
Catalog #
Availability
Size / Price
Qty
NB120-11424-0.025mg
NB120-11424
Bulk Order

Mouse S1P1/EDG-1 Antibody (713412) [Alexa Fluor® 488]
Catalog #: FAB7089G
(1)
Product Documents
Images (2)
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
Flow
Detection of S1P1/EDG-1 antibody in Mouse Thymocytes antibody by Flow Cytometry.
(2)
Catalog #
Availability
Size / Price
Qty
FAB7089G-100UG
Bulk Order

Mouse S1P1/EDG-1 Antibody (713412) [PE]
Catalog #: FAB7089P
Citations (12)
Product Documents
Images (2)
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
Flow
Detection of S1P1/EDG-1 antibody in HEK293 Human Cell Line Transfected with Mouse S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
(2)
Catalog #
Availability
Size / Price
Qty
FAB7089P-100UG
FAB7089P
Bulk Order

S1P1/EDG-1 Antibody (JM10-66)
Catalog #: NBP2-67129
Product Documents
Images (11)

Recombinant Monoclonal Antibody

Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #JM10-66
Applications:
IHC, WB, Flow, ICC/IF
Western Blot: S1P1/EDG-1 Antibody (JM10-66) [NBP2-67129]
(11)
Catalog #
Availability
Size / Price
Qty
NBP2-67129
Bulk Order

Sphingosine-1-phosphate
Catalog #: 1370
Citations (58)
Product Documents
Images (1)

Endogenous agonist at S1P1-5

Chemical Name:
(E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol
Purity:
≥98%
Endogenous agonist at S1P1-5
Catalog #
Availability
Size / Price
Qty
1370/1
Bulk Order

CS 2100
Catalog #: 4543
Citations (5)
Product Documents
Images (1)

Selective S1P1 agonist

Chemical Name:
1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid
Purity:
≥97%
Selective S1P1 agonist
Catalog #
Availability
Size / Price
Qty
4543/50
4543/10
Bulk Order

Mouse S1P1/EDG-1 Antibody (713412) [APC]
Catalog #: FAB7089A
(2)
Citations (11)
Product Documents
Images (2)
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
Flow
Detection of S1P1/EDG-1 antibody in HEK293 Human Cell Line Transfected with Mouse S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
(2)
Catalog #
Availability
Size / Price
Qty
FAB7089A
FAB7089A-100UG
Bulk Order

S1P1/EDG-1 Antibody
Catalog #: NBP2-27291
Product Documents
Images (1)
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC
Immunohistochemistry-Paraffin: S1P1/EDG-1 Antibody [NBP2-27291]
Catalog #
Availability
Size / Price
Qty
NBP2-27291
NBP2-27291SS
Bulk Order

FTY 720
Catalog #: 6176
Citations (31)
Product Documents
Images (1)

Potent S1P receptor agonist; also immunosuppressant

Alternate Names:
Fingolimod,Gilenya
Chemical Name:
2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride
Purity:
≥98%
Potent S1P receptor agonist; also immunosuppressant
Catalog #
Availability
Size / Price
Qty
6176/10
6176/50
Bulk Order

Human S1P1/EDG-1 Antibody (218713) [PE]
Catalog #: FAB2016P
Citations (8)
Product Documents
Images (1)

Clone 218713 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #218713
Applications:
Flow
Detection of S1P1/EDG-1 antibody in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
Catalog #
Availability
Size / Price
Qty
FAB2016P
Bulk Order

Mouse S1P1/EDG-1 Antibody (713412) [Alexa Fluor® 700]
Catalog #: FAB7089N
(1)
Product Documents
Images (2)
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
Flow
Detection of S1P1/EDG-1 antibody in HEK293 Human Cell Line Transfected with Mouse S1P1/EDG-1 and GFP antibody by Flow Cytometry.
(2)
Catalog #
Availability
Size / Price
Qty
FAB7089N
Bulk Order

SEW 2871
Catalog #: 2284
Citations (35)
Product Documents
Images (1)

Cell-permeable, selective S1P1 receptor agonist

Chemical Name:
5-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]1,2,4-oxadiazole
Purity:
≥98%
Cell-permeable, selective S1P1 receptor agonist
Catalog #
Availability
Size / Price
Qty
2284/10
2284/50
Bulk Order

Mouse S1P1/EDG-1 (NP_031927) VersaClone cDNA
Catalog #: RDC0053
Citations (2)
Product Documents
Images (1)
Reactivity:
Mouse
R&D Systems VersaClone cDNA Plasmids
Catalog #
Availability
Size / Price
Qty
RDC0053
Bulk Order

CYM 5442 hydrochloride
Catalog #: 3601
Citations (6)
Product Documents
Images (1)

Selective S1P1 receptor agonist

Chemical Name:
2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl amino) ethanol hydrochloride
Purity:
≥98%
Selective S1P1 receptor agonist
Catalog #
Availability
Size / Price
Qty
3601/10
3601/50
Bulk Order

W146
Catalog #: 3602
Citations (32)
Product Documents
Images (1)

Potent and selective S1P1 receptor antagonist

Alternate Names:
ML 056
Chemical Name:
[(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid
Purity:
≥98%
Potent and selective S1P1 receptor antagonist
Catalog #
Availability
Size / Price
Qty
3602/1
Bulk Order

VPC 23019
Catalog #: 4195
Citations (37)
Product Documents
Images (1)

S1P1 and S1P3 antagonist

Chemical Name:
2-Amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamaide
Purity:
≥95%
S1P1 and S1P3 antagonist
Catalog #
Availability
Size / Price
Qty
4195/10
Bulk Order

RP 001 hydrochloride
Catalog #: 4289
Citations (4)
Product Documents
Images (1)

Potent S1P1 agonist

Chemical Name:
N-[4-[5-[3-Cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine hydrochloride
Purity:
≥98%
Potent S1P1 agonist
Catalog #
Availability
Size / Price
Qty
4289/50
4289/10
Bulk Order

Ex 26
Catalog #: 5833
Citations (15)
Product Documents
Images (1)

Potent and selective S1P1 receptor antagonist

Chemical Name:
1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid
Purity:
≥98%
Potent and selective S1P1 receptor antagonist
Catalog #
Availability
Size / Price
Qty
5833/50
5833/10
Bulk Order

Human S1P1/EDG-1 Antibody (218713) [APC]
Catalog #: FAB2016A
Citations (2)
Product Documents
Images (1)

Clone 218713 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #218713
Applications:
Flow
Detection of S1P1/EDG-1 antibody in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
Catalog #
Availability
Size / Price
Qty
FAB2016A
Bulk Order

Mouse S1P1/EDG-1 (NP_031927) VersaClone cDNA
Catalog #: RDC0053
Citations (2)
Product Documents
Images (1)
Reactivity:
Mouse
R&D Systems VersaClone cDNA Plasmids
Catalog #
Availability
Size / Price
Qty
RDC0053
Bulk Order

TASP 0277308
Catalog #: 6498
Product Documents
Images (1)

Potent and selective S1P1 receptor antagonist; inhibits angiogenesis

Chemical Name:
3,4-Dichloro-N-[(1R)-1-[4-ethyl-5-[3-(4-methyl-1-piperazinyl)phenoxy]-4H-1,2,4-triazol-3-yl]ethyl]benzenesulfonamide
Purity:
≥98%
Potent and selective S1P1 receptor antagonist; inhibits angiogenesis
Catalog #
Availability
Size / Price
Qty
6498/5
Bulk Order

GSK 2018682
Catalog #: 6709
Product Documents
Images (1)

S1P1 and S1P5 agonist

Chemical Name:
4-[5-[5-Chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-1H-indole-1-butanoic acid
Purity:
≥98%
S1P1 and S1P5 agonist
Catalog #
Availability
Size / Price
Qty
6709/10
6709/50
Bulk Order

Ozanimod
Catalog #: 7663
Citations (5)
Product Documents
Images (1)

Potent and selective S1P1 and S1P5 agonist

Chemical Name:
5-[3-[(1S)-2,3-Dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)benzonitrile
Purity:
≥98%
Potent and selective S1P1 and S1P5 agonist
Catalog #
Availability
Size / Price
Qty
7663/10
7663/50
Bulk Order
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