ROR gamma/RORC/NR1F3: Small Molecules and Peptides
ROR gamma (Nuclear receptor ROR-gamma, RORC, NR1F3) is a DNA binding transcription factor that is a member of the NR1 nuclear hormone receptor family. Knockout mice implicate ROR gamma as being essential for lymphoid organogenesis and controlling apoptosis during thymopoiesis.
6 results for "ROR gamma/RORC/NR1F3 Small Molecules and Peptides" in Products
6 results for "ROR gamma/RORC/NR1F3 Small Molecules and Peptides" in Products
ROR gamma/RORC/NR1F3: Small Molecules and Peptides
ROR gamma (Nuclear receptor ROR-gamma, RORC, NR1F3) is a DNA binding transcription factor that is a member of the NR1 nuclear hormone receptor family. Knockout mice implicate ROR gamma as being essential for lymphoid organogenesis and controlling apoptosis during thymopoiesis.
Inhibits hepatitis C viral life cycle; also α-crystallin (cryAB) chaperone
| Chemical Name: | Cholest-5-ene-3β,25-diol |
| Purity: | ≥95% (HPLC) |
RORα/γ agonist
| Chemical Name: | N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)benzamide |
| Purity: | ≥98% (HPLC) |
T cell-specific RORγ (RORγt) agonist
| Chemical Name: | 2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide |
| Purity: | ≥98% (HPLC) |
RORγ antagonist; inhibits AR expression
| Chemical Name: | N-[2'-Fluoro-4'-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1'biphenyl]-4-yl]-2-nitrobenzeneacetamide |
| Purity: | ≥98% (HPLC) |
Selective RORγ inverse agonist
| Chemical Name: | 2-Fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-a,a-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol |
| Purity: | ≥98% (HPLC) |
RORγt inverse agonist; suppresses Th17 cell differentiation
| Chemical Name: | 3-(1,3-Benzodioxol-5-yl)-1-(cis-3,5-dimethyl-1-piperidinyl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-propanone |
| Purity: | ≥98% (HPLC) |
