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26 results for "GABA A R alpha 3" in Products

GABA A R alpha 3 Products

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six ...

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Competitive and selective GABAA antagonist

Potent GABAA agonist; also GABAA-ρ partial agonist

Positive allosteric modulator of GABAA receptors

Benzodiazepine inverse agonist

GABAA partial agonist; acts at benzodiazepine site

GABAA agonist

Postitive allosteric modulator of GABAA receptors

Benzodiazepine partial inverse agonist

Benzodiazepine antagonist

α5-selective GABAA inverse agonist

GABAA partial agonist; displays subtype selectivity

Active metabolite of oxcarbazepine (Cat. No. 3864)

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