DMCM hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 3083
Benzodiazepine inverse agonist
Key Product Details
Description
Benzodiazepine inverse agonist
Product Description
DMCM hydrochloride is a benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity.Product Specifications
Molecular Weight
350.80
Formula
C17H18N2O4.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
4-Ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester hydrochloride
CAS Number
1215833-62-7
PubChem ID
45261899
InChI Key
FHCRBVQGMZUJKY-UHFFFAOYSA-N
SMILES
CCC1=C(C(OC)=O)N=CC3=C1C2=CC(OC)=C(OC)C=C2N3.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 31.43 | 100 | |
| DMSO | 7.02 | 20 |
Preparing Stock Solutions
for DMCM hydrochloride
The following data is based on the product molecular weight 350.80
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.85 mL | 14.25 mL | 28.51 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.70 mL |
| 10 mM | 0.29 mL | 1.43 mL | 2.85 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.57 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Conto Behavioral differences between subgroups of rats with high and low threshold to clonic convulsions induced by DMCM, a benzodiazepine inverse agonist. Pharmacol.Biochem.Behav. 2005 PMID: 16297441
- Sieve Pain and negative affect: evidence the inverse benzodiazepine agonist DMCM inhibits pain and learning in rats. Psychopharmacol. 2001 PMID: 11205417
- Petersen DMCM: a potent convusive benzodiazepine receptor ligand. Eur.J.Pharmacol. 1983 PMID: 6317396
Product Specific Notices for DMCM hydrochloride
For research use only
Loading...
Loading...