ErbB2/Her2 Products
ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in development, cancer, communication at the neuromuscular junction, and regulation of cell growth and differentiation. The ErbB2/ErbB3 heterodimer is expressed in the majority of breast, skin, ovary and gastrointestinal tumors and transduces a highly mitogenic signal in response to neuregulin 1 (NRG1; heuregulin 1) or NRG2. ErbB3, ErbB2 and neuregulin are all required for formation of the sympathetic nervous system.
1468 results for "ErbB2/Her2" in Products
1468 results for "ErbB2/Her2" in Products
ErbB2/Her2 Products
ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in development, cancer, communication at the neuromuscular junction, and regulation of cell growth and differentiation. The ErbB2/ErbB3 heterodimer is expressed in the majority of breast, skin, ovary and gastrointestinal tumors and transduces a highly mitogenic signal in response to neuregulin 1 (NRG1; heuregulin 1) or NRG2. ErbB3, ErbB2 and neuregulin are all required for formation of the sympathetic nervous system.
| Source: | NS0 |
| Accession #: | NP_004439 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu5 |
| Applications: | Flow, CyTOF-ready, InhibCellGro |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #191924 |
| Applications: | WB, Flow, IHC, CyTOF-ready, ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready, InhibCellGro |
| Source: | HEK293 |
| Accession #: | P04626-1 |
| Applications: | BA |
| Sensitivity: | 14.8 pg/mL |
| Applications: | ELISA |
| Assay Range: | 78.1 - 5,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine, Human Milk) |
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ERBB2/8142R |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ERBB2/8142R |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rERBB2/6637 |
| Applications: | IHC |
![ErbB2/Her2 Antibody (rERBB2/6637) Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (rERBB2/6637) [NBP3-23581] -](https://resources.bio-techne.com/images/products/nbp3-23581_mouse-erbb2-her2-mab-rerbb2-6637-2412025872320.jpg "Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (rERBB2/6637) [NBP3-23581] -")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rERBB2/6637 |
| Applications: | IHC |
![ErbB2/Her2 Antibody (rERBB2/6637) - Azide and BSA Free Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (rERBB2/6637) - Azide and BSA Free [NBP3-24341] -](https://resources.bio-techne.com/images/products/nbp3-24341_mouse-erbb2-her2-mab-rerbb2-6637-azide-and-bsa-free-24120257595037.jpg "Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (rERBB2/6637) - Azide and BSA Free [NBP3-24341] -")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ERBB2/7158R |
| Applications: | IHC |
![ErbB2/Her2 Antibody (ERBB2/7158R) Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (ERBB2/7158R) [NBP3-23595] -](https://resources.bio-techne.com/images/products/nbp3-23595_rabbit-erbb2-her2-mab-erbb2-7158r-2412025872385.jpg "Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (ERBB2/7158R) [NBP3-23595] -")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ERBB2/7158R |
| Applications: | IHC |
![ErbB2/Her2 Antibody (ERBB2/7158R) - Azide and BSA Free Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (ERBB2/7158R) - Azide and BSA Free [NBP3-24037] -](https://resources.bio-techne.com/images/products/nbp3-24037_rabbit-erbb2-her2-mab-erbb2-7158r-azide-and-bsa-free-2412025759280.jpg "Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (ERBB2/7158R) - Azide and BSA Free [NBP3-24037] -")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rERBB2/9401 |
| Applications: | IHC |
![ErbB2/Her2 Antibody (rERBB2/9401) - Azide and BSA Free Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (rERBB2/9401) - Azide and BSA Free [NBP3-24036] -](https://resources.bio-techne.com/images/products/nbp3-24036_mouse-erbb2-her2-mab-rerbb2-9401-azide-and-bsa-free-2412025801666.jpg "Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (rERBB2/9401) - Azide and BSA Free [NBP3-24036] -")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rERBB2/9401 |
| Applications: | IHC |
![ErbB2/Her2 Antibody (rERBB2/9401) Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (rERBB2/9401) [NBP3-23594] -](https://resources.bio-techne.com/images/products/nbp3-23594_mouse-erbb2-her2-mab-rerbb2-9401-2412025863646.jpg "Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody (rERBB2/9401) [NBP3-23594] -")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rERBB2/9401 |
| Applications: | IHC |
![ErbB2/Her2 Antibody (rERBB2/9401) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-24036cl1_mouse-erbb2-her2-mab-rerbb2-9401-corafluor-1-29102025128208.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ERBB2/8142R |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rERBB2/9401 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ERBB2/7158R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rERBB2/6637 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ERBB2/7158R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rERBB2/6637 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ERBB2/8142R |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ERBB2/7158R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #rERBB2/6637 |
| Applications: | IHC |