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5 results for "ErbB2/Her2 Proteome Profiler Antibody Arrays" in Products
ErbB2/Her2 Proteome Profiler Antibody Arrays
ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in ...
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #290814
Applications:
IHC, WB
Alternate Names:
SU 11248
Chemical Name:
N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt
Purity:
≥98%
Reactivity:
Human
