EGF Receptor Inhibitors: Small Molecules and Peptides
21 results for "EGF Receptor Inhibitors Small Molecules and Peptides" in Products
21 results for "EGF Receptor Inhibitors Small Molecules and Peptides" in Products
EGF Receptor Inhibitors: Small Molecules and Peptides
Orally active, selective EGFR inhibitor
| Alternate Names: | Gefitinib,ZD 1839 |
| Chemical Name: | N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine |
| Purity: | ≥98% (HPLC) |
Potent irreversible pan ErbB inhibitor
| Alternate Names: | PF00299804 |
| Chemical Name: | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide |
| Purity: | ≥98% (HPLC) |
Highly potent EGFR-kinase inhibitor
| Alternate Names: | Tyrphostin AG 1478 |
| Chemical Name: | N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine hydrochloride |
| Purity: | ≥98% (HPLC) |
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
| Alternate Names: | Tyrphostin AG 490 |
| Chemical Name: | (E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide |
| Purity: | ≥98% (HPLC) |
Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
| Chemical Name: | (2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide |
| Purity: | ≥98% (HPLC) |
Potent and selective ErbB2 inhibitor
| Chemical Name: | N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine |
| Purity: | ≥98% (HPLC) |
Potent mutant-selective EGFR inhibitor
| Chemical Name: | N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide |
| Purity: | ≥98% (HPLC) |
Potent ErbB receptor family inhibitor
| Chemical Name: | N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine |
| Purity: | ≥98% (HPLC) |
Potent ErbB receptor family inhibitor
| Chemical Name: | 5E-4-Amino-6-(4-benzyloxy-3-chlorophenylamino)pyrimidine-5-carboxaldehyde N-(2-morpholin-4-ylethyl) oxime hydrochloride |
| Purity: | ≥97% (HPLC) |
Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
| Chemical Name: | (4-Fluorophenyl)methyl N-[2-[(1-methyl-1H-pyrazol-4-yl)amino]-4-pyrimidinyl]-N-[3-[(1-oxo-2-propen-1-yl)amino]phenyl]carbamate |
| Purity: | ≥98% (HPLC) |
Potent, reversible EGFR tyrosine kinase inhibitor
| Chemical Name: | N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent dual specificity EGFR/HER2 inhibitor; active in vivo
| Alternate Names: | BIBW2992 |
| Chemical Name: | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide dimaleate |
| Purity: | ≥98% (HPLC) |
EGFR kinase inhibitor. Also estrogen and PPARγ ligand
| Chemical Name: | 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity
| Chemical Name: | N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine |
| Purity: | ≥98% (HPLC) |
Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor
| Chemical Name: | N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine |
| Purity: | ≥98% (HPLC) |
Potent EGFR and VEGFR inhibitor
| Chemical Name: | 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
Negative control for PP 2 (Cat. No. 1407)
| Chemical Name: | 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
Potent dual EGFR/ErbB2 inhibitor; orally active
| Chemical Name: | N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[2-[[[2-(methylsulfonyl)ethyl]amino]methyl]-4-thiazolyl]-4-quinazolinamine dihydrochloride |
| Purity: | ≥97% (HPLC) |
Potent EGFR kinase inhibitor
| Alternate Names: | CI 1033,PD 183805 |
| Chemical Name: | N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective ErbB2 inhibitor
| Alternate Names: | Mubritinib |
| Chemical Name: | 1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole |
| Purity: | ≥98% (HPLC) |
Potent mutant-selective EGFR inhibitor
| Chemical Name: | N-[3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide |
| Purity: | ≥98% (HPLC) |
