11 results for "Akt Small Molecules and Peptides" in Products
Akt: Small Molecules and Peptides
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
| Chemical Name: | 6-(2-Benzothiazolyl)-1-ethyl-2-[(1E)-2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide |
| Purity: | ≥98% (HPLC) |
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
| Chemical Name: | 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one |
| Purity: | ≥98% (HPLC) |
Akt activator
| Chemical Name: | 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester |
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
| Alternate Names: | Triciribine,NSC 154020,TCN |
| Chemical Name: | 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine |
| Purity: | ≥98% (HPLC) |
Potent and selective dual Akt1 and 2 inhibitor
| Alternate Names: | Akt Inhibitor VIII |
| Chemical Name: | 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Purity: | ≥98% (HPLC) |
Selective Akt/PKB inhibitor
| Alternate Names: | Akt Inhibitor X |
| Chemical Name: | 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent pan-Akt and PKA inhibitor
| Chemical Name: | 4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine hydrochloride |
| Purity: | ≥98% (HPLC) |
AKT kinase Degrader (PROTAC®)
| Chemical Name: | 4-Amino-N-((S)-1-(4-chlorophenyl)-3-(4-(12-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-12-oxododecanoyl)piperazin-1-yl)propyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide |
| Purity: | ≥97% (HPLC) |
PKB/Akt inhibitor; also modulates Kv2.1 current
| Alternate Names: | KRX-0401 |
| Chemical Name: | Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate |
| Purity: | ≥98% (HPLC) |
Akt kinase inhibitor. Antitumor
| Chemical Name: | 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol |
| Purity: | ≥98% (HPLC) |
SPOP E3 ubiquitin ligase inhibitor
| Chemical Name: | 1,5-Dihydro-2-imino-10-methyl-N-[2-(4-methyl-1-piperazinyl)ethyl]-5-oxo-1-[2-(2-thienyl)ethyl]-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide |
| Purity: | ≥98% (HPLC) |
