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Additional Transcription Factor Compounds Products

18 results for "Additional Transcription Factor Compounds" in Products

18 results for "Additional Transcription Factor Compounds" in Products

Additional Transcription Factor Compounds Products

Core binding factor inhibitor; attenuates hematopoiesis

Alternate Names: CBF&#946-Runx1 inhibitor II
Chemical Name: 7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one
Purity: ≥98% (HPLC)
Core binding factor inhibitor; attenuates hematopoiesis

GLI antagonist; inhibits Hedgehog (Hh) signaling

Chemical Name: 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine
Purity: ≥98% (HPLC)
GLI antagonist; inhibits Hedgehog (Hh) signaling

Potent and selective CREB inhibitor

Chemical Name: 3-(3-Aminopropoxy)-N-[2-[[3-[[(4-chloro-2-hydroxyphenyl)amino]carbonyl]-2-naphthalenyl]oxy]ethyl]-2-naphthalenecarboxamide hydrochloride
Purity: ≥98% (HPLC)
Potent and selective CREB inhibitor

Hepatocyte nuclear factor 4α (HNF4α) antagonist

Chemical Name: 2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole
Purity: ≥98% (HPLC)
Hepatocyte nuclear factor 4α (HNF4α) antagonist

Brachyury down modulator

Chemical Name: (E)-4-(Dimethylamino)-N-[1-[4-fluoro-3-(2,2,2-trifluoroethoxy)anilino]-6-methoxy-7-isoquinolyl]but-2-enamide
Purity: ≥98% (HPLC)
Brachyury down modulator

Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Chemical Name: 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline hydrochloride
Purity: ≥97% (HPLC)
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

YAP inhibitor

Alternate Names: Visudyne
Chemical Name: (4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester
Purity: ≥95% (HPLC)
YAP inhibitor

High affinity Nur77 agonist

Chemical Name: Ethyl 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetate
Purity: ≥98% (HPLC)
High affinity Nur77 agonist

TRIM24 Degrader (PROTAC®)

Chemical Name: (2S,4R)-1-((S)-15-(tert-Butyl)-1-(3-(N-(1,3-dimethyl-2-oxo-6-(3-propoxyphenoxy)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)sulfamoyl)phenyl)-1,13-dioxo-5,8,11-trioxa-2,14-diazahexadecan-16-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98% (HPLC)
TRIM24 Degrader (PROTAC®)

Cryptochrome protein stabilizer; lengthens circadian period

Chemical Name: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)methanesulfonamide
Purity: ≥98% (HPLC)
Cryptochrome protein stabilizer; lengthens circadian period

High affinity Myc inhibitor

Chemical Name: 4-[2-(2-Furanyl)-6-(4-nitrophenyl)-4-pyridinyl]benzamide
Purity: ≥98% (HPLC)
High affinity Myc inhibitor

Steroid receptor coactivator 3 (SRC-3) inhibitor

Chemical Name: 1-(2-Pyridinyl)ethanone 2-(1-methyl-1H-benzimidazol-2-yl)hydrazone hydrochloride
Purity: ≥98% (HPLC)
Steroid receptor coactivator 3 (SRC-3) inhibitor

Selective inhibitor of ATF6α; sensitizes cells to ER stress

Chemical Name: N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide
Purity: ≥98% (HPLC)
Selective inhibitor of ATF6α; sensitizes cells to ER stress

Potent and selective Foxo1 inhibitor; orally bioavailable

Chemical Name: 5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Purity: ≥98% (HPLC)
Potent and selective Foxo1 inhibitor; orally bioavailable

Potent pan-TEAD inhibitor

Chemical Name: N-[(1S)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide
Purity: ≥98% (HPLC)
Potent pan-TEAD inhibitor

Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling

Chemical Name: 4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide
Purity: ≥98% (HPLC)
Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling

Inhibits c-Myc-Max dimerization

Chemical Name: 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
Purity: ≥98% (HPLC)
Inhibits c-Myc-Max dimerization

YAP inhibitor

Purity: ≥95% (HPLC)
Peptide inhibitor of YAP signaling
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