14 results for "ROCK1 Small Molecules and Peptides" in Products
ROCK1 Small Molecules and Peptides
Rho-associated kinase I (ROCK1, ROK beta, p160ROCK) is a serine-threonine protein kinase and an effector of the small GTPase Rho. With N-terminus protein kinase domain and C-terminus Rho-binding domain/pleckstrin homology domain, ROCK1 can be activated by either RhoA or RhoB. In Rho specific ROCK1 activation, a Rho protein binds to the Rho-binding domain and induces a conformational change which opens the kinase domain for the phosphorylation of downstream effectors (1). Activated ROCK1 ...
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
Y-27632 synthesized to cGMP guidelines
Selective Rho-kinase (ROCK) inhibitor
ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs
Inhibitor of cyclic nucleotide dependent- and Rho-kinases
Potent and selective ROCK inhibitor
Selective Rho-kinase (ROCK) inhibitor. More selective analog of H 1152 dihydrochloride (Cat. No. 2414)
Potent Rho-kinase inhibitor; vasodilator
Potent and highly selective ROCK inhibitor; orally active
Potent and highly selective ROCK inhibitor; orally active
Potent and highly selective ROCK inhibitor; orally active
Potent and selective LIMK inhibitor; antitumor
Sterile-filtered 10 mM solution of Y-27632, selective ROCK inhibitor, pre-dissolved in water
Potent and selective LIMK inhibitor; antitumor