177 results for "ROCK1" in Products
ROCK1 Products
Rho-associated kinase I (ROCK1, ROK beta, p160ROCK) is a serine-threonine protein kinase and an effector of the small GTPase Rho. With N-terminus protein kinase domain and C-terminus Rho-binding domain/pleckstrin homology domain, ROCK1 can be activated by either RhoA or RhoB. In Rho specific ROCK1 activation, a Rho protein binds to the Rho-binding domain and induces a conformational change which opens the kinase domain for the phosphorylation of downstream effectors (1). Activated ROCK1 ...
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
| Alternate Names: | y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor |
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Y-27632 synthesized to cGMP guidelines
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥99% |
| Reactivity: | Human, Mouse, Rat, Canine, Primate, +1 More |
| Details: | Mouse IgG Monoclonal Clone #154C1465 |
| Applications: | WB, ICC/IF |
![Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)BSA Free [NB100-56596]](https://resources.bio-techne.com/images/products/cleaved-ROCK1-Antibody-154C1465-Western-Blot-NB100-56596-img0004.jpg "Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)BSA Free [NB100-56596]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: ROCK1 Antibody [NB100-624]](https://resources.bio-techne.com/images/products/ROCK1-Antibody-NB100-624-img0003.jpg "Western Blot: ROCK1 Antibody [NB100-624]")
Catalog #:
FAB4590G
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #261 |
| Applications: | WB |
![Western Blot: ROCK1 Antibody (261) [NBP2-42917]](https://resources.bio-techne.com/images/products/ROCK1-Antibody-261-Western-Blot-NBP2-42917-img0005.jpg "Western Blot: ROCK1 Antibody (261) [NBP2-42917]")
| Reactivity: | Human, Mouse, Rat, Canine, Primate, +1 More |
| Details: | Mouse IgG Monoclonal Clone #154C1465 |
| Applications: | WB, ICC/IF |
![Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)Azide Free [NBP2-33238]](https://resources.bio-techne.com/images/products/cleaved-ROCK1-Antibody-154C1465-Azide-Free-Western-Blot-NBP2-33238-img0001.jpg "Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)Azide Free [NBP2-33238]")
Catalog #:
FAB4590X
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
Catalog #:
FAB4590T
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Mycoplasma |
![Western Blot: ROCK1 Antibody [NBP1-82450]](https://resources.bio-techne.com/images/products/ROCK1-Antibody-Western-Blot-NBP1-82450-img0008.jpg "Western Blot: ROCK1 Antibody [NBP1-82450]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, KO |
| Source: | Sf 9 (baculovirus) |
| Accession #: | NM_005406 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2E2 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: ROCK1 Antibody (2E2) [H00006093-M01]](https://resources.bio-techne.com/images/products/ROCK1-Antibody-2E2-Western-Blot-H00006093-M01-img0008.jpg "Western Blot: ROCK1 Antibody (2E2) [H00006093-M01]")
Catalog #:
FAB4590V
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
Catalog #:
FAB4590S
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
Catalog #:
FAB4590U
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
Catalog #:
FAB4590N
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
Catalog #:
FAB4590R
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #464 |
| Applications: | WB |
![Western Blot: ROCK1 Antibody (464) [NBP2-42918]](https://resources.bio-techne.com/images/products/ROCK1-Antibody-464-Western-Blot-NBP2-42918-img0004.jpg "Western Blot: ROCK1 Antibody (464) [NBP2-42918]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: ROCK1 Antibody [NBP2-19297]](https://resources.bio-techne.com/images/products/ROCK1-Antibody-Western-Blot-NBP2-19297-img0001.jpg "Western Blot: ROCK1 Antibody [NBP2-19297]")
Catalog #:
NBP3-50801
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #24GB4530 |
| Applications: | WB, ICC/IF, Flow |
Catalog #:
FAB4590AFP488
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
Catalog #:
FAB4590AFP647
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
Catalog #:
FAB4590AFP680
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |