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PDGF-BB Products

PDGF-BB (Platelet-Derived Growth Factor BB) is a homodimeric molecule expressed by hepatocytes and nonresorbing osteoclasts, and it promotes osteoblast development and bone formation. It is also produced by platelets, macrophages, and mast cells. At sites of injury, it promotes neutrophil and macrophage infiltration for debridement, fibroblast secretion of new extracellular matrix, and IGF-I-mediated re-epithelialization. The traditional receptor for PDGF is either a homodimer or heterodimer created from two type I transmembrane RTKs, PDGF R alpha and PDGF R beta. PDGF-BB has been shown to bind the alpha/alpha homodimer, alpha/beta heterodimer, and the beta/beta homodimer in vitro, and act through the beta/beta homodimer in vivo.

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57 results for "PDGF-BB" in Products

57 results for "PDGF-BB" in Products

PDGF-BB Products

PDGF-BB (Platelet-Derived Growth Factor BB) is a homodimeric molecule expressed by hepatocytes and nonresorbing osteoclasts, and it promotes osteoblast development and bone formation. It is also produced by platelets, macrophages, and mast cells. At sites of injury, it promotes neutrophil and macrophage infiltration for debridement, fibroblast secretion of new extracellular matrix, and IGF-I-mediated re-epithelialization. The traditional receptor for PDGF is either a homodimer or heterodimer created from two type I transmembrane RTKs, PDGF R alpha and PDGF R beta. PDGF-BB has been shown to bind the alpha/alpha homodimer, alpha/beta heterodimer, and the beta/beta homodimer in vitro, and act through the beta/beta homodimer in vivo.

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Source: E. coli
Accession #: P01127.1
Applications: BA
Recombinant Human PDGF-BB Protein Bioactivity
(2)

Animal-Free

Source: E. coli
Accession #: P01127
Applications: BA
Recombinant Human PDGF-BB GMP Protein Bioactivity
(2)
Sensitivity: 15 pg/mL
Applications: ELISA
Assay Range: 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Human PDGF-BB ELISA Cell Culture Supernate Standard Curve
(3)

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.
(3)
Assay Range: 31.2 - 2,000 pg/mL
Applications: ELISA
Human PDGF-BB ELISA Standard Curve

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Detection of selected mouse cytokines in Balb/3T3 Cell Line Lysate
(3)
Source: E. coli
Accession #: Q05028.1
Applications: BA
Graph showing dose-dependent bioactivity of rat PDGF-BB protein

Simple Plex Human PDGF-BB assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Simple Plex
Human PDGF-BB Simple Plex Assay
(3)

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Applications: NULL
NHP Luminex Standard Curves (Cell Culture Supernates)
(2)

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Profiling Angiogenesis-Related Proteins in Human Cancer Tissues.
(3)

Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.

Applications: Simple Plex
Custom Simple Plex Assay Panel
Sensitivity: 19.3 pg/mL
Applications: ELISA
Assay Range: 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Mouse/Rat PDGF-BB ELISA Cell Culture Supernate Standard Curve
(4)

Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies

The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.
(4)
Assay Range: 62.5 - 4,000 pg/mL
Applications: ELISA
Mouse / Rat PDGF-BB ELISA Standard Curve
Reactivity: Human
Details: Goat IgG Polyclonal
Applications: WB, Neut
Cell Proliferation Induced by PDGF‑BB and Neutralization by Human PDGF‑BB Antibody.
Source: E. coli
Accession #: P01127.1
Applications: BA
Recombinant Human PDGF-BB, Biotinylated Protein Bioactivity

Intended for preclinical researchers who may transition to GMP PDGF-BB for their clinical work

Source: E. coli
Accession #: P01127.1
Applications: BA
R&D Systems Animal-Free Recombinant Proteins

Control for use with Human and Non-Human Primate PDGF-BB Simple Plex Cartridge Kit

Applications: Ctrl, Simple Plex

Simple Plex Non-Human Primate PDGF-BB assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Simple Plex
(3)

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Source: CHO
Accession #: P01127.1
Applications: BA
(2)
Source: E. coli
Accession #: XP_005606703
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
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