NMDA Receptor Antagonists: Small Molecules and Peptides
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity.
33 results for "NMDA Receptor Antagonists Small Molecules and Peptides" in Products
33 results for "NMDA Receptor Antagonists Small Molecules and Peptides" in Products
NMDA Receptor Antagonists: Small Molecules and Peptides
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity.
Potent and selective NMDA receptor antagonist; more active form of DL-AP5
| Alternate Names: | 2-APV,D-APV,D-2-amino-5-phosphonovalerate |
| Chemical Name: | D-(-)-2-Amino-5-phosphonopentanoic acid |
| Purity: | ≥98% (HPLC) |
Non-competitive NMDA receptor antagonist
| Chemical Name: | 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective NMDA antagonist
| Alternate Names: | DL-APV |
| Chemical Name: | DL-2-Amino-5-phosphonopentanoic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective non-NMDA iGluR antagonist
| Alternate Names: | Cyanquixaline |
| Chemical Name: | 6-Cyano-7-nitroquinoxaline-2,3-dione |
| Purity: | ≥98% (HPLC) |
Non-competitive NMDA antagonist; acts at ion channel site
| Alternate Names: | Dizocilpine |
| Chemical Name: | (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate |
| Purity: | ≥98% (HPLC) |
Potent and selective NMDA antagonist; sodium salt of DL-AP5
| Chemical Name: | DL-2-Amino-5-phosphonopentanoic acid sodium salt |
| Purity: | ≥98% (HPLC) |
GluN2B-selective NMDA antagonist
| Chemical Name: | (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate |
| Purity: | ≥98% (HPLC) |
NMDA antagonist; acts at ion channel site
| Chemical Name: | 3,5-Dimethyl-tricyclo[3.3.1.13,7]decan-1-amine hydrochloride |
Highly potent NMDA antagonist
| Chemical Name: | trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline |
| Purity: | ≥98% (HPLC) |
Non-competitive NMDA antagonist; also σ ligand
| Chemical Name: | (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemi-(DL)-tartrate |
| Purity: | ≥98% (HPLC) |
Potent NMDA antagonist; more active enantiomer of (RS)-CPP
| Chemical Name: | 3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid |
Potent and selective NMDA antagonist; acts at glycine site
| Alternate Names: | PAMQX |
| Chemical Name: | [(1S)-1-[[(7-Bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]phosphonic acid hydrochloride |
| Purity: | ≥98% (HPLC) |
GluN1/GluN2A-selective NMDA antagonist
| Chemical Name: | 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
KV7 channel activator; also GABAA modulator and indirect NMDA antagonist
| Alternate Names: | D 9998 |
| Chemical Name: | N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate |
| Purity: | ≥98% (HPLC) |
Non-competitive and GluN2C/GluN2D-selective NMDA antagonist
| Chemical Name: | 4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)quinazolinyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
NMDA antagonist; less active enantiomer of (+)-MK 801
| Chemical Name: | (5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylcohepten-5,10-imine maleate |
| Purity: | ≥98% (HPLC) |
Potent and GluN2A-selective NMDA antagonist
| Chemical Name: | [[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium salt |
| Purity: | ≥98% (HPLC) |
GluN2B-selective NMDA antagonist
| Alternate Names: | PD 174494,Ro 63-1908 |
| Chemical Name: | 1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent NMDA antagonist, acts at glycine site; sodium salt of 5,7-Dichlorokynurenic acid
| Chemical Name: | 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid sodium salt |
| Purity: | ≥98% (HPLC) |
Potent and noncompetitive NMDA antagonist
| Alternate Names: | CNS 1102 |
| Chemical Name: | N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent NMDA antagonist
| Chemical Name: | (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid |
Potent and selective NMDA antagonist
| Chemical Name: | (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective NMDA antagonist; less active form of DL-AP5
| Chemical Name: | L-(+)-2-Amino-5-phosphonopentanoic acid |
| Purity: | ≥98% (HPLC) |
GluN2C/GluN2D-selective NMDA antagonist
| Chemical Name: | (2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid |
| Purity: | ≥98% (HPLC) |
Potent competitive NMDA antagonist
| Alternate Names: | Midafotel,SDZ EAA 494 |
| Chemical Name: | D-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid |
