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DL-AP5

Catalog # 0105 | Tocris Bioscience a Bio-Techne Brand
Potent and selective NMDA antagonist
Potent and selective NMDA antagonist
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Key Product Details

Description: Potent and selective NMDA antagonist
Alternative Names: DL-APV
Chemical Name: DL-2-Amino-5-phosphonopentanoic acid
Purity: ≥98% (HPLC)
Molecular Weight: 197.13

Citations for DL-AP5 (90)

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Customer Reviews for DL-AP5 (3)

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  • AP5 action at NMDARs
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: Hypothalamus
    AP5 was in use as a control pharmacological intervention to prove NMDAR-related nature of the registered whole-cell electrophysiological response. 20 microM/l AP5 supressed the response immediately. Red trace: whole-cell response without AP5; black trace: after AP5 application.
    Needs stirring to be diluted.
    DL-AP5 Serum 0105
  • NMDA antagonist
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Blocks NMDA currents as expected
  • blocks within 5 minutes
    Name: Erik Dustrude
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: amygdala neurons
    50uM used to antagonize NMDA receptors to isolate AMPA current.
    5 minutes perfusion at ~1.5ml/min was sufficient for the full effect.
    DL-AP5 Serum 0105

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Product Documents for DL-AP5

Certificate of Analysis

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