CGP 37849
Tocris Bioscience, part of Bio-Techne | Catalog # 1469
Potent and selective NMDA antagonist
Key Product Details
Description
Potent and selective NMDA antagonist
Product Description
CGP 37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). Anticonvulsive following oral administration in vivo.Product Specifications
Molecular Weight
209.14
Formula
C6H12NO5P
Storage
Desiccate at +4°C
Purity
≥98% (HPLC)
Chemical Name
(E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid
CAS Number
127910-31-0
PubChem ID
5950212
InChI Key
BDYHNCZIGYIOGJ-DUXPYHPUSA-N
SMILES
NC(C(O)=O)/C=C(C)/CP(O)(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Background References
References are publications that support the biological activity of the product.
- Loscher and Honack Anticonvulsant and behavioural effects of two novel competitive N-MthD.-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamaz. J.Pharmacol.Exp.Ther. 1991 PMID: 1671593
- Pozza Electrophysiological characterization of a novel potent and orally active NMDA receptor antagonist: CGP 37849 and its ethylester CGP 39551. Eur.J.Pharmacol. 1990 PMID: 1976098
- Fagg CGP 37849 and CGP 39551: novel and potent competitive N-MthD.-asparate receptor antagonists with oral activity. Br.J.Pharmacol. 1990 PMID: 1972895
Product Specific Notices for CGP 37849
For research use only
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