CGP 37849

Name: CGP 37849
Brand: Tocris Bioscience
SKU: 1469

Tocris Bioscience, part of Bio-Techne | Catalog # 1469

Citations (17)

COA / SDS

Potent and selective NMDA antagonist

Key Product Details

Description:	Potent and selective NMDA antagonist
Chemical Name:	(E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid
Purity:	≥98% (HPLC)
Molecular Weight:	209.14

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Technical Data
Citations

Biological Activity for CGP 37849

CGP 37849 is a potent, selective and competitive NMDA receptor antagonist (K_i = 35 nM). Anticonvulsive following oral administration in vivo.

Technical Data for CGP 37849

M. Wt	209.14
Formula	C₆H₁₂NO₅P
Storage	Desiccate at +4°C
Purity	≥98% (HPLC)
CAS Number	127910-31-0
PubChem ID	5950212
InChi Key	BDYHNCZIGYIOGJ-DUXPYHPUSA-N
Smiles	NC(C(O)=O)/C=C(C)/CP(O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for CGP 37849

References are publications that support the biological activity of the product.

Loscher and Honack Anticonvulsant and behavioural effects of two novel competitive N-MthD.-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamaz. J.Pharmacol.Exp.Ther. 1991 PMID: 1671593
Pozza Electrophysiological characterization of a novel potent and orally active NMDA receptor antagonist: CGP 37849 and its ethylester CGP 39551. Eur.J.Pharmacol. 1990 PMID: 1976098
Fagg CGP 37849 and CGP 39551: novel and potent competitive N-MthD.-asparate receptor antagonists with oral activity. Br.J.Pharmacol. 1990 PMID: 1972895

CGP 37849

Tocris Bioscience, part of Bio-Techne | Catalog # 1469

Key Product Details

Biological Activity for CGP 37849

Technical Data for CGP 37849

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for CGP 37849

Product Documents for CGP 37849

COA

Certificate of Analysis

SDS

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