5 results for "Monoacylglycerol Lipase Inhibitors Small Molecules and Peptides" in Products
Monoacylglycerol Lipase Inhibitors: Small Molecules and Peptides
Monoacylglycerol lipase (MAGL, MGL, α/β-hydrolase domain-containing 6 acylglycerol lipase) is a serine hydrolase that breaks down monoacylglycerols to glycerol and fatty acid. It is the primary enzyme responsible for the metabolism of 2-arachidonylglycerol (2-AG) in the brain, and is also involved in lipid signaling.
2-AG acts as an endocannabinoid - an endogenous agonist of GPR55, CB1 and CB2 receptors. MAGL hydrolyzes 2-AG, attenuating endocannabinoid signaling and also generating ...
| Chemical Name: | 4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic acid 4-nitrophenyl ester |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 4-[Bis(1,3-benzodioxol-5-yl)methyl]-1-piperidinyl]-1H-1,2,4-triazol-1-yl-methanone |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4-triazol-1-yl)methanone |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 4-[(3-Phenoxyphenyl)methyl]-1-piperazinecarboxylic acid 4-nitrophenyl ester |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic acid 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester |
| Purity: | ≥98% (HPLC) |
