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IL-18/IL-1F4 Products
IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.
69 results for "IL-18/IL-1F4" in Products
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IL-18/IL-1F4 Products
IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.
69 results for "IL-18/IL-1F4" in Products
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
BA
| Source : | E. coli |
| Accession # : | Q14116 |
| Applications : | Bioactivity |
Catalog #:
SPCKB-PS-000501
Simple Plex automated IL-6 ELISA kit for use with human CCS/Plasma/Serum/CSF/BALF. Includes wash buffer and sample
Catalog #:
LXSAPM
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
ELISA
| Sensitivity : | 5.15 pg/mL |
| Assay Range : | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine) |
| Applications : | ELISA |
Catalog #:
B001-5
BA
A New rh IL-18 is Now Available! Competitively priced; Higher purity; Lower endotoxin; Manufactured in-house!
ELISA
| Assay Range : | 11.7 - 750 pg/mL |
| Applications : | ELISA |
BA
| Source : | E. coli |
| Accession # : | P70380 |
| Applications : | Bioactivity |
ELISA
| Sensitivity : | 25 pg/mL |
| Assay Range : | 25.6 - 1,000 pg/mL |
| Applications : | ELISA |
WB, Simple Western, ELISA, ICC, KO, Neut
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, ELISA, Immunocytochemistry/Immunofluorescence, Knockout Validated, Simple Western, Western Blot |
Catalog #:
D044-3
IP, Neut
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #125-2H |
| Applications : | Block/Neutralize, ELISA Capture, Immunoprecipitation |
ELISA
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
Catalog #:
DY7625-05
ELISA
| Assay Range : | 46.9 - 3,000 pg/mL |
| Applications : | ELISA |
Catalog #:
MAB91244
ELISA
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #1072H |
| Applications : | ELISA |
Catalog #:
7620
ELISA
Human IL-18/IL-1F4 Quantikine ELISA Kit is now available!
| Sensitivity : | 12.5 pg/mL |
| Assay Range : | 25.6 - 1,000 pg/mL |
| Applications : | ELISA |
Catalog #:
B004-5
BA
A New rm IL-18 is Now Available! Competitively priced; Enhanced stability; Lower endotoxin specification; Made in-house!
BA
| Source : | E. coli |
| Accession # : | AAK13416 |
| Applications : | Bioactivity |
Catalog #:
DY10320
ELISA
| Assay Range : | 6.25 - 400 pg/mL |
| Applications : | ELISA |
Catalog #:
IC646G
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #74801 |
| Applications : | Flow Cytometry |
Catalog #:
B003-5
BA
A New rh IL-18 is Available! Competitively priced; Higher purity; Lower endotoxin specifications; Made in-house!
Catalog #:
D048-6
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #93-10C |
| Applications : | ELISA Detection |
Catalog #:
AF588
WB, ICC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
