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340 results for "IGFBP-3" in Products
IGFBP-3 Products
IGFBP-3 (Insulin-like growth factor binding protein-3) modulates the biological activity of IGF. It circulates in a ternary complex with IGF and the acid-labile subunit (ALS). Proteolysis of IGFBP-3 by tissue plasminogen activator (tPA), a disintegrin and metalloproteases (ADAMs), and prostate specific antigen (PSA) contributes to IGFBP-3 degradation or a reduction in its affinity for IGF. The majority of soluble IGFBP-3 found in circulation is secreted from hepatic non-parenchymal cells. IGFBP-3 potentiates EGF-EGFR-mediated cell growth, modulates adipogenesis, and regulates TGF-beta signaling, DNA damage, apoptosis, autophagy, and gene transcription.
Reactivity:
Human
Assay Range:
0.781-50 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
78.1-5000 pg/mL (Cell Culture Supernates, EDTA Plasma)
Applications:
ELISA
Reactivity:
Mouse
Source:
NS0
Accession #:
CAA57271.1
Applications:
Bioactivity
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #84728
Applications:
IHC, WB, ELISA(Cap)
Reactivity:
Human
Source:
NS0
Accession #:
CAA46087
Applications:
Bioactivity
Reactivity:
Human
Assay Range:
125-8000 pg/mL
Applications:
ELISA
Reactivity:
Mouse
Details:
Rat IgG2B Monoclonal Clone #138202
Applications:
WB, ELISA(Cap)
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, Simple Western
Reactivity:
Mouse
Assay Range:
62.5-4000 pg/mL
Applications:
ELISA
Reactivity:
Rat
Assay Range:
31.25-2000 pg/mL
Applications:
ELISA
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA(Det)
Reactivity:
Human
Details:
Mouse IgG2 Monoclonal Clone #MM0342-6U23
Applications:
IHC, WB
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #1065833
Applications:
IHC, ICC/IF
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
![Immunohistochemistry-Frozen: IGFBP-3 Antibody [NBP2-16933]](https://resources.rndsystems.com/images/products/IGFBP-3-Antibody-Immunohistochemistry-Frozen-NBP2-16933-img0002.jpg "Immunohistochemistry-Frozen: IGFBP-3 Antibody [NBP2-16933]")
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA(Det)
Reactivity:
Human
Source:
Sf 9 (baculovirus)
Accession #:
P17936
Applications:
Bioactivity
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF
![Western Blot: IGFBP-3 Antibody [H00003486-D01P]](https://resources.rndsystems.com/images/products/IGFBP-3-Antibody-Western-Blot-H00003486-D01P-img0006.jpg "Western Blot: IGFBP-3 Antibody [H00003486-D01P]")
Chemical Name:
1-(3,4-Dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid
Purity:
≥98%
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #84728
Applications:
IHC, WB, ELISA(Cap), ELISA(Det)