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22 results for "GTPase Inhibitors Small Molecules and Peptides" in Products

GTPase Inhibitors Small Molecules and Peptides

Selective inhibitor of Rac1-GEF interaction; antioncogenic

Chemical Name:
N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
Purity:
≥98%
Selective inhibitor of Rac1-GEF interaction; antioncogenic

Potent Rac family inhibitor

Chemical Name:
5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride
Purity:
≥98%
Potent Rac family inhibitor

Non-competitive dynamin inhibitor

Chemical Name:
3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide
Purity:
≥98%
Non-competitive dynamin inhibitor

Selective Cdc42 Rho family inhibitor

Alternate Names:
CID 2950007
Chemical Name:
4-[4,5-Dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]benzenesulfonamide
Purity:
≥98%
Selective Cdc42 Rho family inhibitor

Dynamin I inhibitor

Chemical Name:
2-Cyano-3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-N-octyl-2-propenamide
Purity:
≥98%
Dynamin I inhibitor

DOCK2-Rac1 interaction inhibitor

Chemical Name:
4-[3-(2-Chlorophenyl)-2-propen-1-ylidene]-1-phenyl-3,5-pyrazolidinedione
Purity:
≥98%
DOCK2-Rac1 interaction inhibitor

Epac inhibitor

Chemical Name:
α-[(2-(3-Chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-3-isoxazolepropanenitrile
Purity:
≥98%
Epac inhibitor

Rho inhibitor

Chemical Name:
D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide hydrochloride
Purity:
≥98%
Rho inhibitor

Potent farnesyl diphosphate (FPP) synthase inhibitor

Alternate Names:
Zometa
Chemical Name:
[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Purity:
≥98%
Potent farnesyl diphosphate (FPP) synthase inhibitor

Gα-protein inhibitor; potent inhibitor of Gq/11 signaling

Chemical Name:
(R)-1-((3S,6S,9S,12S,18R,21S,22R)-21-acetamido-18-benzyl-3-((R)-1-methoxyethyl)-4,9,10,12,16,22-hexamethyl-15-methylene-2,5,8,11,14,17,20-heptaoxo-1,19-dioxa-4,7,10,13,16-pentaazacyclodocosan-6-yl)-2-methylpropyl (2S,3R)-2-acetamido-3-hydroxy-4-methylpentanoate
Purity:
≥95%
Gα-protein inhibitor; potent inhibitor of Gq/11 signaling

Selective ARF6 inhibitor

Chemical Name:
3-(4-Chlorophenyl)-5-(4-nitrophenyl)-2-(phenylmethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Purity:
≥98%
Selective ARF6 inhibitor

Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable

Purity:
≥95%
Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable

Potent covalent inhibitor of the RAS domain of the PI3K/p110α interaction

Chemical Name:
5-((1R,2S,5S)-2-(2-Chloro-3-fluorophenyl)-3-azabicyclo[3.1.0]hexan-3-yl)-N-((R,E)-4-(methylsulfonyl)but-3-en-2-yl)pyrazine-2-carboxamide
Purity:
≥98%
Potent covalent inhibitor of the RAS domain of the PI3K/p110α interaction

Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis

Chemical Name:
3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
Purity:
≥98%
Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis

Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis

Chemical Name:
3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
Purity:
≥98%
Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis

High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ

Chemical Name:
2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole trihydrochloride
Purity:
≥98%
High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ

Sec7-specific GEF inhibitor; selective for cytohesin family

Chemical Name:
N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide
Purity:
≥98%
Sec7-specific GEF inhibitor; selective for cytohesin family

Selective Epac2 inhibitor

Chemical Name:
2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole
Purity:
≥98%
Selective Epac2 inhibitor

Rac inhibitor

Chemical Name:
N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine
Purity:
≥98%
Rac inhibitor

Selective Epac2 inhibitor

Chemical Name:
2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole
Purity:
≥98%
Selective Epac2 inhibitor

Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Chemical Name:
[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone
Purity:
≥98%
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Chemical Name:
[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone
Purity:
≥98%
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
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