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59 results for "compounds-for-induced-pluripotent-stem-cells&view=expanded" in Products

Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component

GMP Version Available: TB1254-GMP
GMP
Alternate Names:
y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor
Chemical Name:
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity:
≥98%
ROCK inhibition by Y-27632 and immunostaining of skeletal myogenic differentiation of MESP1+ mesoderm,
(8)

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

GMP Version Available: TB1614-GMP
GMP
Chemical Name:
4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity:
≥99%
dopaminergic neurons derived from hiPSCs using SB 431542
(2)

Highly selective GSK-3 inhibitor; acts as Wnt activator

GMP Version Available: TB4423-GMP
GMP
Alternate Names:
CHIR99021,CT99021
Chemical Name:
6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity:
≥98%
Cardiomyocyte derived from human induced pluripotent stem cells (hiPSCs) using CHIR 99021.
(2)

SB 431542 synthesized to cGMP guidelines

Chemical Name:
4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity:
≥99%
SB 431542 synthesized to cGMP guidelines

EZH2 histone methyltransferase inhibitor

Alternate Names:
DZNep,NSC 617989,HY-12186
Chemical Name:
(1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride
Purity:
≥98%
EZH2 histone methyltransferase inhibitor

CHIR 99021 synthesized to cGMP guidelines

Chemical Name:
6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity:
≥99%
CHIR 99021 synthesized to cGMP guidelines
(2)

Adenylyl cyclase activator

Alternate Names:
Coleonol,Colforsin
Chemical Name:
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity:
≥98%
Adult Stem Cell-derived Liver Organoids
(2)

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names:
Compound C,BML-275
Chemical Name:
6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity:
≥98%
Potent AMPK inhibitor; also BMP type I receptor inhibitor

PORCN inhibitor; inhibits Wnt processing and secretion

Chemical Name:
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity:
≥98%
iPSC-derived heart organoids differentiated with IWP 2 and CHIR 99021
(2)

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name:
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity:
≥98%
Adult Stem Cell-derived Liver Organoids
(6)
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