8 results for "Akt2 Small Molecules and Peptides" in Products
Akt2: Small Molecules and Peptides
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
Potent and selective allosteric Akt1, Akt2 and Akt3 inhibitor
| Chemical Name: | 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
| Alternate Names: | Triciribine,NSC 154020,TCN |
| Chemical Name: | 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine |
| Purity: | ≥98% (HPLC) |
Potent and selective dual Akt1 and 2 inhibitor
| Alternate Names: | Akt Inhibitor VIII |
| Chemical Name: | 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Purity: | ≥98% (HPLC) |
Potent pan-Akt and PKA inhibitor
| Chemical Name: | 4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine hydrochloride |
| Purity: | ≥98% (HPLC) |
Akt activator
| Chemical Name: | 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester |
Akt kinase inhibitor. Antitumor
| Chemical Name: | 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol |
| Purity: | ≥98% (HPLC) |
Selective Akt/PKB inhibitor
| Alternate Names: | Akt Inhibitor X |
| Chemical Name: | 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent pan-AKT inhibitor
| Alternate Names: | Capivasertib |
| Chemical Name: | 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinecarboxamide |
| Purity: | ≥98% (HPLC) |
