11 results for "Adrenergic Transporter Inhibitors" in Products
Adrenergic Transporter Inhibitors Products
Adrenergic transporters (NET) are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) widely distributed throughout the brain within noradrenergic neuronal plasma membranes. They are responsible for the re-uptake of adrenalin, noradrenalin and (to a lesser extent) dopamine from the synaptic cleft back into vesicles for storage until later use, resulting in the termination of neurotransmitter action.
Adrenergic transporters contain the following structural motifs: 12-TM domains, extracellular loops, cytoplasmic C- and N-termini and putative phosphorylation sites. A role for NETs has been proposed in attention deficit disorder, substance abuse, neurodegenerative disorders and clinical depression.
Selective inhibitor of noradrenalin transporters
| Chemical Name: | 10-11-Dihydro-N-methyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Non-selective inhibitor of dopamine and noradrenalin transporters
| Chemical Name: | 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent inhibitor of vesicular monoamine transport
| Chemical Name: | (3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one |
| Purity: | ≥98% (HPLC) |
Potent and selective noradrenalin re-uptake inhibitor
| Alternate Names: | Atomoxetine,LY 139603 |
| Chemical Name: | (R)-N-Methyl-γ-(2-methylphenoxy)-benzenepropanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Noradrenalin re-uptake inhibitor
| Chemical Name: | (±)-γ-(2-Methoxyphenoxy)-N-methylbenzenepropanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent noradrenalin and dopamine uptake inhibitor. Antidepressant
| Chemical Name: | 1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate |
| Purity: | ≥98% (HPLC) |
Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment
| Chemical Name: | 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective noradrenalin uptake inhibitor; orally active
| Chemical Name: | (2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate |
| Purity: | ≥98% (HPLC) |
5-HT and NA reuptake inhibitor (SNRI)
| Alternate Names: | Wy 45030 |
| Chemical Name: | 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake
| Chemical Name: | (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake
| Alternate Names: | Lu 19-005 |
| Chemical Name: | (1R,3S)-rel-3-(3,4-Dichlorophenyl)-2,3-dihydro-N-methyl-1H-inden-1-amine hydrochloride |
| Purity: | ≥98% (HPLC) |
