Reboxetine mesylate

Tocris Bioscience, part of Bio-Techne | Catalog # 1982

Potent and selective noradrenalin uptake inhibitor; orally active
Catalog #
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1982/10
1982/50
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Key Product Details

Description

Potent and selective noradrenalin uptake inhibitor; orally active

View all Adrenergic Transporter Inhibitors »

Product Description

Reboxetine mesylate is a potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over α-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant.

Product Specifications

Molecular Weight

409.50

Formula

C19H23NO3.CH3SO3H

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate

CAS Number

98769-84-7

PubChem ID

76970698

InChI Key

OEQQXKDUXVTKMH-BGLVZNNJSA-N

SMILES

[H][C@]2(OCCNC2)[C@@H]([C@]3=CC=CC=C3)OC1=C(OCC)C=CC=C1.[H][C@@]5(OCCNC5)[C@H]([C@]6=CC=CC=C6)OC4=C(OCC)C=CC=C4.CS(=O)(O)=O.CS(=O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 20.48 50
DMSO 20.48 50

Preparing Stock Solutions for Reboxetine mesylate

The following data is based on the product molecular weight 409.50

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.88 mL 24.42 mL 48.84 mL
2.5 mM 0.98 mL 4.88 mL 9.77 mL
5 mM 0.49 mL 2.44 mL 4.88 mL
25 mM 0.10 mL 0.49 mL 0.98 mL

Calculators

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Product Documents for Reboxetine mesylate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Reboxetine mesylate

For research use only

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