751 results for "TIM-3" in Products
TIM-3 Products
TIM-3 (T cell immunoglobulin and mucin domain-3), also known as HAVCR2 is an immunosuppressive protein that enhances tolerance and inhibits anti-tumor immunity. It is upregulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). TIM-3 ligation by Galectin-9 attenuates CD8+ and Th1 cell responses and promotes the activity of Treg and myeloid derived suppressor cells. Dendritic cell-expressed TIM-3 dampens inflammation by enabling the phagocytosis of apoptotic cells and the cross-presentation of apoptotic cell antigens. TIM-3 also binds the alarmin HMGB1, thereby preventing the activation of TLRs in response to released tumor cell DNA.
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
![Immunohistochemistry-Paraffin: TIM-3 Antibody (TIM3/3113) - Azide and BSA Free [NBP2-79836]](https://resources.bio-techne.com/images/products/TIM-3-Antibody-TIM3-3113-Azide-and-BSA-Free-Immunohistochemistry-Paraffin-NBP2-79836-img0003.jpg "Immunohistochemistry-Paraffin: TIM-3 Antibody (TIM3/3113) - Azide and BSA Free [NBP2-79836]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
![Immunohistochemistry-Paraffin: TIM-3 Antibody (TIM3/3113) [NBP2-79702]](https://resources.bio-techne.com/images/products/TIM-3-Antibody-TIM3-3113-Immunohistochemistry-Paraffin-NBP2-79702-img0003.jpg "Immunohistochemistry-Paraffin: TIM-3 Antibody (TIM3/3113) [NBP2-79702]")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113 |
| Applications: | IHC, ELISA, Endotoxin |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIM3/6863R |
| Applications: | IHC |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Applications: | Simple Plex |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
