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Synthase/Synthetase Inhibitors: Small Molecules and Peptides

A type of ligase enzyme within the E.C. 6 class, synthases/synthetases are involved in synthetic reactions. They also catalyze the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

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8 results for "Synthase/Synthetase Inhibitors Small Molecules and Peptides" in Products

8 results for "Synthase/Synthetase Inhibitors Small Molecules and Peptides" in Products

Synthase/Synthetase Inhibitors: Small Molecules and Peptides

A type of ligase enzyme within the E.C. 6 class, synthases/synthetases are involved in synthetic reactions. They also catalyze the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

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Inhibitor of acyl-CoA synthetase

Chemical Name: (2E,4E,7E)-2,4,7-Undecatrienal nitrosohydrazone
Purity: ≥95% (HPLC)
Inhibitor of acyl-CoA synthetase

High affinity competitive prolyl-tRNA synthetase inhibitor

Chemical Name: (2R*,3S*)-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4-3H-quinazolinone hydrobromide
Purity: ≥98% (HPLC)
High affinity competitive prolyl-tRNA synthetase inhibitor

ATP synthase inhibitor; proapoptotic

Chemical Name: 7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one
Purity: ≥98% (HPLC)
ATP synthase inhibitor; proapoptotic

Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

Chemical Name: N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide
Purity: ≥98% (HPLC)
Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

Irreversible γ-glutamylcysteine synthetase (γ-GCS) inhibitor; induces ferroptosis

Chemical Name: (2S)-2-Amino-4-(S-butylsulfonimidoyl)butanoic acid
Purity: ≥98% (HPLC)
Irreversible γ-glutamylcysteine synthetase (γ-GCS) inhibitor; induces ferroptosis

Potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS)

Alternate Names: RU320521
Chemical Name: 3-[1-(6,7-Dichloro-1H-benzimidazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-1(3H)-isobenzofuranone
Purity: ≥98% (HPLC)
Potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS)

Human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

Chemical Name: 4-(Diphenylmethoxy)-1-(3-2H-tetrazol-5-yl)propyl]-piperidine
Purity: ≥98% (HPLC)
Human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

Pancreatic, gastric and carboxylester lipase inhibitor; antiobesity and antihypercholesterolemic activity

Chemical Name: N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester
Purity: ≥98% (HPLC)
Pancreatic, gastric and carboxylester lipase inhibitor; antiobesity and antihypercholesterolemic activity
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