Triacsin C
Tocris Bioscience, part of Bio-Techne | Catalog # 2472
Inhibitor of acyl-CoA synthetase
Key Product Details
Description
Inhibitor of acyl-CoA synthetase
Product Description
Triacsin C is an inhibitor of acyl-CoA synthetase. Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft tumor growth in mice.Product Specifications
Molecular Weight
207.27
Formula
C11H17N3O
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(2E,4E,7E)-2,4,7-Undecatrienal nitrosohydrazone
CAS Number
76896-80-5
PubChem ID
9576787
InChI Key
NKTGCVUIESDXPU-YLEPRARLSA-N
SMILES
O=NN/N=C/C=C/C=C/C/C=C/CCC
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 5 |
Preparing Stock Solutions
for Triacsin C
The following data is based on the product molecular weight 207.27
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 19.30 mL | 96.49 mL | 192.98 mL |
| 1.25 mM | 3.86 mL | 19.30 mL | 38.60 mL |
| 2.5 mM | 1.93 mL | 9.65 mL | 19.30 mL |
| 12.5 mM | 0.39 mL | 1.93 mL | 3.86 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Mashima p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target. J.Natl.Cancer.Inst. 2005 PMID: 15900046
- Tomoda Evidence for an essential role of long chain acyl-CoA synthetase in animal cell proliferation. Inhibition of long chain acyl-CoA synthetase by triacsins caused inhibition of Raji cell proliferation. J.Biol.Chem. 1991 PMID: 1999415
Product Specific Notices for Triacsin C
For research use only
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