12 results for "Protein Kinase C Inhibitors" in Products
Protein Kinase C Inhibitors Products
Protein kinase C (PKC) refers to a family of serine/threonine protein kinases grouped by their activation mechanism. Classical or conventional PKCs (cPKC α-, βI- , βII- and γ-) are activated by phosphatidylserine in a calcium dependent manner and can bind diacylglycerol (DAG). The Ca2+ insensitive novel PKCs (nPKCs ε-, δ-, θ- and η- isotypes) are also activated by DAG and phosphatidylserine.
The atypical PKCs (aPKCs ι- and ζ-) are insensitive to ...
Protein kinase C inhibitor
| Alternate Names: | Gö 6850,Bisindolylmaleimide I |
| Chemical Name: | 2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide |
| Purity: | ≥98% (HPLC) |
Potent protein kinase C inhibitor; selective for α and β isozymes
| Chemical Name: | 5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile |
| Purity: | ≥95% (HPLC) |
Cell-permeable protein kinase C inhibitor
| Chemical Name: | 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride |
| Purity: | ≥98% (HPLC) |
Potent, selective and photo-dependent PKC inhibitor
| Alternate Names: | UCN 1028C,PKF 115584 |
| Chemical Name: | (1R)-2-[12-[(2R)-2-(Benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethylcarbonic acid 4-hydroxyphenyl ester |
| Purity: | ≥95% (HPLC) |
Inhibits Gs and stimulates Gi activity
| Purity: | ≥95% (HPLC) |
Cell-permeable inhibitor of atypical PKC isozyme PKMζ
| Alternate Names: | z-Pseudosubstrate inhibitory peptide |
| Purity: | ≥95% (HPLC) |
Broad spectrum PKC inhibitor
| Alternate Names: | Goe 6983 |
| Chemical Name: | 3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Purity: | ≥98% (HPLC) |
Reported PKCδ inhibitor
| Chemical Name: | 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone |
| Purity: | ≥95% (HPLC) |
PKCι and PKCζ inhibitor
| Chemical Name: | (2S)-3-Phenyl-N1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine dihydrochloride |
| Purity: | ≥95% (HPLC) |
Selective inhibitor of PKCβII
| Chemical Name: | 5,6-bis[(4-Fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione |
| Purity: | ≥98% (HPLC) |
Potent, orally active PKC inhibitor
| Chemical Name: | 3-[(8S)-8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione hydrochloride |
| Purity: | ≥98% (HPLC) |
Staurosporine synthesized to Ancillary Material Grade
| Chemical Name: | [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one |
| Purity: | ≥98% |
