PP2A: Small Molecules and Peptides
Protein Phosphatase 2A (PP2A) is an enzyme that removes phosphates covalently attached to serine and threonine residues in proteins. It contains three subunits; a catalytic subunit C (PP2Ac), an assembly/structural subunit A (PP2Aa), and a regulatory subunit B (PP2Ab). PP2A is a ubiquitous enzyme that plays a role in regulating many cellular activities varying from ion transport in erythrocytes to suppressing tumor growth. Binding of the SV40 small T antigen to the PP2A phosphatase complex is known to cause oncogenic transformation.
5 results for "PP2A Small Molecules and Peptides" in Products
5 results for "PP2A Small Molecules and Peptides" in Products
PP2A: Small Molecules and Peptides
Protein Phosphatase 2A (PP2A) is an enzyme that removes phosphates covalently attached to serine and threonine residues in proteins. It contains three subunits; a catalytic subunit C (PP2Ac), an assembly/structural subunit A (PP2Aa), and a regulatory subunit B (PP2Ab). PP2A is a ubiquitous enzyme that plays a role in regulating many cellular activities varying from ion transport in erythrocytes to suppressing tumor growth. Binding of the SV40 small T antigen to the PP2A phosphatase complex is known to cause oncogenic transformation.
Substrate for Calcineurin, PP1, PP2A, PP2C, and Ser/Thr phosphatases
Protein phosphatase 1 and 2A inhibitor
| Chemical Name: | 9,10-Deepithio-9,10-didehydroacanthifolicin |
| Purity: | ≥90% (HPLC) |
Protein phosphatase 1 and 2A inhibitor
| Chemical Name: | N-[(3S)-[4-(1E)-3-[(2R,3R,4R,7S,8S,9R)-2-[(1S,3S,4S,5R,7E,9E,11E,13Z)-14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraenyl]-9-hydroxy-4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-propenyl]-2-oxazoly]butyl]-4-deoxy-4-(dimethylamino)-5-O-methyl-L-ribonamide |
| Purity: | ≥90% (HPLC) |
YAP inhibitor
| Purity: | ≥95% (HPLC) |
Potent, selective and irreversible protein phosphatase methylesterase-1 (PME-1) inhibitor
| Chemical Name: | (2E)-2-[(4-Fluorophenyl)sulfonyl]-3-[1-[(3-nitrophenyl)sulfonyl]-1H-pyrrol-2-yl]-2-propenenitrile |
| Purity: | ≥98% (HPLC) |
