6 results for "Nrf2 Activators Small Molecules and Peptides" in Products
Nrf2 Activators: Small Molecules and Peptides
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2, also known as NFE2L2) is a member of the basic leucine zipper family of transcription factors. Under normal physiological conditions, Nrf2 has a short half-life of around 20 minutes and is retained in the cytoplasm before being degraded by the concerted actions of Kelch-like ECH-associated protein 1 (Keap1) and Cullin 3. Cullin 3, a ubiquitin E3 ligase ubiquitinates Nrf2, targeting it for proteasomal degradation, in a process facilitated by the ...
Nrf2 activator; cell permeable
| Chemical Name: | 2-Methylenebutanedioic acid 4-octyl ester |
| Purity: | ≥98% (HPLC) |
Nrf2 activator; inhibits Nrf2/Keap1 interaction
| Chemical Name: | (3S)-1-[4-[[(2,3,5,6-Tetramethylphenyl)sulfonyl]amino]-1-naphthalenyl]-3-pyrrolidinecarboxylic acid |
| Purity: | ≥98% (HPLC) |
Nrf2 signaling activator
| Chemical Name: | 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole |
| Purity: | ≥98% (HPLC) |
PGK1 inhibitor; activates Nrf2
| Chemical Name: | (3R,4S)-rel-4-[(4-Chlorophenyl)sulfonyl]tetrahydro-N-(2-methylpropyl)-3-thiophenamine-1,1-dioxide |
| Purity: | ≥98% (HPLC) |
Nrf2 activator
| Chemical Name: | N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea |
| Purity: | ≥98% (HPLC) |
Caspase-1 and NLRP3 inflammasome inhibitor
| Chemical Name: | Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate |
| Purity: | ≥98% (HPLC) |
