CDDO Im

Tocris Bioscience, part of Bio-Techne | Catalog # 4737

Nrf2 signaling activator
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Key Product Details

Description

Nrf2 signaling activator

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Product Description

CDDO Im is an Nrf2 signaling activator; increases Nrf2 protein expression and enhances Nrf2-dependent cytoprotective gene expression. CDDO Im inhibits cell growth and induces apoptosis of pancreatic cancer cells in vitro. Also reduces acetaminophen-induced liver injury in mice.

Product Specifications

Molecular Weight

541.72

Formula

C34H43N3O3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole

CAS Number

443104-02-7

PubChem ID

9958995

InChI Key

ITFBYYCNYVFPKD-FMIDTUQUSA-N

SMILES

O=C1C(C#N)=C[C@@]2(C)[C@](CC[C@]([C@@]4(C)[C@]([H])3[C@@]5([H])[C@@](CCC(C)(C)C5)([C@](N6C=NC=C6)=O)CC4)(C)C2=CC3=O)([H])C(C)1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 54.17 100

Preparing Stock Solutions for CDDO Im

The following data is based on the product molecular weight 541.72

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.85 mL 9.23 mL 18.46 mL
5 mM 0.37 mL 1.85 mL 3.69 mL
10 mM 0.18 mL 0.92 mL 1.85 mL
50 mM 0.04 mL 0.18 mL 0.37 mL

Calculators

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Reconstitution Calculator

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Product Documents for CDDO Im

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CDDO Im

For research use only

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