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MMP-13 Products

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

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189 results for "MMP-13" in Products

189 results for "MMP-13" in Products

MMP-13 Products

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

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Applications: ELISA
Human Total MMP-13 ELISA Standard Curve
Sensitivity: 21.3 pg/mL
Applications: ELISA
Assay Range: 78 - 5,000 pg/mL (Cell Culture Supernates)
Human Pro-MMP-13 ELISA Standard Curve
(2)
Source: NS0
Accession #: P45452
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human, Mouse, Rat
Details: Mouse IgG2A Monoclonal Clone #OTI2D8
Applications: IHC, WB, ICC/IF, Mycoplasma
Western Blot: MMP-13 Antibody (OTI2D8) [NBP2-45887]
(9)

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Applications: NULL
Human MMP Luminex Assay Standard Curves
(2)

Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Immunohistochemistry-Paraffin: MMP-13 Antibody [NBP2-17310]
(3)
Reactivity: Human, Mouse, Rat
Details: Mouse IgG2A Monoclonal Clone #OTI2D8
Applications: IHC, WB, ICC/IF, Mycoplasma
Western Blot: MMP-13 Antibody (OTI2D8)Azide and BSA Free [NBP2-72740]
(9)

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse
Details: Rabbit IgG Monoclonal Clone #JF0893
Applications: IHC, WB, ICC/IF, Flow
Western Blot: MMP-13 Antibody (JF0893) [NBP2-66954]
(8)

Selective inhibitor of MMP-13

Chemical Name: N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride
Purity: ≥98% (HPLC)
Selective inhibitor of MMP-13

Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors

Potent MMP inhibitor

Alternate Names: SC 78080
Chemical Name: N-Hydroxy-1-(2-methoxyethyl)-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl]-4-piperidinecarboxamide hydrochloride
Purity: ≥98% (HPLC)
Potent MMP inhibitor
Applications: ELISA
ELISA: Rat MMP-13 ELISA Kit (Colorimetric) [NBP3-06931]
(4)
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