Histamine H3 R: Small Molecules and Peptides
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors Histamine H1 R, Histamine H2 R, Histamine H3 R and Histamine H4 R. HRH3 encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. Histamine H3 R is an integral membrane protein and can regulate neurotransmitter release. It can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
10 results for "Histamine H3 R Small Molecules and Peptides" in Products
10 results for "Histamine H3 R Small Molecules and Peptides" in Products
Histamine H3 R: Small Molecules and Peptides
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors Histamine H1 R, Histamine H2 R, Histamine H3 R and Histamine H4 R. HRH3 encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. Histamine H3 R is an integral membrane protein and can regulate neurotransmitter release. It can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
Endogenous histamine receptor agonist
| Chemical Name: | 2-(4-Imidazolyl)ethylamine dihydrochloride |
Potent, standard H3 agonist
| Chemical Name: | (R)-(-)-α-Methyl-1H-imidazole-4-ethanamine dihydrobromide |
| Purity: | ≥98% (HPLC) |
H3 antagonist; also H4 inverse agonist
| Chemical Name: | N-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide |
| Purity: | ≥98% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
Standard H3 agonist. Also H4 agonist
| Chemical Name: | 4-(1H-Imidazol-4-ylmethyl)piperidine dihydrobromide |
Highly potent H3 antagonist and H4 partial agonist
| Alternate Names: | VUF 9153 |
| Chemical Name: | N-(4-Chlorobenzyl)-S-[3-(4(5)-imidazolyl)propyl]isothiourea dihydrobromide |
| Purity: | ≥98% (HPLC) |
Standard H3 and H4 agonist (H3 > H4)
| Chemical Name: | 5-[2-(Imidazol-4-yl)ethyl]isothiourea dihydrobromide |
| Purity: | ≥98% (HPLC) |
High affinity H3 antagonist
| Chemical Name: | 1-[3-[4-(1-Piperidinylmethyl)phenoxy]propyl]piperidine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective H3 inverse agonist
| Chemical Name: | 1-[3-[3-(4-Chlorophenyl)propoxy]propyl]-piperidine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥98% (HPLC) |
