Immepip dihydrobromide
Tocris Bioscience, part of Bio-Techne | Catalog # 0932
Standard H3 agonist. Also H4 agonist
Key Product Details
Description
Standard H3 agonist. Also H4 agonist
Product Description
Immepip dihydrobromide is a potent histamine H3 receptor agonist. Also binds to H4 receptors (Ki values are 0.4 and 9 nM at human recombinant H3 and H4 receptors respectively). Equipotent to or slightly more active than (R)-α-methylhistamine at H3 receptors.Product Specifications
Molecular Weight
327.06
Formula
C9H15N3.2HBr
Storage
Desiccate at RT
Chemical Name
4-(1H-Imidazol-4-ylmethyl)piperidine dihydrobromide
CAS Number
164391-47-3
PubChem ID
22315065
InChI Key
YGNJPNRDGXJQJX-UHFFFAOYSA-N
SMILES
Br.Br.C(C1CCNCC1)C1=CNC=N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 32.71 | 100 |
Preparing Stock Solutions
for Immepip dihydrobromide
The following data is based on the product molecular weight 327.06
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.06 mL | 15.29 mL | 30.58 mL |
| 5 mM | 0.61 mL | 3.06 mL | 6.12 mL |
| 10 mM | 0.31 mL | 1.53 mL | 3.06 mL |
| 50 mM | 0.06 mL | 0.31 mL | 0.61 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Liu Cloning and pharmacological characterization of a fourth histamine receptor (H4) expressed in bone marrow. Mol. Pharmacol. 2001 PMID: 11179434
- Vollinga A new potent and selective histamine H3 receptor agonist. J.Med.Chem. 1994 PMID: 8308858
- Coruzzi Cardiovascular effects of selective agonists and antagonists of histamine H3 receptors in the anaesthetized rat. Naunyn Schmiedebergs Arch.Pharmacol. 1995 PMID: 7675114
Product Specific Notices for Immepip dihydrobromide
For research use only
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