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6 results for "Guanylyl Cyclase Activators Small Molecules and Peptides" in Products

Guanylyl Cyclase Activators: Small Molecules and Peptides

Guanylyl Cyclases (GC) are a group of enzymes that, in the presence of a metal ion co-factor such as Mg2+ or Mn2+, convert guanosine-5'-triphosphate (GTP) into 3',5'-guanosine monophosphate (cGMP) and pyrophosphate. The second messenger cGMP participates in signaling by stimulating protein kinase G enzymes, altering the conductance of cGMP-gated ion channels and changing the activity of cGMP-regulated phosphodiesterases.

There are two main groups of guanylyl cyclase; soluble GC ...

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Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest

Chemical Name: 3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole
Purity: ≥98% (HPLC)
Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest

Endogenous activator of intestinal guanylyl cyclase

Purity: ≥95% (HPLC)
Endogenous activator of intestinal guanylyl cyclase

Potent soluble guanylyl cyclase (sGC) activator

Alternate Names: Cinaciguat hydrochloride
Chemical Name: 4-[[(4-Carboxybutyl)[2-[2-[[4-(2-phenylethyl)phenyl]methoxy]phenyl]ethyl]amino]methyl]benzoic acid hydrochloride
Purity: ≥98% (HPLC)
Potent soluble guanylyl cyclase (sGC) activator

Soluble guanylyl cyclase (sGC) activator

Chemical Name: 5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine
Purity: ≥98% (HPLC)
Soluble guanylyl cyclase (sGC) activator

Guanylyl cyclase (sGC) stimulator

Chemical Name: 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine
Purity: ≥98% (HPLC)
Guanylyl cyclase (sGC) stimulator

Water-soluble NO donor

Alternate Names: 3-Morpholinylsydnoneimine chloride
Chemical Name: Amino-3-morpholinyl-1,2,3-oxadiazolium chloride
Purity: ≥98% (HPLC)
Water-soluble NO donor
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