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9 results for "ERK Inhibitors" in Products

ERK Inhibitors Products

Potent and selective ERK2 inhibitor

Alternate Names: VX 11e
Chemical Name: 4-[2-[(2-Chloro-4-fluorophenyl)amino]-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide
Purity: ≥98% (HPLC)
Potent and selective ERK2 inhibitor

Selective ERK inhibitor

Chemical Name: 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine
Purity: ≥98% (HPLC)
Selective ERK inhibitor

ERK5/BMK1 inhibitor; also BRD4 inhibitor

Chemical Name: 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
Purity: ≥98% (HPLC)
ERK5/BMK1 inhibitor; also BRD4 inhibitor

Potent and selective ERK5 inhibitor

Chemical Name: 5,11-Dihydro-2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5-methyl,11-(methylsulfonyl)-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
Purity: ≥98% (HPLC)
Potent and selective ERK5 inhibitor

Selective MEK5 and ERK5 inhibitor

Chemical Name: (3Z)-3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide
Purity: ≥98% (HPLC)
Selective MEK5 and ERK5 inhibitor

Potent and selective KRASG12C inhibitor

Alternate Names: Sotorasib
Chemical Name: (1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one
Purity: ≥98% (HPLC)
Potent and selective KRASG12C inhibitor

Potent and selective PERK inhibitor; orally bioavailable

Chemical Name: 4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride
Purity: ≥98% (HPLC)
Potent and selective PERK inhibitor; orally bioavailable

Naturally occuring flavonoid and antioxidant; neuroprotective

Chemical Name: 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
Purity: ≥97% (HPLC)
Naturally occuring flavonoid and antioxidant; neuroprotective

Selective LPA2 receptor non-lipid agonist

Chemical Name: 2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]benzoic acid
Purity: ≥98% (HPLC)
Selective LPA2 receptor non-lipid agonist
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