11 results for "Akt Small Molecules and Peptides" in Products
Akt Small Molecules and Peptides
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
Akt kinase inhibitor. Antitumor
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
Selective Akt/PKB inhibitor
Akt activator
PKB/Akt inhibitor; also modulates Kv2.1 current
Potent and selective dual Akt1 and 2 inhibitor
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
Potent pan-Akt and PKA inhibitor
SPOP E3 ubiquitin ligase inhibitor
SPOP E3 ubiquitin ligase inhibitor