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13 results for "TOR Small Molecules and Peptides" in Products

TOR Small Molecules and Peptides

The mammalian Target of Rapamycin (mTOR) is a member of the PI 3-kinase-related kinase (PIKK) family. mTOR is the protein target of rapamycin, an anti-rejection drug used in transplantation and is a promising anti-cancer agent. mTOR plays a crucial role in the control of cell growth and proliferation as a downstream target of the PI 3-kinase/Akt signal transduction pathway.

Potent and selective mTOR inhibitor

Chemical Name:
1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one
Purity:
≥98%
Potent and selective mTOR inhibitor

mTOR inhibitor; immunosuppressant

Chemical Name:
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
Purity:
≥98%
mTOR inhibitor; immunosuppressant

Selective mTOR inhibitor

Chemical Name:
rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
Purity:
≥97%
Selective mTOR inhibitor

mTOR inhibitor; Immunosuppressant

Alternate Names:
RAD001
Chemical Name:
42-O-(2-Hydroxyethyl)rapamycin
Purity:
≥98%
mTOR inhibitor; Immunosuppressant

Inhibitor of PI 3-kinase, mTOR and DNA-PK

Chemical Name:
3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride
Purity:
≥97%
Inhibitor of PI 3-kinase, mTOR and DNA-PK

Potent and selective mTOR inhibitor

Chemical Name:
9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-benzo[h]-1,6-naphthyridin-2(1H)-one
Purity:
≥98%
Potent and selective mTOR inhibitor

Dual mTORC1/mTORC2 inhibitor

Chemical Name:
2-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol
Purity:
≥98%
Dual mTORC1/mTORC2 inhibitor

PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro

Chemical Name:
3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one
Purity:
≥98%
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro

Naturally occuring flavonoid and antioxidant; neuroprotective

Chemical Name:
2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
Purity:
≥97%
Naturally occuring flavonoid and antioxidant; neuroprotective

mTOR inhibitor; antitumor

Alternate Names:
CCI-779
Chemical Name:
Rapamycin 42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate]
Purity:
≥98%
mTOR inhibitor; antitumor

Potent and selective mTOR inhibitor

Chemical Name:
N-[4-[4-(4-Morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-carbamic acid methyl ester dihydrochloride
Purity:
≥98%
Potent and selective mTOR inhibitor

Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK

Alternate Names:
GSK2126458
Chemical Name:
2,4-Difluoro-N-[2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide
Purity:
≥98%
Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK

Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK

Alternate Names:
GSK2126458
Chemical Name:
2,4-Difluoro-N-[2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide
Purity:
≥98%
Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK
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