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438 results for "Tie-2" in Products

Tie-2 Products

Tie-2, also known as Tek, is a transmembrane receptor tyrosine kinase (RTK) that functions as a receptor for Angiopoietin family proteins. It is expressed by embryonic and adult endothelial cells, hematopoietic stem cells, and a circulating population of proangiogenic monocytes. Tie-2 signaling is activated by Angiopoietins-1 and -4, while it can be either activated or inhibited by Angiopoietins-2 and -3. Tie-2 plays an important role in maintaining vascular integrity by mediating endothelial ...

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Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.

Applications: Simple Plex
Custom Simple Plex Assay Panel

Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies

Detection of Human Receptor Tyrosine Kinase Phosphorylation in KATO-III Cell Line.
(2)

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

R&D Systems Proteome Profiler Antibody Array Kits

Potent Tie2 inhibitor

Chemical Name: [3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluorosulfur
Purity: ≥98% (HPLC)
Potent Tie2 inhibitor

Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies

The Mouse Phospho-RTK Array detects multiple tyrosine phosphorylated receptors in untreated and ligand-treated cell lysates.

Simple Plex Human Tie-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer. Sample type indicated with PS (Plasma/Serum).

Applications: Simple Plex
Human Tie-2 Ella Assay
(3)

Control for use with Human Tie-2 Simple Plex Cartridge Kit

Applications: Ctrl, Simple Plex
R&D Systems VersaClone cDNA Plasmids
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: WB, IHC, CyTOF-ready, ICFlow
Detection of Mouse Phospho-Tie-2 (Y992) antibody by Western Blot.
(4)

Potent VEGFR inhibitor; also inhibits other RTKs

Alternate Names: Cabozantinib,BMS 907351
Chemical Name: N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
Purity: ≥98% (HPLC)
Potent VEGFR inhibitor; also inhibits other RTKs
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #83715
Applications: Flow
Detection of Tie-2 antibody in HUVEC Human Cells antibody by Flow Cytometry.
(3)
Reactivity: Mouse, Rat
Details: Goat IgG Polyclonal
Source: NS0
Accession #: Q02763
Applications: BA
Recombinant Human Tie-2 Fc Chimera Protein Binding Activity
Assay Range: 156 - 10,000 pg/mL
Applications: ELISA
Human Tie-2 ELISA Standard Curve
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