TfR (Transferrin R) Products
Transferrin Receptor (TfR, TfR-1, CD71) is a transmembrane glycoprotein expressed on erythroid progenitors, muscle cells and proliferating cells as a disulfide-linked homodimer. As the major mediator of cellular iron uptake, it binds and internalizes diferric transferrin, allowing iron release at the low pH of the endosome. Proteolytic shedding of TfR into the circulation is enhanced by iron deficiency. The hereditary hemochromatosis protein HFE competes with diferric transferrin for binding to TfR and targets TfR for degradation rather than recycling. Cancer cells can express up to 5-fold more TfR than quiescent cells in the surrounding tissue. TfR carries out ferritin-independent functions in T cell development, immunological synapse formation and Galectin-3-mediated cell death, and it serves as a cell entry receptor for New World hemorrhagic fever arenaviruses.
720 results for "TfR (Transferrin R)" in Products
720 results for "TfR (Transferrin R)" in Products
TfR (Transferrin R) Products
Transferrin Receptor (TfR, TfR-1, CD71) is a transmembrane glycoprotein expressed on erythroid progenitors, muscle cells and proliferating cells as a disulfide-linked homodimer. As the major mediator of cellular iron uptake, it binds and internalizes diferric transferrin, allowing iron release at the low pH of the endosome. Proteolytic shedding of TfR into the circulation is enhanced by iron deficiency. The hereditary hemochromatosis protein HFE competes with diferric transferrin for binding to TfR and targets TfR for degradation rather than recycling. Cancer cells can express up to 5-fold more TfR than quiescent cells in the surrounding tissue. TfR carries out ferritin-independent functions in T cell development, immunological synapse formation and Galectin-3-mediated cell death, and it serves as a cell entry receptor for New World hemorrhagic fever arenaviruses.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29806 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func, B/N |
![Western Blot: TfR (Transferrin R) AntibodyBSA Free [NB100-92243]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-Western-Blot-NB100-92243-img0006.jpg "Western Blot: TfR (Transferrin R) AntibodyBSA Free [NB100-92243]")
| Reactivity: | Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OX26 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
![Western Blot: TfR (Transferrin R) Antibody (OX26)BSA Free [NB200-585]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-OX26-Western-Blot-NB200-585-img0009.jpg "Western Blot: TfR (Transferrin R) Antibody (OX26)BSA Free [NB200-585]")
| Source: | CHO |
| Accession #: | Q62351 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #8D3 |
| Applications: | IHC, ICC/IF, Flow, CyTOF-ready, Func |
![Immunocytochemistry/ Immunofluorescence: TfR (Transferrin R) Antibody (8D3) - Azide Free [NB100-64979]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-8D3-Immunocytochemistry-Immunofluorescence-NB100-64979-img0002.jpg "Immunocytochemistry/ Immunofluorescence: TfR (Transferrin R) Antibody (8D3) - Azide Free [NB100-64979]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #DF1513 |
| Applications: | WB, ICC/IF, Flow, Simple Western |
![Western Blot: TfR (Transferrin R) Antibody (DF1513) [NBP2-32945]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-DF1513-Western-Blot-NBP2-32945-img0006.jpg "Western Blot: TfR (Transferrin R) Antibody (DF1513) [NBP2-32945]")
| Reactivity: | Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OX26 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
![Western Blot: TfR (Transferrin R) Antibody (OX26)Azide and BSA Free [NBP2-80976]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-OX26-Azide-and-BSA-Free-Western-Blot-NBP2-80976-img0001.jpg "Western Blot: TfR (Transferrin R) Antibody (OX26)Azide and BSA Free [NBP2-80976]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: TfR (Transferrin R) Antibody [NBP1-85741]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-Immunohistochemistry-Paraffin-NBP1-85741-img0015.jpg "Immunohistochemistry-Paraffin: TfR (Transferrin R) Antibody [NBP1-85741]")
| Applications: | AC |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29806 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat, Monkey, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #1A1B2 |
| Applications: | WB, ELISA |
![Western Blot: TfR (Transferrin R) Antibody (1A1B2)BSA Free [NBP2-37317]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-1A1B2-Western-Blot-NBP2-37317-img0004.jpg "Western Blot: TfR (Transferrin R) Antibody (1A1B2)BSA Free [NBP2-37317]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #DF1513 |
| Applications: | WB, ICC/IF, Flow, CyTOF-ready, Simple Western |
![Western Blot: TfR (Transferrin R) Antibody (DF1513)Azide and BSA Free [NBP2-34602]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-DF1513-Azide-and-BSA-Free-Western-Blot-NBP2-34602-img0007.jpg "Western Blot: TfR (Transferrin R) Antibody (DF1513)Azide and BSA Free [NBP2-34602]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #TFRC/1817 |
| Applications: | IHC, WB, ELISA, CyTOF-ready |
![Immunohistochemistry-Paraffin: TfR (Transferrin R) Antibody (TFRC/1817) - Azide and BSA Free [NBP2-54467]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-TFRC-1817-Azide-and-BSA-Free-Immunohistochemistry-Paraffin-NBP2-54467-img0003.jpg "Immunohistochemistry-Paraffin: TfR (Transferrin R) Antibody (TFRC/1817) - Azide and BSA Free [NBP2-54467]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29806 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29806 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29806 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29806 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29806 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #040 |
| Applications: | ICC/IF, Flow |
![Immunocytochemistry/ Immunofluorescence: TfR (Transferrin R) Antibody (040) [NBP2-89744]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-040-Immunocytochemistry-Immunofluorescence-NBP2-89744-img0001.jpg "Immunocytochemistry/ Immunofluorescence: TfR (Transferrin R) Antibody (040) [NBP2-89744]")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TFRC/9106R |
| Applications: | IHC |
![TfR (Transferrin R) Antibody (TFRC/9106R) Immunohistochemistry-Paraffin: TfR (Transferrin R) Antibody (TFRC/9106R) [NBP3-23693] -](https://resources.bio-techne.com/images/products/nbp3-23693_rabbit-tfr-transferrin-r-mab-tfrc-9106r-2412025874822.jpg "Immunohistochemistry-Paraffin: TfR (Transferrin R) Antibody (TFRC/9106R) [NBP3-23693] -")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #TFRC/1818 |
| Applications: | IHC, ELISA |
![Immunohistochemistry-Paraffin: TfR (Transferrin R) Antibody (TFRC/1818) [NBP2-53283]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-TFRC-1818-Immunohistochemistry-Paraffin-NBP2-53283-img0001.jpg "Immunohistochemistry-Paraffin: TfR (Transferrin R) Antibody (TFRC/1818) [NBP2-53283]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #TFRC/1149 |
| Applications: | WB |
![Western Blot: TfR (Transferrin R) Antibody (TFRC/1149) [NBP2-45008]](https://resources.bio-techne.com/images/products/TfR-Transferrin-R-Antibody-TFRC-1149-Western-Blot-NBP2-45008-img0001.jpg "Western Blot: TfR (Transferrin R) Antibody (TFRC/1149) [NBP2-45008]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #TFRC/1149 |
| Applications: | WB |
![TfR (Transferrin R) Antibody (TFRC/1149) - Azide and BSA Free Western Blot: TfR (Transferrin R) Antibody (TFRC/1149) - Azide and BSA Free [NBP3-11596] -](https://resources.bio-techne.com/images/products/nbp3-11596_mouse-monoclonal-tfr-transferrin-r-antibody-tfrc-1149-azide-and-bsa-free-24120258193567.jpg "Western Blot: TfR (Transferrin R) Antibody (TFRC/1149) - Azide and BSA Free [NBP3-11596] -")