SMURF2: Small Molecules and Peptides
SMURF-2 (SMAD ubiquitin regulatory factor-2) is an approximately 86 kDa, 748 amino acid cytoplasmic E3 ubiquitin ligase that negatively regulates TGF-beta signaling by promoting proteasomal degradation of some SMAD signaling molecules. It also influences cell cycle progression, peaking during mitosis and binding MAD2L1 and NEDD9/CASL.
1 result for "SMURF2 Small Molecules and Peptides" in Products
1 result for "SMURF2 Small Molecules and Peptides" in Products
SMURF2: Small Molecules and Peptides
SMURF-2 (SMAD ubiquitin regulatory factor-2) is an approximately 86 kDa, 748 amino acid cytoplasmic E3 ubiquitin ligase that negatively regulates TGF-beta signaling by promoting proteasomal degradation of some SMAD signaling molecules. It also influences cell cycle progression, peaking during mitosis and binding MAD2L1 and NEDD9/CASL.
HECT E3 ubiquitin ligase inhibitor
| Chemical Name: | N-(4-Acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide |
| Purity: | ≥98% (HPLC) |
