3 results for "SIK1/Snf1lk Small Molecules and Peptides" in Products
SIK1/Snf1lk: Small Molecules and Peptides
Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamberformation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation.Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing theCREB-specific coactivators, CRTC1-3
Potent and selective Lck and Src inhibitor; also inhibits SIK
| Alternate Names: | KIN112 |
| Chemical Name: | 2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate |
| Purity: | ≥98% (HPLC) |
Salt inducible kinase (SIK) inhibitor; also ULK1 and 2 inhibitor
| Chemical Name: | N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent pan-salt inducible kinases (SIK1, SIK2 and SIK3) inhibitor. Also inhibits Lat-B-induced EP differentiation via nuclear YAP1 accumulation.
| Alternate Names: | SIK inhibitor 1 |
| Chemical Name: | 1-(2,4-Dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)urea |
| Purity: | ≥98% (HPLC) |
