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6 results for "Retinoid X Receptor Agonists" in Products

Retinoid X Receptor Agonists Products

Retinoid X receptors (RXR) are members of the NR2B family of nuclear receptors and are common binding partners to many other nuclear receptors, including PPARs, liver X receptors (LXRs) and vitamin D receptors (VDR). RXR heterodimers act as ligand-dependent transcriptional regulators and increase the DNA-binding efficiency of its partner.

Despite numerous studies, the physiological role of RXRs have yet to been fully elucidated and, as they can also exist as homodimers, there is the possibility ...

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Endogenous retinoic acid receptor agonist

Alternate Names: Tretinoin,ATRA
Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
Purity: ≥98% (HPLC)
iPSC differentiation with retinoic acid
(2)

Pan RXR agonist

Alternate Names: BMS 649
Chemical Name: 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-benzoic acid
Purity: ≥98% (HPLC)
Pan RXR agonist

RXR agonist

Alternate Names: DHA
Chemical Name: (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoic acid
Purity: ≥98%
RXR agonist

Potent and selective RXR agonist

Alternate Names: LGD 1069
Chemical Name: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
Purity: ≥98% (HPLC)
Potent and selective RXR agonist

Potent and selective RXR agonist; also activates RXR/PPARγ heterodimers

Chemical Name: 6-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-pyridinecarboxylic acid
Purity: ≥98% (HPLC)
Potent and selective RXR agonist; also activates RXR/PPARγ heterodimers

Potent and selective RXRα agonist

Chemical Name: 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid
Purity: ≥97% (HPLC)
Potent and selective RXRα agonist
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