Ras Products
The Ras proteins (H-Ras, N-Ras, and two splice variants of K-Ras) define a closely related family of 21 kDa GTPases that cycle between GTP-bound active and GDP-bound inactive states at the cytoplasmic face of the plasma membrane. Receptor tyrosine kinases and G-protein coupled receptors activate Ras, and effectors include Raf and PI 3-kinase. Activating mutations of Ras, which impair GTPase activity and stabilize the active state, are found in nearly one-third of all human cancers.
55 results for "Ras" in Products
55 results for "Ras" in Products
Ras Products
The Ras proteins (H-Ras, N-Ras, and two splice variants of K-Ras) define a closely related family of 21 kDa GTPases that cycle between GTP-bound active and GDP-bound inactive states at the cytoplasmic face of the plasma membrane. Receptor tyrosine kinases and G-protein coupled receptors activate Ras, and effectors include Raf and PI 3-kinase. Activating mutations of Ras, which impair GTPase activity and stabilize the active state, are found in nearly one-third of all human cancers.
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #HL10 |
| Applications: | IHC, WB |
![Western Blot: Ras Antibody (HL10)G12D Mutant [NBP3-13647]](https://resources.bio-techne.com/images/products/Ras-Antibody-HL10-G12D-Mutant-Western-Blot-NBP3-13647-img0005.jpg "Western Blot: Ras Antibody (HL10)G12D Mutant [NBP3-13647]")
| Reactivity: | Human, Mouse, Rat, Zebrafish, Xenopus, +2 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Ras Antibody [NBP2-43784]](https://resources.bio-techne.com/images/products/Ras-Antibody-Western-Blot-NBP2-43784-img0007.jpg "Western Blot: Ras Antibody [NBP2-43784]")
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #342404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #342404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #342404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #342404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #342404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #342404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #342404 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #HL169 |
| Applications: | IHC, WB |
![Western Blot: Ras Antibody (HL169)G12V Mutant [NBP3-13668]](https://resources.bio-techne.com/images/products/Ras-Antibody-HL169-G12D-Mutant-Western-Blot-NBP3-13668-img0002.jpg "Western Blot: Ras Antibody (HL169)G12V Mutant [NBP3-13668]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #HL1153 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #342404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #342404 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6J9I4 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: Ras Antibody (6J9I4) [NBP3-15909]](https://resources.bio-techne.com/images/products/Ras-Antibody-3G8L8-Western-Blot-NBP3-15909-img0003.jpg "Western Blot: Ras Antibody (6J9I4) [NBP3-15909]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Ras AntibodyA59T Mutant [NBP3-13100]](https://resources.bio-techne.com/images/products/Ras-Antibody---A59T-Mutant-Western-Blot-NBP3-13100-img0001.jpg "Western Blot: Ras AntibodyA59T Mutant [NBP3-13100]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE44-13 |
| Applications: | WB, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Ras AntibodyG12V Mutant [NBP3-13132]](https://resources.bio-techne.com/images/products/Ras-Antibody---G12V-Mutant-Western-Blot-NBP3-13132-img0002.jpg "Western Blot: Ras AntibodyG12V Mutant [NBP3-13132]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Ras AntibodyQ61R Mutant [NBP3-13101]](https://resources.bio-techne.com/images/products/Ras-Antibody---Q61R-Mutant-Western-Blot-NBP3-13101-img0001.jpg "Western Blot: Ras AntibodyQ61R Mutant [NBP3-13101]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Ras AntibodyG13D Mutant [NBP3-13103]](https://resources.bio-techne.com/images/products/Ras-Antibody---G13D-Mutant-Western-Blot-NBP3-13103-img0001.jpg "Western Blot: Ras AntibodyG13D Mutant [NBP3-13103]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Ras AntibodyK117N Mutant [NBP3-13104]](https://resources.bio-techne.com/images/products/Ras-Antibody---K117N-Mutant-Western-Blot-NBP3-13104-img0001.jpg "Western Blot: Ras AntibodyK117N Mutant [NBP3-13104]")
| Reactivity: | Human |
| Details: | Rat IgG2B Monoclonal Clone #342404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2B Monoclonal Clone #342404 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2B Monoclonal Clone #342404 |
| Applications: | WB |
Ras signaling inhibitor; inhibits Ack1 and GCK
| Chemical Name: | N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide |
| Purity: | ≥98% (HPLC) |
