LC 2 Epimer
Tocris Bioscience, part of Bio-Techne | Catalog # 7421
Negative control for LC 2 (Cat. No. 7420)
Key Product Details
Description
Negative control for LC 2 (Cat. No. 7420)
Product Description
Negative control for LC 2 (Cat. No. 7420).Product Specifications
Molecular Weight
1132.80
Formula
C59H71ClFN11O7S
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(2S,4S)-1-((S)-2-(3-(3-((S)-2-(((7-(8-Chloronaphthalen-1-yl)-4-((S)-3-(cyanomethyl)-4-(2-fluoroacryloyl)piperazin-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)oxy)methyl)pyrrolidin-1-yl)propoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
CAS Number
2502156-12-7
InChI Key
ZCGQZLKPUVGCBQ-QDHBVFLESA-N
SMILES
CC1=C(SC=N1)C2=CC=C(CNC([C@@H]3C[C@H](O)CN3C([C@@H](NC(CCOCCCN4CCC[C@H]4COC5=NC(N6CCN([C@@H](CC#N)C6)C(C(F)=C)=O)=C7CCN(CC7=N5)C8=CC=CC9=C8C(Cl)=CC=C9)=O)C(C)(C)C)=O)=O)C=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 113.28 | 100 |
Preparing Stock Solutions
for LC 2 Epimer
The following data is based on the product molecular weight 1132.80
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.88 mL | 4.41 mL | 8.83 mL |
| 5 mM | 0.18 mL | 0.88 mL | 1.77 mL |
| 10 mM | 0.09 mL | 0.44 mL | 0.88 mL |
| 50 mM | 0.02 mL | 0.09 mL | 0.18 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bond Targeted degradation of oncogenic KRAS G12C by VHL-recruiting PROTACs. ACS Cent.Sci. 2020 PMID: 32875077
- De Vita The missing link between (un)druggable and degradable KRAS. ACS Cent.Sci. 2020 PMID: 32875070
Product Specific Notices for LC 2 Epimer
For research use only
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