RAR alpha/NR1B1: Small Molecules and Peptides
Retinoic Acid Receptor alpha (RAR alpha; NR1B1) is closely related to TR. RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RAR alpha is expressed in adult skin, and lung. RAR alpha is redundantly involved in vertebrates in the pleiotropic control of embryonic patterning and organogenesis, cell proliferation, differentiation and apoptosis, as well as homeostatic control.
12 results for "RAR alpha/NR1B1 Small Molecules and Peptides" in Products
12 results for "RAR alpha/NR1B1 Small Molecules and Peptides" in Products
RAR alpha/NR1B1: Small Molecules and Peptides
Retinoic Acid Receptor alpha (RAR alpha; NR1B1) is closely related to TR. RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RAR alpha is expressed in adult skin, and lung. RAR alpha is redundantly involved in vertebrates in the pleiotropic control of embryonic patterning and organogenesis, cell proliferation, differentiation and apoptosis, as well as homeostatic control.
Endogenous retinoic acid receptor agonist
| Alternate Names: | Tretinoin,ATRA |
| Chemical Name: | 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid |
| Purity: | ≥98% (HPLC) |
Retinoic acid analog; RAR agonist
| Alternate Names: | Ro 13-7410 |
| Chemical Name: | 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
Retinoic acid synthesized to Ancillary Material Grade
| Chemical Name: | 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E-nonatetraenoic acid |
| Purity: | ≥98% |
High affinity pan-RAR antagonist
| Chemical Name: | 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
RARα agonist; anticancer agent
| Alternate Names: | Tamibarotene |
| Chemical Name: | 4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
Retinoic acid analog; RARα agonist
| Chemical Name: | 4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoic acid |
| Purity: | ≥98% (HPLC) |
RARα-selective agonist
| Chemical Name: | 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]benzoic acid |
| Purity: | ≥98% (HPLC) |
Selective RARα antagonist
| Chemical Name: | 4-[5-[8-(1-Methylethyl)-4-phenyl-2-quinolinyl]-1H-pyrrolo-2-benzoic acid |
| Purity: | ≥98% (HPLC) |
Potent RAR agonist
| Chemical Name: | 4-[(1E)-3-[3,5-bis(1,1-Dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
Potent RXR antagonist
| Chemical Name: | 4-(7,8,9,10-Tetrahydro-5,7,7,10.10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]-diazepin-12-yl)-benzoic acid |
| Purity: | ≥98% (HPLC) |
Synthetic retinoid; induces differentiation of stem cells
| Chemical Name: | 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoic acid |
| Purity: | ≥99% (HPLC) |
Blocks retinoic acid metabolism
| Alternate Names: | R-75251 |
| Chemical Name: | 5-[(3-Chlorophenyl)-1H-imidazol-1-ylmethyl]-1H-benzimidazole dihydrochloride |
| Purity: | ≥98% (HPLC) |
