TTNPB
Tocris Bioscience, part of Bio-Techne | Catalog # 0761
Retinoic acid analog; RAR agonist
Key Product Details
Description
Retinoic acid analog; RAR agonist
Alternative Names
Ro 13-7410
Product Description
TTNPB is an extremely potent analog of retinoic acid, selective for the retinoic acid receptor (RAR) subtype. Enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs).Product Specifications
Molecular Weight
348.48
Formula
C24H28O2
Storage
Desiccate at -20°C
Purity
≥98% (HPLC)
Chemical Name
4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid
CAS Number
71441-28-6
PubChem ID
5289501
InChI Key
FOIVPCKZDPCJJY-JQIJEIRASA-N
SMILES
C\C(=C/C1=CC=C(C=C1)C(O)=O)C1=CC=C2C(=C1)C(C)(C)CCC2(C)C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 3.48 | 10 |
Preparing Stock Solutions
for TTNPB
The following data is based on the product molecular weight 348.48
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.70 mL | 143.48 mL | 286.96 mL |
| 0.5 mM | 5.74 mL | 28.70 mL | 57.39 mL |
| 1 mM | 2.87 mL | 14.35 mL | 28.70 mL |
| 5 mM | 0.57 mL | 2.87 mL | 5.74 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Loeliger Arotinoids, a new class of highly active retinoids. Eur.J.Med.Chem.-Chim.Ther.
- Hou Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science 2013 PMID: 23868920
- Minucci Retinoid X receptor-selective ligands produce malformations in Xenopus embryos. Proc.Natl.Acad.Sci.U.S.A. 1996 PMID: 8700839
Product Specific Notices for TTNPB
For research use only
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